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The map label for this gene is pilQ [H]

Identifier: 134302144

GI number: 134302144

Start: 1129748

End: 1131520

Strand: Reverse

Name: pilQ [H]

Synonym: FTW_1195

Alternate gene names: 134302144

Gene position: 1131520-1129748 (Counterclockwise)

Preceding gene: 134302145

Following gene: 134302143

Centisome position: 59.6

GC content: 35.53

Gene sequence:

>1773_bases
ATGTTTTTTGCAAAAAAGAAGTTATTAGTTGTTCTAACAATATTGGGTGGTATTCTAGGTTATGATGTCTCGGTAGCTGA
TACTAAAGAATCTCAAGTATCTAATCAGCCGCAAACTTCAGAGCAGCCTGTAGCCAAAATTGTTGGTCGAGAGGAAAATA
AAGATAAAGTTACTGATAAACATATCAAAGATCTTGAATTTCATCGTAGTTTAAATGGTAGTGCTGTTTTTGAAGTTGCT
TTTGAGGAGAATATAAGTAATTTTTCGGGCTATAAAACTAAGCTGTCACAAGATGGCTATACACTGACAATAACTTTTAA
TGATACCACTATATCGGATAAGTGGGTTAGTAATATTGATACTAAAGTTTTTAACACTATAGTTGATTCGATCAAGATTT
TTAAAGAAGGTGAAAGTGTCGTTTTTGTAATTCATTCTCTTGATAGAATTTCTCTAAGTGACTTCAAAGAAGGTAATATA
TTTAAGTTTAAAATTGATAGACGCAACAGCCGTGTTGAAGGATTTAATGTTAATGAGCCAATTTCAATATCTTTCAAAGA
TGCTCCAGTGCAGACTGTATTACAGGTGTTATCTGAATTTGCTGGTCTAAATCTAGTGGTTAGTAGTAGTGTGCGTGGTA
ATATTTCTATTGATCTAAAAAATGTGCCTTGGAATGAGGTGATGAATATTGTATTAGTCAGTAAAGGTCTAGCTACAAAA
AAAATGAGTAGTATATTATATGTAGCTACTGCCGCTGAAATTGCAGCTCAAGAGCAGTTAGAGTTACAAACAAAACGTTC
ATTGGAAAATAATGCTACCTTGGTGACAGAATTTATACCATTAAACTATACTACTGCTCAGGCTGCACAAACGGTTATTA
CTTCAATGGCAAAACAAAATGGTGGTATTATGTCACCCCGAGGTAGTATTACTGCGGATGCACGTACAAATACTTTAATA
GTAACAGATACCAAAGAAAAATTGCAGCGTATCAAAGAGGTTGTTAATGAGATTGATATTCCAAATGATCAAGTTTTGAT
AGAAGCTAGAATAGTCGAAGTACTTAGAACAAGTGCACTTGAACTTGGCTTTAACTATGGTGTTGTTGATCCTTCTGGTA
GAGTTAACATAGGTCTAGATACTTTTAATAGTAATCCTAATCCTGCTCCAGGACCAACTCCAACCCCAGTAGATACTTTT
GTTGGGACAACAGCAAAGCTAGCGTATACTATAGCTGGAGGAGTAAGGCTTGAGATGGAAGTCAGAGCTCTTGAGAGTGA
GTCACTAGCAGAAGAAGTGGCATCTCCACACCTAGTAGTTGCAAATAACCAAGTAGCATTTATCAAAGATGGTGAAGATG
TACCATATAACCAAGCAACAGCTTCTGGTGCCGCAGCTGTTGCTTTCCAAGAGGCGGTTTTAGAATTACAAGTTACGCCA
CAAATTGCTCCTGATGGTAATATTATTATGGATATTCTTGTTACTAAAAACTCAGTAGGAGCTTCTCCTGGTAAAACCCC
ACAAGGAGGTGATTTGCCACCAATTATCAAAAAGAGAGAGATAACCACCAAAGTTATGACCAAAGATGGTGATACTGTCG
TAATTGGTGGGATATACCAAAAAACCCAAAAAGAAGAGCGTAATAAAATCCCATTCTTAGGTGATATTCCTTATTTGGGT
TATCTATTTAGTTATACGAAAATTACTGATCAGGATTCTGAGTTGTTAATTTTTATAACTCCAAAAATCATTGAGTCAAG
AGTCCAAAAATGA

Upstream 100 bases:

>100_bases
TGTAACCAAAGAAGGTATTGTTATTGATGAGTGGAAGAAGGATGACCTCAAGAGAGTCTGGGAAAAGATTCAAACTGTTA
TACATTAGTAAGGTAAAGTG

Downstream 100 bases:

>100_bases
TAGCAGATAATAGTTGCAAAAATATCAATATTTAGGTATCTTATAGCCTATAATTTTTTATGTACAAGGGGTGATTAGTA
ACTAACTATCACGGTGTGTA

Product: type IV pilus secretin/type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKDLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGESVVFVIHSLDRISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRSLENNATLVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTKEKLQRIKEVVNEIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSGRVNIGLDTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK

Sequences:

>Translated_590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKDLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGESVVFVIHSLDRISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRSLENNATLVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTKEKLQRIKEVVNEIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSGRVNIGLDTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK
>Mature_590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKDLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGESVVFVIHSLDRISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRSLENNATLVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTKEKLQRIKEVVNEIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSGRVNIGLDTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=429, Percent_Identity=34.032634032634, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082242, Length=392, Percent_Identity=28.8265306122449, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 64553; Mature: 64553

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDK
CCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHH
HIKDLEFHRSLNGSAVFEVAFEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNID
HHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TKVFNTIVDSIKIFKEGESVVFVIHSLDRISLSDFKEGNIFKFKIDRRNSRVEGFNVNEP
HHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
EEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHEEEEEECCCCHH
KMSSILYVATAAEIAAQEQLELQTKRSLENNATLVTEFIPLNYTTAQAAQTVITSMAKQN
HHHHEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GGIMSPRGSITADARTNTLIVTDTKEKLQRIKEVVNEIDIPNDQVLIEARIVEVLRTSAL
CCEECCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
ELGFNYGVVDPSGRVNIGLDTFNSNPNPAPGPTPTPVDTFVGTTAKLAYTIAGGVRLEME
HCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCHHEEEEEEECCEEEEEE
VRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
EEHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEECC
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQ
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHH
KTQKEERNKIPFLGDIPYLGYLFSYTKITDQDSELLIFITPKIIESRVQK
HHHHHHHCCCCEEECCCHHHHHHHHHEECCCCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDK
CCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHH
HIKDLEFHRSLNGSAVFEVAFEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNID
HHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TKVFNTIVDSIKIFKEGESVVFVIHSLDRISLSDFKEGNIFKFKIDRRNSRVEGFNVNEP
HHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
EEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHEEEEEECCCCHH
KMSSILYVATAAEIAAQEQLELQTKRSLENNATLVTEFIPLNYTTAQAAQTVITSMAKQN
HHHHEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GGIMSPRGSITADARTNTLIVTDTKEKLQRIKEVVNEIDIPNDQVLIEARIVEVLRTSAL
CCEECCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
ELGFNYGVVDPSGRVNIGLDTFNSNPNPAPGPTPTPVDTFVGTTAKLAYTIAGGVRLEME
HCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCHHEEEEEEECCEEEEEE
VRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
EEHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEECC
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQ
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHH
KTQKEERNKIPFLGDIPYLGYLFSYTKITDQDSELLIFITPKIIESRVQK
HHHHHHHCCCCEEECCCHHHHHHHHHEECCCCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]