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The map label for this gene is bsaA [H]

Identifier: 134301693

GI number: 134301693

Start: 627399

End: 627869

Strand: Direct

Name: bsaA [H]

Synonym: FTW_0638

Alternate gene names: 134301693

Gene position: 627399-627869 (Clockwise)

Preceding gene: 134301692

Following gene: 134301694

Centisome position: 33.05

GC content: 32.06

Gene sequence:

>471_bases
ATGTCTATTTATGACTTTAAGCTAACTGCAAATGATGGTTCAGAATATCATCTGCCTAAAAATAAAGTGCTTTTGATAGT
TAATGTTGCGAGTAAGTGCGGTTTTACTAAGCAGTATAGAGGTTTGCAACATTTACATAAAATATATCCAGATTTAGAAA
TTGTTGCATTCCCTTGTAATTCATTTGGTGGACAGGAGCCAGGTAGTGACGAAGAAATCAAGAATTTCTGTGAAACTAAT
TATAATGTCACATTTCCAATTATGAAAAAAACCAAAGTAAATGGTAAAGATGCTGAGCCATTGTTTGAGTATCTCAAAGA
AAGAGCAAAAGGAGTCTTAGGAACTGAAGCTATAAAGTGGAATTTTACTAAGTTTTTAGTATCAAAAGATGGCGAGACCA
TCGTAAGATATGCACCTAAAACTATTCCAGAAGATTTAATTCCAGATATTGATAATTTTCTAAAAGACTAA

Upstream 100 bases:

>100_bases
CCAAAGTTGGTTGCTGAAGTTTTTGATATTTTAAATAACAAAAATTTGCAACCAGCAGATCAAAGTTTTTAATAACAAGT
ATATAAGAGGTAAAAATAAC

Downstream 100 bases:

>100_bases
AACTAATATAATCAAACATTCATTTTTAAGAAATAAGCAATATGATAACTACTTCACTATCTTATATTTCATCACTACTT
TTGTTATCTAGTGTAATTGT

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSIYDFKLTANDGSEYHLPKNKVLLIVNVASKCGFTKQYRGLQHLHKIYPDLEIVAFPCNSFGGQEPGSDEEIKNFCETN
YNVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKWNFTKFLVSKDGETIVRYAPKTIPEDLIPDIDNFLKD

Sequences:

>Translated_156_residues
MSIYDFKLTANDGSEYHLPKNKVLLIVNVASKCGFTKQYRGLQHLHKIYPDLEIVAFPCNSFGGQEPGSDEEIKNFCETN
YNVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKWNFTKFLVSKDGETIVRYAPKTIPEDLIPDIDNFLKD
>Mature_155_residues
SIYDFKLTANDGSEYHLPKNKVLLIVNVASKCGFTKQYRGLQHLHKIYPDLEIVAFPCNSFGGQEPGSDEEIKNFCETNY
NVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKWNFTKFLVSKDGETIVRYAPKTIPEDLIPDIDNFLKD

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=160, Percent_Identity=44.375, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI90903240, Length=160, Percent_Identity=44.375, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=41.4012738853503, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=37.5, Blast_Score=106, Evalue=8e-24,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=33.5195530726257, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=32.4175824175824, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=33.5195530726257, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI33186887, Length=179, Percent_Identity=31.2849162011173, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=33.1521739130435, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788003, Length=159, Percent_Identity=43.3962264150943, Blast_Score=124, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17506887, Length=154, Percent_Identity=44.8051948051948, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17535473, Length=139, Percent_Identity=44.6043165467626, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=39.0243902439024, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=36.7088607594937, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=31.9018404907975, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=30.0613496932515, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=56.1151079136691, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=50.3184713375796, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322826, Length=137, Percent_Identity=46.7153284671533, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=44.375, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=44.375, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=44.375, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI85726443, Length=137, Percent_Identity=41.6058394160584, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17786; Mature: 17654

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYDFKLTANDGSEYHLPKNKVLLIVNVASKCGFTKQYRGLQHLHKIYPDLEIVAFPCN
CCEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
SFGGQEPGSDEEIKNFCETNYNVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKW
CCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHEEE
NFTKFLVSKDGETIVRYAPKTIPEDLIPDIDNFLKD
CCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SIYDFKLTANDGSEYHLPKNKVLLIVNVASKCGFTKQYRGLQHLHKIYPDLEIVAFPCN
CEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
SFGGQEPGSDEEIKNFCETNYNVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKW
CCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHEEE
NFTKFLVSKDGETIVRYAPKTIPEDLIPDIDNFLKD
CCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]