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The map label for this gene is lysA [H]

Identifier: 134301797

GI number: 134301797

Start: 747912

End: 749096

Strand: Direct

Name: lysA [H]

Synonym: FTW_0770

Alternate gene names: 134301797

Gene position: 747912-749096 (Clockwise)

Preceding gene: 134301796

Following gene: 134301798

Centisome position: 39.4

GC content: 31.81

Gene sequence:

>1185_bases
ATGAATAAGTATATAATTTTTGATAATACAAAACTACTTGAATATATAGGTAAGAATTCTCTTATAACCCCATGTTATAT
CTATGATTTAGAGCTTTTAGAAGATACATTTTTAAATGCAAAAAAATCATTAGATAAAAATTTCAAAAATGCTGAGATTC
ATTATGCAATCAAGGCAAATCATAATCCTAAGATAGTAGGTATCGCCAAGAAGTATGGTATGGGGATTGATTGTGTAAGT
GGTGGTGAAATTAAAAGGGCGCTAGAGCAGAAGGTAGATTCTCAGCATATTGTTTTTGCTGGAGTTGGTAAGGCTGACTG
GGAAATTGAGTTAGCTATAGATAATGATATTTTTGCATTTAATAGCGAGTCTTTAGAAGAAATACAAGTCATTAATCAAA
TAGCTCAGCGTAAAAATAAACAAGTTAATATTTGTCTACGCGTCAATCCAAATATAGATGCACAGACTCATCATTATATA
AGTACAGGTCAATTCGACGACAAGTTCGGTATTGCTTTTGTTAATATTCTTAATTGGTTAAAAGATGAATATCGTAACTT
TGCTAATATAAACATAATAGGATTACATTATCATGTTGGCTCACAGATATTGAATTATCAGGTTTTTCAATCACTAGCCA
TTACAACAAACGAGCATATCAAGCTACTCAGGCAAAATGATATTAATATCAAACATATTAATTTTGGTGGAGGTTTGGGA
ATTGATTATCAAAATCCACAGCAGAATCCTATTGTAGACTTTGACGGGTATTTTGCCAGGTTTAGAGAGTTTTTTGAATA
TTGTGATGAGCTTACATTACATTTTGAGCTTGGTAGATCATTGGTGGGACAATCTGGAGTGCTAGTATCTCAAGTATTGT
TTAATAAAGTAACTCAAGGCACACATTTTGTGATTATAGATGCTGGTATGACGGAGCTTATTAGACCAGCGCTTTATCAA
GCACAACATAAAATAGCAGCTTTAATTGATGAGAATATTAATCAAAAACAACATTATCATATAGTTGGACCTATTTGTGA
ATCAAGTGATGTATTTGCAAAATATTATCAACTACCTAAACTAAAACGTGGTGATCTATTAGCTATATATTCAGCAGGTG
CGTACGGAAAGGTTTTGGCTAGTGAATATAATCTAAGACCAAGTGTTCAAGAGTATTTTATATAG

Upstream 100 bases:

>100_bases
TTCAAATAAAAATCCAGTGTTAGTACAACTACCACAACATATCTATCATCAAGTTAAAGATGATTGGCAATTACCTGATT
TATTATAAAGGTATAAATTA

Downstream 100 bases:

>100_bases
GGTTACAGACAATGCATATATCTAACAAAAAAATTTCGACATTATCGCTAACAATGCTAAATATTTCAGCGATAATTAGT
CTAAGCTCGATTGCTTATAT

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNKYIIFDNTKLLEYIGKNSLITPCYIYDLELLEDTFLNAKKSLDKNFKNAEIHYAIKANHNPKIVGIAKKYGMGIDCVS
GGEIKRALEQKVDSQHIVFAGVGKADWEIELAIDNDIFAFNSESLEEIQVINQIAQRKNKQVNICLRVNPNIDAQTHHYI
STGQFDDKFGIAFVNILNWLKDEYRNFANINIIGLHYHVGSQILNYQVFQSLAITTNEHIKLLRQNDINIKHINFGGGLG
IDYQNPQQNPIVDFDGYFARFREFFEYCDELTLHFELGRSLVGQSGVLVSQVLFNKVTQGTHFVIIDAGMTELIRPALYQ
AQHKIAALIDENINQKQHYHIVGPICESSDVFAKYYQLPKLKRGDLLAIYSAGAYGKVLASEYNLRPSVQEYFI

Sequences:

>Translated_394_residues
MNKYIIFDNTKLLEYIGKNSLITPCYIYDLELLEDTFLNAKKSLDKNFKNAEIHYAIKANHNPKIVGIAKKYGMGIDCVS
GGEIKRALEQKVDSQHIVFAGVGKADWEIELAIDNDIFAFNSESLEEIQVINQIAQRKNKQVNICLRVNPNIDAQTHHYI
STGQFDDKFGIAFVNILNWLKDEYRNFANINIIGLHYHVGSQILNYQVFQSLAITTNEHIKLLRQNDINIKHINFGGGLG
IDYQNPQQNPIVDFDGYFARFREFFEYCDELTLHFELGRSLVGQSGVLVSQVLFNKVTQGTHFVIIDAGMTELIRPALYQ
AQHKIAALIDENINQKQHYHIVGPICESSDVFAKYYQLPKLKRGDLLAIYSAGAYGKVLASEYNLRPSVQEYFI
>Mature_394_residues
MNKYIIFDNTKLLEYIGKNSLITPCYIYDLELLEDTFLNAKKSLDKNFKNAEIHYAIKANHNPKIVGIAKKYGMGIDCVS
GGEIKRALEQKVDSQHIVFAGVGKADWEIELAIDNDIFAFNSESLEEIQVINQIAQRKNKQVNICLRVNPNIDAQTHHYI
STGQFDDKFGIAFVNILNWLKDEYRNFANINIIGLHYHVGSQILNYQVFQSLAITTNEHIKLLRQNDINIKHINFGGGLG
IDYQNPQQNPIVDFDGYFARFREFFEYCDELTLHFELGRSLVGQSGVLVSQVLFNKVTQGTHFVIIDAGMTELIRPALYQ
AQHKIAALIDENINQKQHYHIVGPICESSDVFAKYYQLPKLKRGDLLAIYSAGAYGKVLASEYNLRPSVQEYFI

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=394, Percent_Identity=29.9492385786802, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 44967; Mature: 44967

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYIIFDNTKLLEYIGKNSLITPCYIYDLELLEDTFLNAKKSLDKNFKNAEIHYAIKAN
CCCEEEECCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
HNPKIVGIAKKYGMGIDCVSGGEIKRALEQKVDSQHIVFAGVGKADWEIELAIDNDIFAF
CCCEEEEEHHHHCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCEEEE
NSESLEEIQVINQIAQRKNKQVNICLRVNPNIDAQTHHYISTGQFDDKFGIAFVNILNWL
CCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
KDEYRNFANINIIGLHYHVGSQILNYQVFQSLAITTNEHIKLLRQNDINIKHINFGGGLG
HHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHEEEECCCCEEEEEECCCCCC
IDYQNPQQNPIVDFDGYFARFREFFEYCDELTLHFELGRSLVGQSGVLVSQVLFNKVTQG
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHCCCCHHHHHHHHHHHCCC
THFVIIDAGMTELIRPALYQAQHKIAALIDENINQKQHYHIVGPICESSDVFAKYYQLPK
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCC
LKRGDLLAIYSAGAYGKVLASEYNLRPSVQEYFI
CCCCCEEEEEECCCCHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MNKYIIFDNTKLLEYIGKNSLITPCYIYDLELLEDTFLNAKKSLDKNFKNAEIHYAIKAN
CCCEEEECCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
HNPKIVGIAKKYGMGIDCVSGGEIKRALEQKVDSQHIVFAGVGKADWEIELAIDNDIFAF
CCCEEEEEHHHHCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCEEEE
NSESLEEIQVINQIAQRKNKQVNICLRVNPNIDAQTHHYISTGQFDDKFGIAFVNILNWL
CCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
KDEYRNFANINIIGLHYHVGSQILNYQVFQSLAITTNEHIKLLRQNDINIKHINFGGGLG
HHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHEEEECCCCEEEEEECCCCCC
IDYQNPQQNPIVDFDGYFARFREFFEYCDELTLHFELGRSLVGQSGVLVSQVLFNKVTQG
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHCCCCHHHHHHHHHHHCCC
THFVIIDAGMTELIRPALYQAQHKIAALIDENINQKQHYHIVGPICESSDVFAKYYQLPK
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCC
LKRGDLLAIYSAGAYGKVLASEYNLRPSVQEYFI
CCCCCEEEEEECCCCHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]