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The map label for this gene is serC [H]

Identifier: 134301964

GI number: 134301964

Start: 936122

End: 937174

Strand: Direct

Name: serC [H]

Synonym: FTW_0980

Alternate gene names: 134301964

Gene position: 936122-937174 (Clockwise)

Preceding gene: 134301963

Following gene: 134301965

Centisome position: 49.31

GC content: 31.15

Gene sequence:

>1053_bases
ATGAAAATCAATTTTTGTGCAGGCCCTGCGGTTGTACCTACATCGATAATACAACAACTACAACAAATGATGACAAATTA
TAAAGATACTGGAGTATCATTATTATCGATTTCTCACCGTGATAAAGTTTTTGATGAAGTTCACGCTTCTATTCAGAAAA
ATTTAAGAAGTTTACTTAGTATTCCTGATAATTATGCTGTACTGTTAATGCAAGCGGGTGCTACTGCGCAATTTGCTGCT
ATTCCGCTAAACTTGGCTGATAAGCACAATAAAGCATTATATGTATGTAGTGGTCAATGGTCAGAAAAAGCAGCTCAAGA
AGCAGCTAAATTTATCGATGTTGATGCTGTCAAATATGATGATAATATCGCACAAAAATTCCAAGCGAATAAATATGATT
ATATATACTACACAGATAATGAAACAGTAGATGGATTTCAAATTAATAAACTAGCTAAATCATGTAATACCGAGTTAGTT
TGTGATGTGTCATCAAGCTTTTTATCAAAGCCTATTAATATTTCAGATTATGGACTTATTTATGCTGGAGCACAAAAAAA
TGCTGGAATACCAGGTTTGACTATAGTCATAATAAAAGATTCATTGATTAAAGAAAAACAAAATATTCCTGTAGTGTTTG
ACTATCTCGCAATGAAAAAGTCAAATTCAGTTTATAATACTCCATCTGTAATTTCATGGGTAACGTTCGAGTTAACTCTA
GAATATTTAATTGAAAAATTTGCTAATCTAGATAATGTTGAAGAGTTTAGCAATCAGAAAGCTAATTTACTTTATTCAGC
TATTGATAACTCAAAAATATATAAAAATGATATCAAACCTGAATATCGTTCAAATATGAATATAATCTTTCATTTACCTA
CACAAGAACTAACAGATAAATTTCTAAGCAATGCTAGTAAAGCAGGCTTCTATGGTCTTAAAGGACATCGAAGTGTAGGA
GGCTGTAGAGCAAGTCTATATAATGCAGTAAGTCTAGAAGATGTCAAAAAACTTGTACAGTTTATGCAGGAATTTGAGAA
TGAACAATTCTAA

Upstream 100 bases:

>100_bases
ATTGCTCTTCTTTTCAACTTTACTAATATTTTGTTTATATCAAATGGATTAAGTCTGATAAAATATACTTAAATTTGTAT
ATTAGAGATTATTTTTAATT

Downstream 100 bases:

>100_bases
GATTATTACAATTGATGGACCAAGCGGCGTTGGTAAAGGTACTTTAGCGAAGGCTCTAGCAAAATACTACGACTTTAAAC
TATTAGATAGCGGCGCCATT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKINFCAGPAVVPTSIIQQLQQMMTNYKDTGVSLLSISHRDKVFDEVHASIQKNLRSLLSIPDNYAVLLMQAGATAQFAA
IPLNLADKHNKALYVCSGQWSEKAAQEAAKFIDVDAVKYDDNIAQKFQANKYDYIYYTDNETVDGFQINKLAKSCNTELV
CDVSSSFLSKPINISDYGLIYAGAQKNAGIPGLTIVIIKDSLIKEKQNIPVVFDYLAMKKSNSVYNTPSVISWVTFELTL
EYLIEKFANLDNVEEFSNQKANLLYSAIDNSKIYKNDIKPEYRSNMNIIFHLPTQELTDKFLSNASKAGFYGLKGHRSVG
GCRASLYNAVSLEDVKKLVQFMQEFENEQF

Sequences:

>Translated_350_residues
MKINFCAGPAVVPTSIIQQLQQMMTNYKDTGVSLLSISHRDKVFDEVHASIQKNLRSLLSIPDNYAVLLMQAGATAQFAA
IPLNLADKHNKALYVCSGQWSEKAAQEAAKFIDVDAVKYDDNIAQKFQANKYDYIYYTDNETVDGFQINKLAKSCNTELV
CDVSSSFLSKPINISDYGLIYAGAQKNAGIPGLTIVIIKDSLIKEKQNIPVVFDYLAMKKSNSVYNTPSVISWVTFELTL
EYLIEKFANLDNVEEFSNQKANLLYSAIDNSKIYKNDIKPEYRSNMNIIFHLPTQELTDKFLSNASKAGFYGLKGHRSVG
GCRASLYNAVSLEDVKKLVQFMQEFENEQF
>Mature_350_residues
MKINFCAGPAVVPTSIIQQLQQMMTNYKDTGVSLLSISHRDKVFDEVHASIQKNLRSLLSIPDNYAVLLMQAGATAQFAA
IPLNLADKHNKALYVCSGQWSEKAAQEAAKFIDVDAVKYDDNIAQKFQANKYDYIYYTDNETVDGFQINKLAKSCNTELV
CDVSSSFLSKPINISDYGLIYAGAQKNAGIPGLTIVIIKDSLIKEKQNIPVVFDYLAMKKSNSVYNTPSVISWVTFELTL
EYLIEKFANLDNVEEFSNQKANLLYSAIDNSKIYKNDIKPEYRSNMNIIFHLPTQELTDKFLSNASKAGFYGLKGHRSVG
GCRASLYNAVSLEDVKKLVQFMQEFENEQF

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=359, Percent_Identity=39.8328690807799, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI10863955, Length=354, Percent_Identity=36.4406779661017, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=39.1061452513966, Blast_Score=268, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17506897, Length=359, Percent_Identity=42.3398328690808, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6324758, Length=382, Percent_Identity=36.9109947643979, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21356589, Length=360, Percent_Identity=39.4444444444444, Blast_Score=255, Evalue=3e-68,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39288; Mature: 39288

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINFCAGPAVVPTSIIQQLQQMMTNYKDTGVSLLSISHRDKVFDEVHASIQKNLRSLLS
CEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHC
IPDNYAVLLMQAGATAQFAAIPLNLADKHNKALYVCSGQWSEKAAQEAAKFIDVDAVKYD
CCCCEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECC
DNIAQKFQANKYDYIYYTDNETVDGFQINKLAKSCNTELVCDVSSSFLSKPINISDYGLI
CHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCEEE
YAGAQKNAGIPGLTIVIIKDSLIKEKQNIPVVFDYLAMKKSNSVYNTPSVISWVTFELTL
EECCCCCCCCCCEEEEEEECHHHHHCCCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
EYLIEKFANLDNVEEFSNQKANLLYSAIDNSKIYKNDIKPEYRSNMNIIFHLPTQELTDK
HHHHHHHCCCCCHHHHCCCHHHEEEEECCCCCEECCCCCHHHHCCCEEEEECCHHHHHHH
FLSNASKAGFYGLKGHRSVGGCRASLYNAVSLEDVKKLVQFMQEFENEQF
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKINFCAGPAVVPTSIIQQLQQMMTNYKDTGVSLLSISHRDKVFDEVHASIQKNLRSLLS
CEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHC
IPDNYAVLLMQAGATAQFAAIPLNLADKHNKALYVCSGQWSEKAAQEAAKFIDVDAVKYD
CCCCEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECC
DNIAQKFQANKYDYIYYTDNETVDGFQINKLAKSCNTELVCDVSSSFLSKPINISDYGLI
CHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCEEE
YAGAQKNAGIPGLTIVIIKDSLIKEKQNIPVVFDYLAMKKSNSVYNTPSVISWVTFELTL
EECCCCCCCCCCEEEEEEECHHHHHCCCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
EYLIEKFANLDNVEEFSNQKANLLYSAIDNSKIYKNDIKPEYRSNMNIIFHLPTQELTDK
HHHHHHHCCCCCHHHHCCCHHHEEEEECCCCCEECCCCCHHHHCCCEEEEECCHHHHHHH
FLSNASKAGFYGLKGHRSVGGCRASLYNAVSLEDVKKLVQFMQEFENEQF
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA