Click here to switch to the map view.

The map label for this gene is trkH [H]

Identifier: 134301386

GI number: 134301386

Start: 279331

End: 280785

Strand: Reverse

Name: trkH [H]

Synonym: FTW_0275

Alternate gene names: 134301386

Gene position: 280785-279331 (Counterclockwise)

Preceding gene: 134301388

Following gene: 134301379

Centisome position: 14.79

GC content: 33.88

Gene sequence:

>1455_bases
ATGATGTTAAGCCAGAAACCAAAAATAATTGGTATATTTTTAATGTTCCTTAGCCTTACCATGCTTAGTCCTTTATTGGT
TGACTATATATATGATGAAGATAATGCATATCCATTTGTGTTGAGTTTTACAGTAACATTTTTATGTGGTTTTTTGCTTT
GGTTTATTTCACGTAAATCAAATAAGAAACTATCAAATAGAGATGGTTTTCTTATAGTTACACTCGTTTGGATATTTGTA
ACAGTCTTTGGTGCAATACCATATATGTCTTTTCCTGGACTAAATCTATCCTTTACTAATGCAGTATTTGAGTCTGTTTC
TGGATTTACTACAACTGGTGGTACTGTGATTGAAGGACTTGATAAGCTTCCTCATAGCATTTTATTTTATCGACAACAAA
CTGAATTTTTCGGTGGCATGGGCATTATTGTTCTATCAGTAGCAATTCTACCTTTACTAGGTGTCGGTGGTATGCAGTTA
TATAAAGCGGAAGTATCAGGTCAATGGAAAGATGATAAAATCGCCCCTAAAATCTCCAGCACTGCCAAAGCACTTTGGAT
GGTATATCTATTACTTACTTTCTTATGCTTTATCTCTTATCTATTAGTTGGTGTAGAACCATTTGATGCGATATGCTATA
CATTCTCAACAGTATCAACTGGCGGTTTTGCGCCTTCGGATGCAAGCATGACAGATAAGCCATTAGGAATGCTTATTGTA
TGTGCAATCTTTCTTTTCTTAGGTGCTACTAGTTTTAAAGCCCATTATATAGCTCTGTCAAAATTTAAAATAAGTCATTA
TTTTAGAAATATCGAGTTTAAAGCATATTTTTACTTCTTATTTTTTACCTCATTTATTGTATGTATCACTATAATTGCAC
ATACAAATGACCTTTCAAATATTTTCTCAATAGTTACTAATAGCATTTTTCAAGTAATATCCATCAGCTCAAGTGCTGGC
TTTGTTTCTGATAATAACTATTACTTATGGCCTAGCTTCTTGCCAATTATGTTAATGTTTATTGCCATAATTGGTGGTTG
TGGTGGCTCTACCGCTGGTGGCTTAAAGATGATTAGAGCAATTTTATTTAAAGAAAAAGCTATACTTGAGGCTAAACGTG
TCATCCATCCACAAGGGGTTTTCACTGTTAAATTAGGTGATATCCATATATCAGAACAAGCTCTTAATAGAGTTTCTGGA
TTTATCTCTGTTTATATTATAATTTTTGCTGGTGGTTGGTTAGCCTTGCTAGGTTGCGGTCTAGATATCCCCACAGCATT
CTCAACAATTGCTACCACTTTGTCTAATGTGGGTCCGGGACTAGGTGATATTGGTTCAAATTTTAAAAATCTCCCTAAAG
AAGCTCTATGGATATGCAACTTTGCGATGATTGCAGGACGTCTTGAGATATTTACAATTCTAGTATTATTTATGCCAGAT
TTTTGGAGAAAATAA

Upstream 100 bases:

>100_bases
TCTTAAATACTAATTATAAATTATCTTGTAGCTTGTGAGTAATTATACTAAACTAAACATCAAAGTCACCCATAAACGTT
AAGCTTTAAAGCATTAGCAG

Downstream 100 bases:

>100_bases
ACACTTTAAATATATTAAAGACCCCCAGACTCAACCAAATAAGATAAGTTACCAACCCTATCATACTCAATAGCATTTGC
ATATGCGATAACTTTGTAAT

Product: cation efflux transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MMLSQKPKIIGIFLMFLSLTMLSPLLVDYIYDEDNAYPFVLSFTVTFLCGFLLWFISRKSNKKLSNRDGFLIVTLVWIFV
TVFGAIPYMSFPGLNLSFTNAVFESVSGFTTTGGTVIEGLDKLPHSILFYRQQTEFFGGMGIIVLSVAILPLLGVGGMQL
YKAEVSGQWKDDKIAPKISSTAKALWMVYLLLTFLCFISYLLVGVEPFDAICYTFSTVSTGGFAPSDASMTDKPLGMLIV
CAIFLFLGATSFKAHYIALSKFKISHYFRNIEFKAYFYFLFFTSFIVCITIIAHTNDLSNIFSIVTNSIFQVISISSSAG
FVSDNNYYLWPSFLPIMLMFIAIIGGCGGSTAGGLKMIRAILFKEKAILEAKRVIHPQGVFTVKLGDIHISEQALNRVSG
FISVYIIIFAGGWLALLGCGLDIPTAFSTIATTLSNVGPGLGDIGSNFKNLPKEALWICNFAMIAGRLEIFTILVLFMPD
FWRK

Sequences:

>Translated_484_residues
MMLSQKPKIIGIFLMFLSLTMLSPLLVDYIYDEDNAYPFVLSFTVTFLCGFLLWFISRKSNKKLSNRDGFLIVTLVWIFV
TVFGAIPYMSFPGLNLSFTNAVFESVSGFTTTGGTVIEGLDKLPHSILFYRQQTEFFGGMGIIVLSVAILPLLGVGGMQL
YKAEVSGQWKDDKIAPKISSTAKALWMVYLLLTFLCFISYLLVGVEPFDAICYTFSTVSTGGFAPSDASMTDKPLGMLIV
CAIFLFLGATSFKAHYIALSKFKISHYFRNIEFKAYFYFLFFTSFIVCITIIAHTNDLSNIFSIVTNSIFQVISISSSAG
FVSDNNYYLWPSFLPIMLMFIAIIGGCGGSTAGGLKMIRAILFKEKAILEAKRVIHPQGVFTVKLGDIHISEQALNRVSG
FISVYIIIFAGGWLALLGCGLDIPTAFSTIATTLSNVGPGLGDIGSNFKNLPKEALWICNFAMIAGRLEIFTILVLFMPD
FWRK
>Mature_484_residues
MMLSQKPKIIGIFLMFLSLTMLSPLLVDYIYDEDNAYPFVLSFTVTFLCGFLLWFISRKSNKKLSNRDGFLIVTLVWIFV
TVFGAIPYMSFPGLNLSFTNAVFESVSGFTTTGGTVIEGLDKLPHSILFYRQQTEFFGGMGIIVLSVAILPLLGVGGMQL
YKAEVSGQWKDDKIAPKISSTAKALWMVYLLLTFLCFISYLLVGVEPFDAICYTFSTVSTGGFAPSDASMTDKPLGMLIV
CAIFLFLGATSFKAHYIALSKFKISHYFRNIEFKAYFYFLFFTSFIVCITIIAHTNDLSNIFSIVTNSIFQVISISSSAG
FVSDNNYYLWPSFLPIMLMFIAIIGGCGGSTAGGLKMIRAILFKEKAILEAKRVIHPQGVFTVKLGDIHISEQALNRVSG
FISVYIIIFAGGWLALLGCGLDIPTAFSTIATTLSNVGPGLGDIGSNFKNLPKEALWICNFAMIAGRLEIFTILVLFMPD
FWRK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=479, Percent_Identity=43.8413361169102, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787626, Length=478, Percent_Identity=35.3556485355649, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53567; Mature: 53567

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCC
>Mature Secondary Structure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HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]