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The map label for this gene is glpX [H]

Identifier: 134301393

GI number: 134301393

Start: 287774

End: 288760

Strand: Direct

Name: glpX [H]

Synonym: FTW_0283

Alternate gene names: 134301393

Gene position: 287774-288760 (Clockwise)

Preceding gene: 134301392

Following gene: 134301394

Centisome position: 15.16

GC content: 40.02

Gene sequence:

>987_bases
ATGAATAGAAAAGTAGCACTTGAAGCAGTCAGAGTTACTGAGCTGGCAGCACTAGCATCATGGAGCCAGATGGGTAGAGG
TGATAAAATAGCAGCTGATCAAGCTGCCGTTGATGCGATGAGAAAGGCACTTAATGAAGTTGATATTGATGGAACTGTTG
TGATTGGTGAAGGTGAACTTGATGAGGCGCCAATGCTCTATATTGGTGAAAAAGTTGGTGCTGGTGGTTGCGAGGTTGAT
ATTGCTTTGGATCCTCTAGAGGGGACTACGATTACATCAAAGGGTGGCGCTAATGCCCTTACTGTTTTAGCTATGGCAGA
TAAAGGTGGTTTTTTAAATGCTCCTGATGTATATATGCAAAAGATTGCTGTTGGTGGTATTAATGCGCCTAAGGGTATAG
TTGATCTAGATGATTCTGTAACAAATAACCTAAAAAGAATTGCTGAATTTAAAGGTGTGCATATGTCTGCATTAGTTGTA
TGTACTATGGATAGACCTAGACATGAGCATATCATCAAGGAGGCACGTGAATGTGGTGCTAGGGTAATTCTAATAAATGA
TGGTGATGTATCTGGTGTAATAGCTACAGCAACCGAAAATTCTGGAATAGATGTGTATATCGGTACTGGTGGAGCACCTG
AAGGTGTTCTTGCTGCAGCCGCTCTTAAATGTTTAGGTGGTCAAATGCAAGCAAGATTGATATTCAATGATGAAGAAGAG
ATAAAACGCGCCCATCGTCTTGGTATTACTGATCTTAATAAAAAATATGATATTGATGATTTAGCATCTGGTGATATTGT
TTTTGCTGCAACTGGAGTGACTGATGGTAATATGCTTCAAGGAGTTAAACGTGTGAATAGTACACGTAGAGGTTCTTATG
CAGTTACACATAGTGTGGTTATGCGCTCTACAACAAAAACAGTCAGACATATCACCGCAGAGCACAGTTTTGACTTCAAA
GAGGGTATAGAAAAGTTTATGTCATAG

Upstream 100 bases:

>100_bases
GGACACTTTTTCCATGGTAAGCTTATAGAGCTTAAGACGGTAATAGAAAATTTTTTAACGCCAATAGTCGATAAACTTTA
AACAAAAAGGACCAAAATAA

Downstream 100 bases:

>100_bases
TTTAGACGATTTATTTTTAATTCTGATAAGTTTCCTAAGTATCTAATTATTTCCGCAAGCAGTTATCAGTAACTGTTATC
TAAACTCTATAAATTATCAA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVVIGEGELDEAPMLYIGEKVGAGGCEVD
IALDPLEGTTITSKGGANALTVLAMADKGGFLNAPDVYMQKIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVHMSALVV
CTMDRPRHEHIIKEARECGARVILINDGDVSGVIATATENSGIDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEE
IKRAHRLGITDLNKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVVMRSTTKTVRHITAEHSFDFK
EGIEKFMS

Sequences:

>Translated_328_residues
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVVIGEGELDEAPMLYIGEKVGAGGCEVD
IALDPLEGTTITSKGGANALTVLAMADKGGFLNAPDVYMQKIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVHMSALVV
CTMDRPRHEHIIKEARECGARVILINDGDVSGVIATATENSGIDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEE
IKRAHRLGITDLNKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVVMRSTTKTVRHITAEHSFDFK
EGIEKFMS
>Mature_328_residues
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVVIGEGELDEAPMLYIGEKVGAGGCEVD
IALDPLEGTTITSKGGANALTVLAMADKGGFLNAPDVYMQKIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVHMSALVV
CTMDRPRHEHIIKEARECGARVILINDGDVSGVIATATENSGIDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEE
IKRAHRLGITDLNKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVVMRSTTKTVRHITAEHSFDFK
EGIEKFMS

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=336, Percent_Identity=46.7261904761905, Blast_Score=283, Evalue=9e-78,
Organism=Escherichia coli, GI1789298, Length=326, Percent_Identity=42.9447852760736, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34814; Mature: 34814

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVVIGEGEL
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
DEAPMLYIGEKVGAGGCEVDIALDPLEGTTITSKGGANALTVLAMADKGGFLNAPDVYMQ
CCCCEEEEECCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCCCCCHHHHH
KIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVHMSALVVCTMDRPRHEHIIKEARECGA
HHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCC
RVILINDGDVSGVIATATENSGIDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEE
EEEEEECCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCHHH
IKRAHRLGITDLNKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVV
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHH
MRSTTKTVRHITAEHSFDFKEGIEKFMS
HHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVVIGEGEL
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
DEAPMLYIGEKVGAGGCEVDIALDPLEGTTITSKGGANALTVLAMADKGGFLNAPDVYMQ
CCCCEEEEECCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCCCCCHHHHH
KIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVHMSALVVCTMDRPRHEHIIKEARECGA
HHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCC
RVILINDGDVSGVIATATENSGIDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEE
EEEEEECCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCHHH
IKRAHRLGITDLNKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVV
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHH
MRSTTKTVRHITAEHSFDFKEGIEKFMS
HHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]