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The map label for this gene is mdaB [H]

Identifier: 134301869

GI number: 134301869

Start: 833732

End: 834322

Strand: Direct

Name: mdaB [H]

Synonym: FTW_0860

Alternate gene names: 134301869

Gene position: 833732-834322 (Clockwise)

Preceding gene: 134301868

Following gene: 134301870

Centisome position: 43.92

GC content: 32.32

Gene sequence:

>591_bases
ATGAAAAAAATATTATTAATTAATGGTAAAAAGGAATTTGGGCATTCAAAAGGTGCTTTGAATCAATATCTAAATGATAT
CGCTTATGATCATCTAAAAAGCTTAGGTCATGATGTTAAATTAACTATTGTTGATGATGATTATAATATTGATGATGAAA
TTCAGAAGTGGTTATGGGCAGATACTATAATTTATCAAATGCCAGGTTGGTGGATGGGACCACCTTGGATTATTAAAAAA
TATATCGATGAAGTATTCACTACAGGTCATGGTGTTATGTATGCTAGTGATGGTCGATCTAGGTATGATACTAGCAAAAA
ATATGGCTCTGGTGGTTTACTTCAGGGTAAAACTTATATGCTGTCGCTAACATGGAATGCTCCATTCGAGGCTTTTGTTG
AGAAAGATCAGCTTTTTGAAGGTGTTGGGGTTGATGGAGTGTATCTACATTTTCATAAAGCACATGAATTCATAGGTATG
AAAGGGTTACCAACATTTATTGCTAATGATGTTATGAAAAATCCTCTTATCAACGAATTTACGTTAAGTTATAAAAATCA
TTTAGATACAGTTTTTAGAAATGCAAGGTAG

Upstream 100 bases:

>100_bases
CTAACTCTGCCTTATGGCGGTGTTGTAATTAGTATTCATAATACTGGTGCAGTCTGTCAAGGAAGCCAGTTAATGAATCT
AGCTATAATATAGGAAAAAT

Downstream 100 bases:

>100_bases
TTTTGAAAAAATTAGTATTTGAATGATTAAACTATTTTGGTATGGTGTATTATTTATGTAAAAGTTACATGAGCTTTAGA
TAATTAACAGGAGTAATTTT

Product: flavodoxin-like fold family protein

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKKILLINGKKEFGHSKGALNQYLNDIAYDHLKSLGHDVKLTIVDDDYNIDDEIQKWLWADTIIYQMPGWWMGPPWIIKK
YIDEVFTTGHGVMYASDGRSRYDTSKKYGSGGLLQGKTYMLSLTWNAPFEAFVEKDQLFEGVGVDGVYLHFHKAHEFIGM
KGLPTFIANDVMKNPLINEFTLSYKNHLDTVFRNAR

Sequences:

>Translated_196_residues
MKKILLINGKKEFGHSKGALNQYLNDIAYDHLKSLGHDVKLTIVDDDYNIDDEIQKWLWADTIIYQMPGWWMGPPWIIKK
YIDEVFTTGHGVMYASDGRSRYDTSKKYGSGGLLQGKTYMLSLTWNAPFEAFVEKDQLFEGVGVDGVYLHFHKAHEFIGM
KGLPTFIANDVMKNPLINEFTLSYKNHLDTVFRNAR
>Mature_196_residues
MKKILLINGKKEFGHSKGALNQYLNDIAYDHLKSLGHDVKLTIVDDDYNIDDEIQKWLWADTIIYQMPGWWMGPPWIIKK
YIDEVFTTGHGVMYASDGRSRYDTSKKYGSGGLLQGKTYMLSLTWNAPFEAFVEKDQLFEGVGVDGVYLHFHKAHEFIGM
KGLPTFIANDVMKNPLINEFTLSYKNHLDTVFRNAR

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=192, Percent_Identity=63.5416666666667, Blast_Score=266, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 22575; Mature: 22575

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLINGKKEFGHSKGALNQYLNDIAYDHLKSLGHDVKLTIVDDDYNIDDEIQKWLWA
CCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
DTIIYQMPGWWMGPPWIIKKYIDEVFTTGHGVMYASDGRSRYDTSKKYGSGGLLQGKTYM
HHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCEEECCEEE
LSLTWNAPFEAFVEKDQLFEGVGVDGVYLHFHKAHEFIGMKGLPTFIANDVMKNPLINEF
EEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHCCCCHHH
TLSYKNHLDTVFRNAR
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKILLINGKKEFGHSKGALNQYLNDIAYDHLKSLGHDVKLTIVDDDYNIDDEIQKWLWA
CCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
DTIIYQMPGWWMGPPWIIKKYIDEVFTTGHGVMYASDGRSRYDTSKKYGSGGLLQGKTYM
HHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCEEECCEEE
LSLTWNAPFEAFVEKDQLFEGVGVDGVYLHFHKAHEFIGMKGLPTFIANDVMKNPLINEF
EEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHCCCCHHH
TLSYKNHLDTVFRNAR
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]