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The map label for this gene is thrC [H]

Identifier: 134302056

GI number: 134302056

Start: 1032785

End: 1033786

Strand: Reverse

Name: thrC [H]

Synonym: FTW_1092

Alternate gene names: 134302056

Gene position: 1033786-1032785 (Counterclockwise)

Preceding gene: 134302057

Following gene: 134302055

Centisome position: 54.45

GC content: 36.53

Gene sequence:

>1002_bases
ATGCCGATAAAAGATCCATCAAGCTTTGTATCTTTAAGAGAATCAGCTACACCATTGCTTAAGAGTAAAATAATAGGCAA
AGAGTTAGGAATTAATCTATACTTTAAAGTCGAAGGTAAAAACCCTACTGGTTCATTTAAAGATAGAGGATCAGCAGTTG
ATATAACAGTTGCAAAAGAGCTTGGTGCTAAAGGGATAGTACTAGCATCTACTGGTAACATGGCGGCTTCATGTGCTTGT
TACGCTGCAGCTGCGAAGATGCCTTGCTTTATTATTGTGCCAGAAGGTGTAGCAGCTTCTAAGTTGGCTCAGGTAATGTC
TTATGGGGGAAAAATAGTTCAGGTTAAGGGTAGTTATAATGAAGATGCAAAGTTAGCTTATGATATTGCAAAATCAAAAG
ATTTCTTCTTGGCTGGAGACTATGCTTTTAGAGTTGAAGGTCAAAAAACCGCAGCATTTGAACTAATAGATCAGTTATTG
TTCCAAGTGCCAGATGAGGTTATAATACCTATAGGTTGTGGCACAAATATGACAGCTTATTATAAAGGTTTTTGTGAGTA
TAAAGAGTTAGGTTTTATTAATTCTTTACCTAAGCTTACTGGTGTTCAATCTACTGAAGCTGATACCTTAGCTAGAGCAT
ATCAGAAAAATCAAAATAGAATTGAGCCTCTAAAAACAGCAAATACAATAGCAACAGCAATAGCTGTGCCGTATCCTATC
GATGGTGATAAAGCTATATATAGTACAGGTGGAGAATCTACAGCTGTAACAGACATGAAAATGCTAGAGGCTCAATATTT
GCTATCTACTAAAGAGGGATTATTTGTTGAGTTAGCATCCGCGTCAACTATTGCACACTTACTCAAAAAGTATGAGGAAG
GAAAGCTTCAAAAAGGTAGTACAGTAGTATGTGTATTATCTGGAGAAGGTCTAAAAGATCCAGGTGTTGTGCTTATCAGC
TATTCAACCACCAATTATATATCCTTCAGAAACAGATTTTGA

Upstream 100 bases:

>100_bases
GCCCTGGGAAATTCAGATGAATATTAATGAAATAAGTAAAAAAATTAACAAAGATTATTTTACTTAAGCCTCGCCATGTT
TATCTAAGTATATTCCCTTT

Downstream 100 bases:

>100_bases
CAGACTGTATAATAGTCATTTTTTTGACAACAAGACGATGTTATTTATAGAGCAAAATGAAGTTATATTTGATAAATTAC
TTACTCTTGATGAAGTCAAA

Product: putative threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPIKDPSSFVSLRESATPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKELGAKGIVLASTGNMAASCAC
YAAAAKMPCFIIVPEGVAASKLAQVMSYGGKIVQVKGSYNEDAKLAYDIAKSKDFFLAGDYAFRVEGQKTAAFELIDQLL
FQVPDEVIIPIGCGTNMTAYYKGFCEYKELGFINSLPKLTGVQSTEADTLARAYQKNQNRIEPLKTANTIATAIAVPYPI
DGDKAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIAHLLKKYEEGKLQKGSTVVCVLSGEGLKDPGVVLIS
YSTTNYISFRNRF

Sequences:

>Translated_333_residues
MPIKDPSSFVSLRESATPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKELGAKGIVLASTGNMAASCAC
YAAAAKMPCFIIVPEGVAASKLAQVMSYGGKIVQVKGSYNEDAKLAYDIAKSKDFFLAGDYAFRVEGQKTAAFELIDQLL
FQVPDEVIIPIGCGTNMTAYYKGFCEYKELGFINSLPKLTGVQSTEADTLARAYQKNQNRIEPLKTANTIATAIAVPYPI
DGDKAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIAHLLKKYEEGKLQKGSTVVCVLSGEGLKDPGVVLIS
YSTTNYISFRNRF
>Mature_332_residues
PIKDPSSFVSLRESATPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKELGAKGIVLASTGNMAASCACY
AAAAKMPCFIIVPEGVAASKLAQVMSYGGKIVQVKGSYNEDAKLAYDIAKSKDFFLAGDYAFRVEGQKTAAFELIDQLLF
QVPDEVIIPIGCGTNMTAYYKGFCEYKELGFINSLPKLTGVQSTEADTLARAYQKNQNRIEPLKTANTIATAIAVPYPID
GDKAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIAHLLKKYEEGKLQKGSTVVCVLSGEGLKDPGVVLISY
STTNYISFRNRF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=175, Percent_Identity=29.7142857142857, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790207, Length=157, Percent_Identity=28.6624203821656, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17508781, Length=147, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322631, Length=161, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 35817; Mature: 35685

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKDPSSFVSLRESATPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKE
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCEEEEEEHHH
LGAKGIVLASTGNMAASCACYAAAAKMPCFIIVPEGVAASKLAQVMSYGGKIVQVKGSYN
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
EDAKLAYDIAKSKDFFLAGDYAFRVEGQKTAAFELIDQLLFQVPDEVIIPIGCGTNMTAY
CCCEEEEEECCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
YKGFCEYKELGFINSLPKLTGVQSTEADTLARAYQKNQNRIEPLKTANTIATAIAVPYPI
HHHHHHHHHCCCHHCCCHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCC
DGDKAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIAHLLKKYEEGKLQKGS
CCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCC
TVVCVLSGEGLKDPGVVLISYSTTNYISFRNRF
EEEEEEECCCCCCCCEEEEEECCCEEEEEECCC
>Mature Secondary Structure 
PIKDPSSFVSLRESATPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKE
CCCCCHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCEEEEEEHHH
LGAKGIVLASTGNMAASCACYAAAAKMPCFIIVPEGVAASKLAQVMSYGGKIVQVKGSYN
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
EDAKLAYDIAKSKDFFLAGDYAFRVEGQKTAAFELIDQLLFQVPDEVIIPIGCGTNMTAY
CCCEEEEEECCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
YKGFCEYKELGFINSLPKLTGVQSTEADTLARAYQKNQNRIEPLKTANTIATAIAVPYPI
HHHHHHHHHCCCHHCCCHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCC
DGDKAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIAHLLKKYEEGKLQKGS
CCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCC
TVVCVLSGEGLKDPGVVLISYSTTNYISFRNRF
EEEEEEECCCCCCCCEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]