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The map label for this gene is yfkJ [H]

Identifier: 134302058

GI number: 134302058

Start: 1034693

End: 1035178

Strand: Reverse

Name: yfkJ [H]

Synonym: FTW_1094

Alternate gene names: 134302058

Gene position: 1035178-1034693 (Counterclockwise)

Preceding gene: 134302059

Following gene: 134302057

Centisome position: 54.53

GC content: 35.8

Gene sequence:

>486_bases
ATGAGTAAAGTAAAAGTACTTTTTGTATGTAAAGGTAATATTTGTCGGTCGCCTACTGCACATGGTATTTTCCGTGATAT
TGTTAAGCGGTATAACTTAGAAAGTCATATTGATGTGGCATCCTGTGGTACAAGCTCACGGATGTGGGGACATGAAGGGC
ACGGAGCTGATATGCGTACATTAGAAATGGCAAAGAAATATGATTGTGATCTTTCAGATCAAGTTTCACAGCAGTTAGAG
GAGGCGGCTTTTGACGAATATGATTATATCGTCGCAATGGATCAAGAGAATATTGATACAATGAAAGAGATGTTTCCAAA
TGCTGATTTTTCAAAAGTCTCAAGAATGTTGGAATATGCTCCTGCTATTGCTTTGGATGATGTGCCAGATCCATATTTTG
AAAATAATTTTGAAAAAGTTTTTTTGATGATAGATACAGCATGTCAAGGACTCTTTGAAAAGATAAGGTTAGAGTATAAA
TTATGA

Upstream 100 bases:

>100_bases
TGAAGTCGTATTTATGCTTAAACCAGATAGTAAGTTTTTCCAAGGTTTTAAATTGGAACCAAATAGCAAACTTGCTGAAG
ATATGAAGGAAGCTAAATAA

Downstream 100 bases:

>100_bases
ATTATAGTAAAGCAAAATATATAATGGGTGCGGCAAAGGTTTCACAGCTTCCAGAAGATACTGGTGTGGAAGTTGCTTTT
GCAGGACGTTCAAATGCTGG

Product: low molecular weight (LMW) phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSKVKVLFVCKGNICRSPTAHGIFRDIVKRYNLESHIDVASCGTSSRMWGHEGHGADMRTLEMAKKYDCDLSDQVSQQLE
EAAFDEYDYIVAMDQENIDTMKEMFPNADFSKVSRMLEYAPAIALDDVPDPYFENNFEKVFLMIDTACQGLFEKIRLEYK
L

Sequences:

>Translated_161_residues
MSKVKVLFVCKGNICRSPTAHGIFRDIVKRYNLESHIDVASCGTSSRMWGHEGHGADMRTLEMAKKYDCDLSDQVSQQLE
EAAFDEYDYIVAMDQENIDTMKEMFPNADFSKVSRMLEYAPAIALDDVPDPYFENNFEKVFLMIDTACQGLFEKIRLEYK
L
>Mature_160_residues
SKVKVLFVCKGNICRSPTAHGIFRDIVKRYNLESHIDVASCGTSSRMWGHEGHGADMRTLEMAKKYDCDLSDQVSQQLEE
AAFDEYDYIVAMDQENIDTMKEMFPNADFSKVSRMLEYAPAIALDDVPDPYFENNFEKVFLMIDTACQGLFEKIRLEYKL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=154, Percent_Identity=33.1168831168831, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI6005988, Length=153, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325330, Length=147, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=5e-18,
Organism=Drosophila melanogaster, GI78706770, Length=159, Percent_Identity=31.4465408805031, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706772, Length=159, Percent_Identity=31.4465408805031, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706766, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI78706768, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI78706764, Length=134, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18518; Mature: 18387

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVKVLFVCKGNICRSPTAHGIFRDIVKRYNLESHIDVASCGTSSRMWGHEGHGADMRT
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCHHH
LEMAKKYDCDLSDQVSQQLEEAAFDEYDYIVAMDQENIDTMKEMFPNADFSKVSRMLEYA
HHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHC
PAIALDDVPDPYFENNFEKVFLMIDTACQGLFEKIRLEYKL
CCCCCCCCCCCHHCCCHHEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKVKVLFVCKGNICRSPTAHGIFRDIVKRYNLESHIDVASCGTSSRMWGHEGHGADMRT
CCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCHHH
LEMAKKYDCDLSDQVSQQLEEAAFDEYDYIVAMDQENIDTMKEMFPNADFSKVSRMLEYA
HHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHC
PAIALDDVPDPYFENNFEKVFLMIDTACQGLFEKIRLEYKL
CCCCCCCCCCCHHCCCHHEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]