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The map label for this gene is uvrC [H]

Identifier: 134302343

GI number: 134302343

Start: 1362170

End: 1364008

Strand: Reverse

Name: uvrC [H]

Synonym: FTW_1461

Alternate gene names: 134302343

Gene position: 1364008-1362170 (Counterclockwise)

Preceding gene: 134302346

Following gene: 134302342

Centisome position: 71.85

GC content: 34.04

Gene sequence:

>1839_bases
ATGATTGTAGATAATTCTAAAGATTTTGATTTAAAAAGTTTCTTGGCGAACTTGACTACACATTCCGGTGTTTATCGTAT
GCTTGATAAACATGGGGAGATAATTTATGTTGGTAAAGCAAAAAATCTTAAAAACCGTGTAAACAGTTATTTTTCAAAAG
GTGCTAAAGATAGTAAAACTTTAATGATGGTAGAGCAGATAGCCCGAATTGAGATAACTATTACCCCTAGTGACTATGAA
GCATATTTATTAGAAAATAATCTCATCAAGCAACATCGTCCTAAATACAATATTTTATTTAAAGATGATAAAAGTTACCC
ATATCTGGTAATTTCGCGTGATAAATTCCCTAGAGTATCTTTTTATCGTGGCAAATCAGCATATAAAAAAGGTCAATGTT
TTGGACCTTATGTGTCGATATCATCAGTTAAGAATACTCTAAATACTATTCAAAAAATTTTTCCAATCCGACAATGTGAA
AACTCATACTATAAATCTAGAGTTAGACCATGTTTACAATATCAAATTAAACGCTGTCTAGCACCATGTGTAGGTTTGGT
TTCTCAACAGCAATATGATGAGCAATTAGCAATTCTAAAAAAATTCTTAGCAGGCAAATTCAGTTCTGTTTTAGAAGAAA
TATCAGCGAAGATGTATCAGGCATCTGAAGATATGGAGTATGAGAAAGCTCAAGTTTATCGTGATCAATTGGTGGTGTTG
CGTAAATTACAACAGCAACAAATAGTTGATATTCAAGAGGATAAAACGTTTGATGTAATTGGTATATATATGCAAGATAG
CTATGCAAGTATAGCATTATTACAAATTCAAAATGGTGATGTTGTTGCCGATAGACATTGGAGTATAGATGCCAAAGGGC
AGGATAAAACCTCAATTATGCATGCTTTTTTATCACATTTTTATTTAGGAGATGAGATTCGTAATATTTGGCCTAAAAAT
ATAATCCTATCAAAAGTTGAGTTTGCTGATATTACCGATCTTATGAATAGTATTTCACAAAAAATTGGTCAAGCGATAAA
TTGGATAATTGCTCCAGCAGCTGATAATCTCAAGTGGCTCAAGTTAGCAGAAGTAAATGCACGACAAAAGCTAAATATCT
ACACAAGCTCAAAATCTCAGTATCAAAAACGCTTAGAATCACTCAAAGAATTTCTTGAGTTAGAAAAAGATATTAAGCGT
ATTGAATGTTTTGATATCTCACATTTTCAAGGTGAGGCAACCATAGCATCATGTGTCGTATACACAGATGATGGTGAAGA
TCGCAAATCTCATCGCAGATACAATATCAAAGATATCAAATCAGGAGATGACTATGCAGCAATTCATCAAGCAGTATCGC
GTCGAGTTAGTTCAGGGTTAGAGGCTGACAACCTCCCAGATGTAATGATAATAGATGGTGGTAAAGGGCAGATTCATCAA
GCAGAAGCAGTTTTTAGAGAGTATGGAATTCAAGATAAAGTCCAGATTGTAAGTTTGGGTAAAGGTGTTGAGCGTATAAG
TGGTAAAGAAAAAATCTACAAAGGTTTTGATGATACCGAATATACATTAGATGAACACAATCCAGGGTTTTTATTATTAC
GACAAGTTAGGGACTCTGCTCATGATCATGCAATTAAGGGTCAGCGTAAAAAAGTAAGTGCAAATAGACAGTCATCAATT
ATTGAAGAAATAGAAGGAGTTGGACCGAAGCGTCGCAAGGCTTTGATGATGTATTTTGGCGGTTGGCAAGAGTTATCTAG
AGCATCTGTTGATGAGATTGCAAAGGTCAAAGGAATTAGTAAAAAGTTAGCTCAAGAGATTTGGGAGTGCTTTCATTAA

Upstream 100 bases:

>100_bases
TAGTTAAAATACTTAGAGAAATTTAAACTTATGTATTTAGTTAGTATAAAAGTTTATATATGTTAACATTTTTCATAAAC
TCAGTGTTTAATAAAATTAG

Downstream 100 bases:

>100_bases
AAATACTAAACATCAGTAGCATAATGGCGTAGAATATTCGCATTTTAAAAATTATCAAATTAAAAAATGAATAAAAAAGG
TTCGCTACTGAGTACTTTAG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQIVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH

Sequences:

>Translated_612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQIVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH
>Mature_612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQIVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=614, Percent_Identity=43.8110749185668, Blast_Score=511, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 70306; Mature: 70306

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHH
LMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVS
HHHHHHHHEEEEEEECCCCEEEEHHCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCE
FYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCL
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIM
HHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCEEECCCEEECCCCCHHHHHH
HAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWL
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEE
KLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKRIECFDISHFQGEATIASCVV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEE
YTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
EECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
AEAVFREYGIQDKVQIVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSA
HHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHHCCCCCCCCEECCCCCCCEEHHHHHHHH
HDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGIS
HHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHCCHHHHHHHHHHH
KKLAQEIWECFH
HHHHHHHHHHCC
>Mature Secondary Structure
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHH
LMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVS
HHHHHHHHEEEEEEECCCCEEEEHHCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCE
FYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCL
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIM
HHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCEEECCCEEECCCCCHHHHHH
HAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWL
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEE
KLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKRIECFDISHFQGEATIASCVV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEE
YTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
EECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
AEAVFREYGIQDKVQIVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSA
HHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHHCCCCCCCCEECCCCCCCEEHHHHHHHH
HDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGIS
HHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHCCHHHHHHHHHHH
KKLAQEIWECFH
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA