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The map label for this gene is dtpA [H]

Identifier: 134302044

GI number: 134302044

Start: 1017626

End: 1019173

Strand: Reverse

Name: dtpA [H]

Synonym: FTW_1078

Alternate gene names: 134302044

Gene position: 1019173-1017626 (Counterclockwise)

Preceding gene: 134302052

Following gene: 134302043

Centisome position: 53.68

GC content: 28.42

Gene sequence:

>1548_bases
GTGTTAAAAAGTACAAAATTTGCTAAATTTTTATTTTTATCTCGCAAAAAAGACATTAGTATAAAATTAAATACTATGTT
TAAGGATCTAAAATCAAAACAAAGTTTCACAATCGCAGCAATTACATTTTGGGGACAATTTGCAACTTATAGTTTCAATG
CTATTTTAATCTTATACTTGACGAGATCTGTATTAGATTATGGTATTGGCTTTTCAGAAAGTCATGCTTATTCATTTCAA
GGTATTTACAAGGCAATGAATTACGCAATTATTATGTTCGGTGGATATATTGCTGATAGATATTTAGGTTTAAGAAGATC
TATATTTTGGGGAAGTCTATTATTAGCTTTTGCATATTTAGCTGTATTTTTAAGTGGCTTTATGGTCCATTTTAGTGATG
AGTTTTTTATTTTTGCATTTGCTTTAGTTCCTGTATGCAGATCTTTACAGCTAGGAACAGCATCTGCAATGGTATCAAAA
ATATATAGCGATAATCCAGTACATGCAAAAAGTGGTATGACAATGTTTTATATATCTATTAATTTGGGTAGCTTACTAGC
CTATTTAGTAGCTCCTTCATTAATTGGATATCAATTTGGTGCTTTAGCAGTGTTAAGTGTAGTTTTTATTGGTAAATTAT
TAGCAATAATAAATTTTTCGTATAGATATAAGATTTATGACAACGTTGTTGATGAAATTGATAAAAAGCCAATGACAAGT
ATAGCTAAGAAAGTTGTTTTAGGATATCTAGCTATAGTATATGTTTTTACAGTAATTTGTTATCACTATCCAGACTATGC
AAATGTAGTTGTGGCAGTTATTAGTATGTTTTGTTTGCTATTATTTTTATTAAGAACAATATTTTTCTTAAAAGATGATG
TACGTATTAAGCAAATAGTTGGTTTGATATTAATAGTCGTAGCTGTAGTATTTTTTGTTATCTACAATCAAATGGAATCT
ACTCTTGTCATGGCAGCAAAGAATAATTCAGATCTTTTAATGTTTGGTTTTAAAGTTAATGCTGCGAGCTATCAGATAGT
TAACCCAATTTTGATAATATTTGGTGGTATGCTTTTAATAAGGATATATCCAATGTTTCCGAGATTTTATATACCATATC
AATTTGCTGTAGGAGTATTATTAGCAGCTGCAGGTTTATTCATAATGTATTATGGCTTCTCTATAGACAACAATGGTATT
GTAAGTGGTAATTACATTACATTATCTTATGTCCTAATTTCTATTTCAGAATTATTTGTAAGTGCTATTGGACTTAGTAT
GATCGGCATATACTGTGATAGTAAAACTATTGGTTTTGCAATGGGAGCATGGTATATATCCTCTTCTATGGCAAATTCTA
TAACAGGTCTATTAAATCAAGTGGTTGCTCTTCCTAAAGATGGAGTTAGTGCTTTAGAAAGCGCTAATATGTATAAAACT
TATTTCTTTGATACTAGTTTAAGTGTTATGTTAATTGGAATTTTAGTACTAATTTTAGCATACTTCTTAATAAAATTTAT
GAAAATAAGAAATATAGATTTTGTATAA

Upstream 100 bases:

>100_bases
ATATAGATATATTTTCATAATATTTCACATATTCATTAATTATTGCGTTAATTATATCATTTCTTGAGATTAGATAAACT
TGTTTAAGCAATCAACTATT

Downstream 100 bases:

>100_bases
AATTATAAACTAGGAGCATTAAAGTTTCTTTTGGCAGCTTCTTGATCTAGTAGATATAAACCACTATCTTTGACAAGTTT
GATTTTATTAATCATATCGC

Product: amino acid/peptide transporter (peptide:H+ symporter)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MLKSTKFAKFLFLSRKKDISIKLNTMFKDLKSKQSFTIAAITFWGQFATYSFNAILILYLTRSVLDYGIGFSESHAYSFQ
GIYKAMNYAIIMFGGYIADRYLGLRRSIFWGSLLLAFAYLAVFLSGFMVHFSDEFFIFAFALVPVCRSLQLGTASAMVSK
IYSDNPVHAKSGMTMFYISINLGSLLAYLVAPSLIGYQFGALAVLSVVFIGKLLAIINFSYRYKIYDNVVDEIDKKPMTS
IAKKVVLGYLAIVYVFTVICYHYPDYANVVVAVISMFCLLLFLLRTIFFLKDDVRIKQIVGLILIVVAVVFFVIYNQMES
TLVMAAKNNSDLLMFGFKVNAASYQIVNPILIIFGGMLLIRIYPMFPRFYIPYQFAVGVLLAAAGLFIMYYGFSIDNNGI
VSGNYITLSYVLISISELFVSAIGLSMIGIYCDSKTIGFAMGAWYISSSMANSITGLLNQVVALPKDGVSALESANMYKT
YFFDTSLSVMLIGILVLILAYFLIKFMKIRNIDFV

Sequences:

>Translated_515_residues
MLKSTKFAKFLFLSRKKDISIKLNTMFKDLKSKQSFTIAAITFWGQFATYSFNAILILYLTRSVLDYGIGFSESHAYSFQ
GIYKAMNYAIIMFGGYIADRYLGLRRSIFWGSLLLAFAYLAVFLSGFMVHFSDEFFIFAFALVPVCRSLQLGTASAMVSK
IYSDNPVHAKSGMTMFYISINLGSLLAYLVAPSLIGYQFGALAVLSVVFIGKLLAIINFSYRYKIYDNVVDEIDKKPMTS
IAKKVVLGYLAIVYVFTVICYHYPDYANVVVAVISMFCLLLFLLRTIFFLKDDVRIKQIVGLILIVVAVVFFVIYNQMES
TLVMAAKNNSDLLMFGFKVNAASYQIVNPILIIFGGMLLIRIYPMFPRFYIPYQFAVGVLLAAAGLFIMYYGFSIDNNGI
VSGNYITLSYVLISISELFVSAIGLSMIGIYCDSKTIGFAMGAWYISSSMANSITGLLNQVVALPKDGVSALESANMYKT
YFFDTSLSVMLIGILVLILAYFLIKFMKIRNIDFV
>Mature_515_residues
MLKSTKFAKFLFLSRKKDISIKLNTMFKDLKSKQSFTIAAITFWGQFATYSFNAILILYLTRSVLDYGIGFSESHAYSFQ
GIYKAMNYAIIMFGGYIADRYLGLRRSIFWGSLLLAFAYLAVFLSGFMVHFSDEFFIFAFALVPVCRSLQLGTASAMVSK
IYSDNPVHAKSGMTMFYISINLGSLLAYLVAPSLIGYQFGALAVLSVVFIGKLLAIINFSYRYKIYDNVVDEIDKKPMTS
IAKKVVLGYLAIVYVFTVICYHYPDYANVVVAVISMFCLLLFLLRTIFFLKDDVRIKQIVGLILIVVAVVFFVIYNQMES
TLVMAAKNNSDLLMFGFKVNAASYQIVNPILIIFGGMLLIRIYPMFPRFYIPYQFAVGVLLAAAGLFIMYYGFSIDNNGI
VSGNYITLSYVLISISELFVSAIGLSMIGIYCDSKTIGFAMGAWYISSSMANSITGLLNQVVALPKDGVSALESANMYKT
YFFDTSLSVMLIGILVLILAYFLIKFMKIRNIDFV

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=492, Percent_Identity=27.6422764227642, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1789911, Length=485, Percent_Identity=27.8350515463918, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1790572, Length=447, Percent_Identity=24.3847874720358, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786927, Length=515, Percent_Identity=22.1359223300971, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 57757; Mature: 57757

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSTKFAKFLFLSRKKDISIKLNTMFKDLKSKQSFTIAAITFWGQFATYSFNAILILYL
CCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHH
TRSVLDYGIGFSESHAYSFQGIYKAMNYAIIMFGGYIADRYLGLRRSIFWGSLLLAFAYL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFLSGFMVHFSDEFFIFAFALVPVCRSLQLGTASAMVSKIYSDNPVHAKSGMTMFYISI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
NLGSLLAYLVAPSLIGYQFGALAVLSVVFIGKLLAIINFSYRYKIYDNVVDEIDKKPMTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCHHHH
IAKKVVLGYLAIVYVFTVICYHYPDYANVVVAVISMFCLLLFLLRTIFFLKDDVRIKQIV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GLILIVVAVVFFVIYNQMESTLVMAAKNNSDLLMFGFKVNAASYQIVNPILIIFGGMLLI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
RIYPMFPRFYIPYQFAVGVLLAAAGLFIMYYGFSIDNNGIVSGNYITLSYVLISISELFV
HHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCEEECCCCEEECCHHHHHHHHHHHHHHHH
SAIGLSMIGIYCDSKTIGFAMGAWYISSSMANSITGLLNQVVALPKDGVSALESANMYKT
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEE
YFFDTSLSVMLIGILVLILAYFLIKFMKIRNIDFV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKSTKFAKFLFLSRKKDISIKLNTMFKDLKSKQSFTIAAITFWGQFATYSFNAILILYL
CCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHH
TRSVLDYGIGFSESHAYSFQGIYKAMNYAIIMFGGYIADRYLGLRRSIFWGSLLLAFAYL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFLSGFMVHFSDEFFIFAFALVPVCRSLQLGTASAMVSKIYSDNPVHAKSGMTMFYISI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
NLGSLLAYLVAPSLIGYQFGALAVLSVVFIGKLLAIINFSYRYKIYDNVVDEIDKKPMTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCHHHH
IAKKVVLGYLAIVYVFTVICYHYPDYANVVVAVISMFCLLLFLLRTIFFLKDDVRIKQIV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GLILIVVAVVFFVIYNQMESTLVMAAKNNSDLLMFGFKVNAASYQIVNPILIIFGGMLLI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
RIYPMFPRFYIPYQFAVGVLLAAAGLFIMYYGFSIDNNGIVSGNYITLSYVLISISELFV
HHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCEEECCCCEEECCHHHHHHHHHHHHHHHH
SAIGLSMIGIYCDSKTIGFAMGAWYISSSMANSITGLLNQVVALPKDGVSALESANMYKT
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEE
YFFDTSLSVMLIGILVLILAYFLIKFMKIRNIDFV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]