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The map label for this gene is ybeC [H]

Identifier: 134302137

GI number: 134302137

Start: 1121034

End: 1122542

Strand: Reverse

Name: ybeC [H]

Synonym: FTW_1188

Alternate gene names: 134302137

Gene position: 1122542-1121034 (Counterclockwise)

Preceding gene: 134302138

Following gene: 134302136

Centisome position: 59.13

GC content: 34.13

Gene sequence:

>1509_bases
ATGAGTAATAATGTATCTGTAAAAAAGATGTCGTTGTTTAGTGCCATATTGATTGGCACTACTTGTATGGTTGGCTCTGG
CTGGCTATTTAGTGCTCAGCTTACAGCTAAAAATGCCGGCAACTGGGCTTTTTTAGCATGGATTTTAGCTGCGCTAATTG
TTGTGATGATTGCTCTATGTTTAGGGAAAGTAGTATCTTTGTATCCTGTTAGAGGAGCTACAACTAGATCTAGTGCAATA
TCACATAATAGTATTTTTGCAATGCCATTTGCTTTTGCAAACTGGTTTGGTATTGTCGTAGTTATTTCATCTGAAGCATT
AGCAACTACTCAGTATCTATCAGGCGTTAAGTCTATGCAATGGCTTATGAGTGATGGTGTTCTGACTACAGCTGGAACAG
CTTTTGCACTATTTGTGTTATTTGTATATCTAGTGATTAATTTTTATGGTGTGAAGGTTTTGGCTAAGGTAAATAACGCT
ATAACTGTTTTTAAGATGGCGGTACCGTTTATTATTGTTATAATATTTATAACTTATGATTTTATGCATAGTTCTGACCA
TGTAAGCATGTTTTCAGAAGATATTCCTAATAACTCTCAATTTGGATTTAGTTCAGCATTGACAGCAATTGTTGCGGGTG
GTTTGATCTACACTTTCAATGGTTTTCAGACTGTTGTTGCTTATGCAAGTGAAGTTAAGAATCCTGGTAGAAATATTCCT
TTAGCAATTATTTTAGCGTTATTGATAGTTTTAGTTTTATATCTAGGCTTACAGTACGCGTTTATGCAGGCAGTTCCTCA
TCAATACCTATTAGATAAAGGTGGTTGGGCAGGTCTTGATTTTGACTCTCCATTATTACAAATAGCAACTCTTTTAGGAC
TTGGTTATATATCTTTTTTACTTATAGTTGATAGTGTCATTAGTCCATCAGCTACAGGTTATACATATCTAGGAGCTTCT
TCGAGAATGCTCTATGCGATGTCTTCAGAGGGGCAGATGCCAAGATATTTTGCTAAGATTACTCCAATAGTAAATATCTC
GCGTAGATCTTTATTAGCGAATTTTATTTTATCGGTTATATTTTTGTTTTTCTCAGATAACTGGACAGGTCTAATGCTTG
TTGTGACAGGTTTTCATATTATTGGATATATGGCTGCTCCTGTGAGTATGGGAGCTTTAGCACCACGTACAAGGCTATTT
GGTTTAGTTGTATTTGTAGTTCTGACATTATTACTTAATACTGTAGAAATTCAGACTCAGATAAACATGAGTGTGATTCT
TATTGTTTTAATGACTATATATGCAAGTCTTGAGTTTAGAAGAATAGGTATTAAGAATCTTTTAATGCTTATATTACCGT
TTATAATTTTTGTTTGTTTAACTACGCCTATAACAAATTATTTTGCTGATGCAATCGTAGGTGTGATATTTTACTGGTTT
GTTACAGATAAGCGTTATGTCGCATTCTGTAGATCTACAGCAAATGAGAAAAATATTATTGTCGATTAA

Upstream 100 bases:

>100_bases
CTAACTTTATAGGTTAGTCATTATCAAATAATCACAGTGAAAGCAAAGTTATAATTACCTCTGCTTTCATCTAACTTAAA
AATTAATATAAGGAAAGAAT

Downstream 100 bases:

>100_bases
TCGCTTATTAACTATAGTCTTTGAGATTTTATATATCTATAATACAACTCTAATATTACCAAGTTCTACCAAATAATGAA
AAGTACAAAATGGATTTTAG

Product: amino acid transporter

Products: Proton [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSNNVSVKKMSLFSAILIGTTCMVGSGWLFSAQLTAKNAGNWAFLAWILAALIVVMIALCLGKVVSLYPVRGATTRSSAI
SHNSIFAMPFAFANWFGIVVVISSEALATTQYLSGVKSMQWLMSDGVLTTAGTAFALFVLFVYLVINFYGVKVLAKVNNA
ITVFKMAVPFIIVIIFITYDFMHSSDHVSMFSEDIPNNSQFGFSSALTAIVAGGLIYTFNGFQTVVAYASEVKNPGRNIP
LAIILALLIVLVLYLGLQYAFMQAVPHQYLLDKGGWAGLDFDSPLLQIATLLGLGYISFLLIVDSVISPSATGYTYLGAS
SRMLYAMSSEGQMPRYFAKITPIVNISRRSLLANFILSVIFLFFSDNWTGLMLVVTGFHIIGYMAAPVSMGALAPRTRLF
GLVVFVVLTLLLNTVEIQTQINMSVILIVLMTIYASLEFRRIGIKNLLMLILPFIIFVCLTTPITNYFADAIVGVIFYWF
VTDKRYVAFCRSTANEKNIIVD

Sequences:

>Translated_502_residues
MSNNVSVKKMSLFSAILIGTTCMVGSGWLFSAQLTAKNAGNWAFLAWILAALIVVMIALCLGKVVSLYPVRGATTRSSAI
SHNSIFAMPFAFANWFGIVVVISSEALATTQYLSGVKSMQWLMSDGVLTTAGTAFALFVLFVYLVINFYGVKVLAKVNNA
ITVFKMAVPFIIVIIFITYDFMHSSDHVSMFSEDIPNNSQFGFSSALTAIVAGGLIYTFNGFQTVVAYASEVKNPGRNIP
LAIILALLIVLVLYLGLQYAFMQAVPHQYLLDKGGWAGLDFDSPLLQIATLLGLGYISFLLIVDSVISPSATGYTYLGAS
SRMLYAMSSEGQMPRYFAKITPIVNISRRSLLANFILSVIFLFFSDNWTGLMLVVTGFHIIGYMAAPVSMGALAPRTRLF
GLVVFVVLTLLLNTVEIQTQINMSVILIVLMTIYASLEFRRIGIKNLLMLILPFIIFVCLTTPITNYFADAIVGVIFYWF
VTDKRYVAFCRSTANEKNIIVD
>Mature_501_residues
SNNVSVKKMSLFSAILIGTTCMVGSGWLFSAQLTAKNAGNWAFLAWILAALIVVMIALCLGKVVSLYPVRGATTRSSAIS
HNSIFAMPFAFANWFGIVVVISSEALATTQYLSGVKSMQWLMSDGVLTTAGTAFALFVLFVYLVINFYGVKVLAKVNNAI
TVFKMAVPFIIVIIFITYDFMHSSDHVSMFSEDIPNNSQFGFSSALTAIVAGGLIYTFNGFQTVVAYASEVKNPGRNIPL
AIILALLIVLVLYLGLQYAFMQAVPHQYLLDKGGWAGLDFDSPLLQIATLLGLGYISFLLIVDSVISPSATGYTYLGASS
RMLYAMSSEGQMPRYFAKITPIVNISRRSLLANFILSVIFLFFSDNWTGLMLVVTGFHIIGYMAAPVSMGALAPRTRLFG
LVVFVVLTLLLNTVEIQTQINMSVILIVLMTIYASLEFRRIGIKNLLMLILPFIIFVCLTTPITNYFADAIVGVIFYWFV
TDKRYVAFCRSTANEKNIIVD

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=369, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=428, Percent_Identity=21.0280373831776, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=428, Percent_Identity=21.0280373831776, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24667468, Length=375, Percent_Identity=23.7333333333333, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 55090; Mature: 54959

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNVSVKKMSLFSAILIGTTCMVGSGWLFSAQLTAKNAGNWAFLAWILAALIVVMIALC
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGKVVSLYPVRGATTRSSAISHNSIFAMPFAFANWFGIVVVISSEALATTQYLSGVKSMQ
HHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHH
WLMSDGVLTTAGTAFALFVLFVYLVINFYGVKVLAKVNNAITVFKMAVPFIIVIIFITYD
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FMHSSDHVSMFSEDIPNNSQFGFSSALTAIVAGGLIYTFNGFQTVVAYASEVKNPGRNIP
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHEEECHHHHHHHHHHHHCCCCCCCC
LAIILALLIVLVLYLGLQYAFMQAVPHQYLLDKGGWAGLDFDSPLLQIATLLGLGYISFL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LIVDSVISPSATGYTYLGASSRMLYAMSSEGQMPRYFAKITPIVNISRRSLLANFILSVI
HHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFFSDNWTGLMLVVTGFHIIGYMAAPVSMGALAPRTRLFGLVVFVVLTLLLNTVEIQTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INMSVILIVLMTIYASLEFRRIGIKNLLMLILPFIIFVCLTTPITNYFADAIVGVIFYWF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTDKRYVAFCRSTANEKNIIVD
HCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNNVSVKKMSLFSAILIGTTCMVGSGWLFSAQLTAKNAGNWAFLAWILAALIVVMIALC
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGKVVSLYPVRGATTRSSAISHNSIFAMPFAFANWFGIVVVISSEALATTQYLSGVKSMQ
HHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHH
WLMSDGVLTTAGTAFALFVLFVYLVINFYGVKVLAKVNNAITVFKMAVPFIIVIIFITYD
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FMHSSDHVSMFSEDIPNNSQFGFSSALTAIVAGGLIYTFNGFQTVVAYASEVKNPGRNIP
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHEEECHHHHHHHHHHHHCCCCCCCC
LAIILALLIVLVLYLGLQYAFMQAVPHQYLLDKGGWAGLDFDSPLLQIATLLGLGYISFL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LIVDSVISPSATGYTYLGASSRMLYAMSSEGQMPRYFAKITPIVNISRRSLLANFILSVI
HHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFFSDNWTGLMLVVTGFHIIGYMAAPVSMGALAPRTRLFGLVVFVVLTLLLNTVEIQTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INMSVILIVLMTIYASLEFRRIGIKNLLMLILPFIIFVCLTTPITNYFADAIVGVIFYWF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTDKRYVAFCRSTANEKNIIVD
HCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-lysine [Periplasm] = Proton [Cytoplasm] + L-lysine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]