Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 134302195

GI number: 134302195

Start: 1199682

End: 1200161

Strand: Direct

Name: lspA [H]

Synonym: FTW_1265

Alternate gene names: 134302195

Gene position: 1199682-1200161 (Clockwise)

Preceding gene: 134302194

Following gene: 134302197

Centisome position: 63.19

GC content: 29.58

Gene sequence:

>480_bases
TTGCTTAGACCAAAATTGAAATATTTTATTTTAGCAATTTTAATTATTGCCGCTGACTTATACACTAAGTATTTAGCAAA
TACATACCTAGAATTTGCTCAATCTCTTAAGATAACTAGTTTCTTTAATCTTACGTTGTTATACAATCATGGCGCAGCAT
TTAGTCTTCTAAGCAATGATCAAACATCATGGCAAATGATAATGTTTTCTACAATCTCTCTAATTGCTGCTATTGTACTT
ATTTATCTAATTATTAAACAACCAATTACTGAGAAAATTAATTTGTTCTCTTTTGCTCTTATTCTAGGTGGTGCTTTAGG
CAACTTTTACGATCGTGCTTTTCAAGGATATGTAATCGATTTTTTAGATTTTCACATAGGTAATTATCACTGGCCGTCAT
TTAATATAGCTGATTCAGCTATCACATGTGGTGTTGTAATTTTGATAGCAGCTTCACTATTTACTAAAAAAAAATCATAA

Upstream 100 bases:

>100_bases
TGGCACCGTAGCTCGACTGTTGGGGATAATCCTCAATACAAAGATATTTGTAGTCGCTGTGTTGAGAATATAACTACAGA
AGCTGGAGAGTCGCGTGAAT

Downstream 100 bases:

>100_bases
TGTTTTTTTGTAATCAGTATAAAATTGACGTGCTTTAAATTCATTACCACCATAAGATATATTATAGATTGTCTGATCCA
TCCTCGAATCCTGTTGCAGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSNDQTSWQMIMFSTISLIAAIVL
IYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVIDFLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS

Sequences:

>Translated_159_residues
MLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSNDQTSWQMIMFSTISLIAAIVL
IYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVIDFLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS
>Mature_159_residues
MLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSNDQTSWQMIMFSTISLIAAIVL
IYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVIDFLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=152, Percent_Identity=32.8947368421053, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17954; Mature: 17954

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCC
QTSWQMIMFSTISLIAAIVLIYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS
HHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCC
QTSWQMIMFSTISLIAAIVLIYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS
HHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA