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The map label for this gene is yjjL [H]

Identifier: 134301789

GI number: 134301789

Start: 730334

End: 731557

Strand: Reverse

Name: yjjL [H]

Synonym: FTW_0757

Alternate gene names: 134301789

Gene position: 731557-730334 (Counterclockwise)

Preceding gene: 134301790

Following gene: 134301786

Centisome position: 38.53

GC content: 33.33

Gene sequence:

>1224_bases
ATGAAAAAATATTACTACAATACTTTAATAATTCTTTTACTGTTCTTTTTGGCATTACTAAATTATGTTGACAGATCAAC
TCTAAGTATAGCTAATACTGAAATAGCTAACGCTTTTAACATAACGCCAACAGAAATGGGGATATTACTATCCGCTTTCA
TGTGGTCATATGCTATTGCTAGTTTACCAGCAGGATATATGGTTGATCGTTTAGGTGTTAATAAAGTAATGTTAATAAGT
ATGATTGCATGGTCTGTAGCGTGTATATTAGGAGGTTTTGTAATAGGATTTTACTCAATCTTACTAACACGTATACTGCT
TGGTCTTGCTGAAGCTCCTTTTTTTATAGTAGCTACTAGGATAATCCAACATCGTTTTCCAAGCTCTCAAAGAGGACTTA
TGTCATCTATAATTGCTTTAGGGCCAAGATTAGCAAATATTCTTGCACCTTTAATATTAGTTGGCTTAATGCTATTAATA
GATTGGAGAGGTATGTTTATAATATTAGGTGTTGTAGGACTAATTGCTGCGATTGGCTGGAAGCTTCTACATACTAAAGA
AACACTAGAGCATACAACAACAATTATTAAAAAGTCTCAAAAGATTTCCATTTCCGAGACTCTAAGAAATAAAAACGTTG
TTTACTTATGTATCGGAAATCTATGTTCATCTTATGCCTACTGGCTATTTTTAACATGGCTGCCCTTCTATTTTATAAAA
GTAAAACATCTAACCCTCTCACAAATGAGTATTGCAACATCTGCTTCTTTTATTTCAGGAGTTGCTTCTGTAATGCTAGG
TGGGATTATCTCTGATTTTATGATAAAAAAGGGATATACTGCTGTCTTTGCACGTCTAACTCCTATAATTGCTGGATGCT
TAGTTGCGTCTATAGCGATCCTAGCATTACCATTTATTGATAATATTTTTGTTATCGTTTGTGTAATTGGCGTCACTATC
TTCTGCTTAGGACTAAGAATATCTCCAACATGGGCATTAGTTGCTGATATTTCTCCATACAGTTTAGTAGGAACAATTGG
TGGATTACAAAACTTTGCTAATTTTGTTGGCGCTGGGTTAGCCCCGCTTATTACAGGAATAATACTACAATCAACAAATG
ATAATTTTATGATTATATTTATATTCAGTGGAATTATTTGTCTATTCGGCTCAATAATATATATGCTCATTCGCGATAAA
CGAGCTCAAAATGAGACAATTTAG

Upstream 100 bases:

>100_bases
ATGGTTTTAGCTGCTGGAGATGGTAAAGGTATATATATACTTGAGCCACATGAGGGTGCTCAACCAGGTATGCGTGTCAA
ATAATATAAGCTCTCCCACA

Downstream 100 bases:

>100_bases
TGCACTGTAATTTTTATTTTGCCTTTGGTTATATTTTTAATTTCCTCTAAGAACATATCTTTATCAGATGCAACAATCTT
AATAATTTTAGAAATATTAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAFMWSYAIASLPAGYMVDRLGVNKVMLIS
MIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGLMSSIIALGPRLANILAPLILVGLMLLI
DWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNVVYLCIGNLCSSYAYWLFLTWLPFYFIK
VKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGCLVASIAILALPFIDNIFVIVCVIGVTI
FCLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTNDNFMIIFIFSGIICLFGSIIYMLIRDK
RAQNETI

Sequences:

>Translated_407_residues
MKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAFMWSYAIASLPAGYMVDRLGVNKVMLIS
MIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGLMSSIIALGPRLANILAPLILVGLMLLI
DWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNVVYLCIGNLCSSYAYWLFLTWLPFYFIK
VKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGCLVASIAILALPFIDNIFVIVCVIGVTI
FCLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTNDNFMIIFIFSGIICLFGSIIYMLIRDK
RAQNETI
>Mature_407_residues
MKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAFMWSYAIASLPAGYMVDRLGVNKVMLIS
MIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGLMSSIIALGPRLANILAPLILVGLMLLI
DWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNVVYLCIGNLCSSYAYWLFLTWLPFYFIK
VKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGCLVASIAILALPFIDNIFVIVCVIGVTI
FCLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTNDNFMIIFIFSGIICLFGSIIYMLIRDK
RAQNETI

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=388, Percent_Identity=23.4536082474227, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI148743791, Length=394, Percent_Identity=22.5888324873096, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI9966811, Length=285, Percent_Identity=23.1578947368421, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI185136021, Length=409, Percent_Identity=24.6943765281174, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21322234, Length=415, Percent_Identity=21.6867469879518, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI215490102, Length=133, Percent_Identity=33.0827067669173, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI215490096, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI14042968, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI2367379, Length=415, Percent_Identity=31.3253012048193, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082320, Length=411, Percent_Identity=27.2506082725061, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1789515, Length=426, Percent_Identity=28.8732394366197, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789152, Length=435, Percent_Identity=28.735632183908, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI2367193, Length=428, Percent_Identity=20.7943925233645, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=413, Percent_Identity=21.0653753026634, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193205400, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654039, Length=357, Percent_Identity=25.2100840336134, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17864456, Length=357, Percent_Identity=25.2100840336134, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573708, Length=404, Percent_Identity=20.2970297029703, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573707, Length=404, Percent_Identity=20.2970297029703, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580790, Length=372, Percent_Identity=23.6559139784946, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658658, Length=432, Percent_Identity=21.2962962962963, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654037, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654041, Length=346, Percent_Identity=23.121387283237, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654044, Length=231, Percent_Identity=25.5411255411255, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573299, Length=437, Percent_Identity=21.5102974828375, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44691; Mature: 44691

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAFMWSYAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
SLPAGYMVDRLGVNKVMLISMIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATR
HCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIQHRFPSSQRGLMSSIIALGPRLANILAPLILVGLMLLIDWRGMFIILGVVGLIAAIGW
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLHTKETLEHTTTIIKKSQKISISETLRNKNVVYLCIGNLCSSYAYWLFLTWLPFYFIK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
VKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGCLVASIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LALPFIDNIFVIVCVIGVTIFCLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
APLITGIILQSTNDNFMIIFIFSGIICLFGSIIYMLIRDKRAQNETI
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAFMWSYAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
SLPAGYMVDRLGVNKVMLISMIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATR
HCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIQHRFPSSQRGLMSSIIALGPRLANILAPLILVGLMLLIDWRGMFIILGVVGLIAAIGW
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLHTKETLEHTTTIIKKSQKISISETLRNKNVVYLCIGNLCSSYAYWLFLTWLPFYFIK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
VKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGCLVASIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LALPFIDNIFVIVCVIGVTIFCLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
APLITGIILQSTNDNFMIIFIFSGIICLFGSIIYMLIRDKRAQNETI
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]