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The map label for this gene is ruvC

Identifier: 134302040

GI number: 134302040

Start: 1013871

End: 1014386

Strand: Reverse

Name: ruvC

Synonym: FTW_1072

Alternate gene names: 134302040

Gene position: 1014386-1013871 (Counterclockwise)

Preceding gene: 134302041

Following gene: 134302039

Centisome position: 53.43

GC content: 37.02

Gene sequence:

>516_bases
ATGGTTATTTTAGGAATAGATCCAGGCTCAAGGATAACAGGTTTTGGGGTTATAAAAGTCCAAGATAATAAAATCTATTA
TGTTGCAAGTGGCTGTATTCGGATAACAGAAATAACTACTCCAAAAAGACTCAAACAAATTGCTGATGGTATAACACAGA
TTATAAATATATACGCACCAACTGAAGCTGCGATTGAACAAATATTTATGTTTCAGAACCCTATGGGAGCTATTAAGTTA
GGACAAGCTAGAGGTGTAGCAATGTGTACACTAGCTATTAATAACCTAGAAGTTAGCGAATATTCAGCAAAACAAATTAA
ACAAGCTGTAGTAGGTACTGGAGGAGCTGCTAAATCTCAGGTCCAGCACATGGTTCAGTCTTTGTTAGGTTTGAGCAAAA
AGCCTCCAGAGGATGCTGCGGATGCTTTAGCAATAGCAATATGCCACTACCATAGTAGCAAATCATTGGCAAAAATCTCT
GGAGCAAGTCGAGTTTCACAAAAAAGAATTAAATGA

Upstream 100 bases:

>100_bases
TTAGAATTTCATATTTGACTATCAGTGTTGATGGTTTTCTATATATTGGTGTTAATCTATAGTAAAATCTTGTAGTCATA
GGGTTATAACAAAGTATTAT

Downstream 100 bases:

>100_bases
AATATCAAAAAAATCATTTATCTAAGTTTGATGTCAAACTTATAATAGCCTTATCATAAAAATTTACCAGTATTGTTTTA
TATGGGCACAAAGTATTACA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKL
GQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKIS
GASRVSQKRIK

Sequences:

>Translated_171_residues
MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKL
GQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKIS
GASRVSQKRIK
>Mature_171_residues
MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKL
GQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKIS
GASRVSQKRIK

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=168, Percent_Identity=52.9761904761905, Blast_Score=146, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_FRAT1 (Q14IH0)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666806.1
- ProteinModelPortal:   Q14IH0
- SMR:   Q14IH0
- STRING:   Q14IH0
- GeneID:   4198967
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0656
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- ProtClustDB:   PRK00039
- BioCyc:   FTUL393115:FTF0656-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18298; Mature: 18298

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAP
CEEEEECCCCCEEEEEEEEEECCEEEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHCCC
TEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQ
CHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHH
VQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAP
CEEEEECCCCCEEEEEEEEEECCEEEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHCCC
TEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQ
CHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHH
VQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA