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The map label for this gene is gcp [H]

Identifier: 134301356

GI number: 134301356

Start: 248104

End: 249114

Strand: Direct

Name: gcp [H]

Synonym: FTW_0237

Alternate gene names: 134301356

Gene position: 248104-249114 (Clockwise)

Preceding gene: 134301355

Following gene: 134301357

Centisome position: 13.07

GC content: 35.51

Gene sequence:

>1011_bases
ATGATAGTACTTGGTATTGAGAGCTCCTGTGATGAAACAGGTTTAGCGATATATGATTATTCAAAAAAGAAATTAATTGC
AGATGAATTATATAGCCAAGTCAAATTGCATAAGAAGTATGGTGGTGTTGTACCGGAACTTGCCTCGCGTAAGCATATCG
CTAAGCTTAATCTTTTAGCTAAGAAAATATTCAAAGAAACTGGTCTTAGCTTTGAAGATATTGATTGTATAGCATATACC
GCGATGCCTGGTTTAGTTGGTGCATTGATGGTTGGAGCTACATTTGCCAAAACACTAGGCTTAATCCATAATATTGATAC
AATTGCAGTTCATCACCTTGAGGGTCATCTTTTATCACCATTATTGGATCACAATAGTAATATAGAATATCCTTTCGTAG
CCTTGCTAGTTTCTGGAGGACATACACAACTATTTGAGGTAAAAGAGTTTGGTGAGTATAGTTTACTAGGGGAATCAATT
GATGATGCAGCAGGTGAGGCATTTGATAAGACGACTAAGCTTTTAGGTATGGGTTATCCTGGTGGAGTTGAGGTGGCAAA
TTTAGCTGATCAAGCTACTGATAAGTCTAAGTATATTCTACCAAGGCCGATGAAAAATAAACCTAATTTAGATTTTAGCT
TTAGTGGTTTAAAAACTGCTGTGCTAAATACATGGTATGATGAGCAAGATCAGTCATTAGAGAATAAGGCAAATCTATGC
TACGCATTCCAAGATGCGGCTATAGATGTATTGGTTTCTAAATGTGCTAAAGCATTACAAAAAACTAAAAATACAAGATT
GGTTATTTCAGGCGGAGTCAGTGCAAATAAACTATTGCGTCATCAGCTAGATTTATTGGCTAAAAATAGAGGATATCAAA
TATTTTTTCCTCCAATGAAATATTGTACAGATAATGGTGCAATGATTGCTCTAGCGGGAGCATATAGGTATGTAAATGGT
TTTAAGGACTCTAATTTAGAGATTAATGTTAAAGCAAGATCACCACTCTAG

Upstream 100 bases:

>100_bases
TTGTCTTAATGTCTATAGCTTTTGTTTTAGGCTTATTGCTTGGTTCTTTTATAACTAAGTTTATTCAGATAACTAAAACA
AGTGGTGGCGCTAAAAAGTA

Downstream 100 bases:

>100_bases
CATTTATATCAAAGCACTATCAAAAAAATCATCAATGTGCTATCATTAAGTTGTAATAAATTTCCACATCCACATAAAGT
GGGTCAATTCAAAAAGGGTT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL

Sequences:

>Translated_336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL
>Mature_336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=344, Percent_Identity=32.5581395348837, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI8923380, Length=324, Percent_Identity=29.320987654321, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=55.0595238095238, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=30.3030303030303, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=28.1345565749235, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=360, Percent_Identity=32.5, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322891, Length=354, Percent_Identity=26.5536723163842, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129063, Length=336, Percent_Identity=33.9285714285714, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI21357207, Length=335, Percent_Identity=30.4477611940298, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36859; Mature: 36859

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHH
KKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSP
HHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHH
LLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYP
HHCCCCCCCCCEEEEEEECCCCEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
CCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHCCCEE
YAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMK
EEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCHH
YCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
HHCCCCCEEEEEHHHHHHCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHH
KKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSP
HHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHH
LLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYP
HHCCCCCCCCCEEEEEEECCCCEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
CCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHCCCEE
YAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMK
EEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCHH
YCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
HHCCCCCEEEEEHHHHHHCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA