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The map label for this gene is hflC [H]

Identifier: 134302059

GI number: 134302059

Start: 1035179

End: 1036105

Strand: Reverse

Name: hflC [H]

Synonym: FTW_1095

Alternate gene names: 134302059

Gene position: 1036105-1035179 (Counterclockwise)

Preceding gene: 134302060

Following gene: 134302058

Centisome position: 54.58

GC content: 33.66

Gene sequence:

>927_bases
ATGAGTAAATTCCTAAAAATATTCTTAGTGCTTGTAGTAGTCTTAGCTATAGTAGTATTAAGCACAAAATTTATTGTCAA
ACAAGGCTCAGAAGCAGTTATTCTAAGACTTGGTGAACTTGTAAAGGATAAAGATGGCAAAGCTGTAGAGTATGAACCAG
GTTTACATATTAAAATCCCATTTATAGATACAGTTAAAATGTACGATATGCGTAACCGAGTTTTAGAGGCTGATTCTGCT
CGTGTAGTTACTAAAGAGCAAAAAGATGTACTGATTAATGCCTATGTGGTTTGGAAGATAAGTAATAACAATATTTCTAC
ATTTTACACAAGTACTAGTGGTAGTGTTGATCGAGCTGAGACATTATTAAAACAATTCTTGGAGTCTTCTTTAAGAGCAG
AGGTTGGTAATAATGATATTCAAAGTTTGATTAATAATAATCGTGATAAACTAATGATCGCTTTAACTAAGAGTGTCCAA
CAACAAGCTAAGCAAATCGGTGTAGATGTTATCGATGTGCGAGTAAAACAGATAGATTTACCTGAAACAGTTACAGATTC
TATCTACCAAAGAATGAGATCTTCTCGCCAAAAAGTAGCGGCTTCTATCCGTGCTGAAGGTAAGCAATTAGCTGAGAAAA
TAAAAGCTGCAGCAGATGCTAAAGTAACAGTTACATTAGCAGAAGCAGAAAAAGAATCAAAAACTATAATGGCAGAAGCA
GATGCCAAAGCAGCTAAGATTTTTACCCAAGCTTATTCTAAATCAGTACCGTTATATGAGTTTCTAAAGAGTATGAACTC
CTATAAAGAGAGTTTTAACGGTAAGAATGAAGTCGTATTTATGCTTAAACCAGATAGTAAGTTTTTCCAAGGTTTTAAAT
TGGAACCAAATAGCAAACTTGCTGAAGATATGAAGGAAGCTAAATAA

Upstream 100 bases:

>100_bases
ATATTCTTGATAGATGGTGATGGTGCTAAGAATATTTTCTACGGTTTAAGTGATACACAAAAACAAGCACTATTATCAAA
TACGCAAGGAGGAAATTAAG

Downstream 100 bases:

>100_bases
ATGAGTAAAGTAAAAGTACTTTTTGTATGTAAAGGTAATATTTGTCGGTCGCCTACTGCACATGGTATTTTCCGTGATAT
TGTTAAGCGGTATAACTTAG

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSKFLKIFLVLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSA
RVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQ
QQAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
DAKAAKIFTQAYSKSVPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLEPNSKLAEDMKEAK

Sequences:

>Translated_308_residues
MSKFLKIFLVLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSA
RVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQ
QQAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
DAKAAKIFTQAYSKSVPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLEPNSKLAEDMKEAK
>Mature_307_residues
SKFLKIFLVLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSAR
VVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQ
QAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEAD
AKAAKIFTQAYSKSVPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLEPNSKLAEDMKEAK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=315, Percent_Identity=36.8253968253968, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786697, Length=256, Percent_Identity=23.4375, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 34545; Mature: 34414

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFLKIFLVLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FIDTVKMYDMRNRVLEADSARVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAE
CCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHH
TLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQQAKQIGVDVIDVRVKQIDL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCEEEEEEEEECCC
PETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECC
DAKAAKIFTQAYSKSVPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLEPNSKL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCCHH
AEDMKEAK
HHHHHHCC
>Mature Secondary Structure 
SKFLKIFLVLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FIDTVKMYDMRNRVLEADSARVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAE
CCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHH
TLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQQAKQIGVDVIDVRVKQIDL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCEEEEEEEEECCC
PETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECC
DAKAAKIFTQAYSKSVPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLEPNSKL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCCHH
AEDMKEAK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]