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The map label for this gene is rpoC

Identifier: 134301354

GI number: 134301354

Start: 243512

End: 247765

Strand: Direct

Name: rpoC

Synonym: FTW_0235

Alternate gene names: 134301354

Gene position: 243512-247765 (Clockwise)

Preceding gene: 134301353

Following gene: 134301355

Centisome position: 12.83

GC content: 36.72

Gene sequence:

>4254_bases
GTGAATAACGGTATCCTACATCAAAATTACAATAGTAAAAAGTTTGATATTATTAAAATATCTTTAGCATCGCCTGAGGT
TATTCGTTCGTGGTCTCATGGTGAAGTTAAAAAACCAGAAACTATAAACTATAGAACATTTAAGCCTGAAAGAGACGGAT
TATTCTGTGCTAAGATATTTGGTCCAATAAAAGACTATGAATGCTTATGTGGTAAGTACAAAAGACTTAAGCACCGTGGC
GTAGTCTGTGAGCGTTGTGGTGTTGAGGTTGAGCAAGCTAAAGTAAGAAGAGAAAGAATGGGGCACATTGATTTAGTATG
TCCTGTAGTACATATTTGGTATCTAAAGTCTTTACCTTCTAGAATTGGTTTATTTTTGGATATGCCATTAAAGAATGTTG
AGAAGGTTTTATACTTTGAGTCATACATAGTTACTGACCCAGGTATGACTCCATTAGAGAAAAAACAACTTCTTACAGAT
GAAGAGTATGCTGAAGCATTAGAAAATTATGGTTATGAGTTTGAAGCATCTATGGGTGCTGAAGCAATAAGAGATTTATT
GGCAGACACTGATATTGAGTCAGAGATTGAGTTACTTCAAGCTGAATGTGAAGAGAGTAAATCTACAGCTAAGAAAGAAA
AAGCTATTAAGAGATTAAGACTTCTTGAAACTTTCCAAGCTTCTGGTAATAAACCTGAATGGATGGTAATGACAGTACTA
CCTGTATTACCACCGGATTTAAGACCATTGGTACCAATCGAAGGTGGTAGATTTGCAACTTCTGATCTTAATGACTTATA
TCGCCGAGTAATCAACAGAAACAATAGACTTAAGAAGCTATTGGACCTAAATGCTCCTGATATTATTGTCAGAAATGAAA
AGAGAATGTTACAAGAAGCGGTAGATGCTTTATTAGATAATGGTAGACGTGGTAGAGCAGTAACGGGCTCTAATAAAAGA
CCACTTAAATCATTAGCAGATATGATTAAGGGTAAACAAGGTCGTTTCCGTCAAAACTTATTAGGTAAGCGTGTTGACTA
TTCTGGTCGTTCTGTAATTACAGTTGGTCCATCTTTGAGATTACATGAGTGTGGTTTACCTAAGAAGATGGCACTAGAGT
TATTTAAACCATTTGTATACTCTAAGCTAAGGTTAGGTGGTCATGCAACGACTATCAAACAGGCTAAGAGAATGGTTGAG
CTTGAGGAAGCTGTAGTATGGGATATTCTTGAAACTGTGATTAATGAGCATCCGGTATTACTAAACCGTGCTCCTACATT
ACATAGACTAGGTATTCAAGCGTTTGAGCCTAGACTTATTGAAGGTAAGGCTATACAGCTACATCCATTAGTTTGTGCTG
CGTTTAACGCTGACTTTGATGGTGACCAAATGGCTGTACACGTACCATTAACAGTTGAGTCGCAACTAGAAGCTAGAGTA
TTGATGATGTCAACAAACAACATCTTATCACCAGCATCTGGTCAACCGATTATTACTCCTACTCAAGATATTGTATTAGG
TCTATACTATATCACTAGAGAGAAAGAAGGTGCGCGTGGCGAGGGTAAATTATTCTCTAGCTATGAGGATGTTAGTAGAG
CTTATAACTCAGGGACTATAGATATCCATGCTAAGATTAAACTAAGAATAGATAGACAAGTATTTGATACTAAAGGTAAT
ACATACAATGAGAAAGGTGTTGTTAATACTACCGTTGGTAGAGCACTTTTATTGAATATACTACCAGAAGGTCTATCTTT
CTCTCTATTAAATAAAGTACTAGTTAAGAAAGAAATTTCTAAAATTATTAATCAGGCATTTAGAGTCTTAGGTGGTAAAG
CTACGGTAGTTTTAGCAGATAAGTTGATGTATGCAGGATTTAAATATTCAACATTGTCAGGGGTATCTGTTGGTGTTGAT
GATATGACTATTCCTGATAACAAAGAAGCTAAAATTGAAGAAGCAGAAAAAGAAATTAAGCAAATTACCGAACAGTATCA
GTCTTCATTAATTACTGAAAATGAGAGATATAACAATATTATCAATATTTGGAGTAAGACTTCAGATGAGGTTGGAGCTT
CGATGATGGATGCTATATCTAAAGATACAGTTAGTATTAACGGTGAGAAAAAAGAAATCGAGTCATTCAACTCTGTATAT
ATGATGGCTAAATCAGGTGCAAGGGGTTCTTATAATCAGATGAGACAGCTTGCAGGTATGCGTGGTCTGATGGCTAAGCC
AGATGGTACGATGATTGAAACTGCAATTACAGCAAACTTTAGAGAAGGTCTGTCAGTATTGCAGTACTTTACATCTACGC
ACGGTGCACGTAAAGGTCTAGCTGATACGGCTCTTAAGACAGCTAACGCGGGTTATCTGACGCGTAGACTAGTTGATGTG
GCTCAAGATTTAGTTGTTATTGAAGAAGATTGTGGTACTGATGATGGTTTGATGTTCTCAGCTATCGTTGAAGATGGTGA
AGTCAAAGTTCCTCTAGTAGAGCGTGCTTTAGGAAGAACTTTAGCAGCAGATGTGGTTACTGAGAAGGGGGTTGTATTGC
TTGAAGCAGGTACTTTATTAGATGAGAATCTTGTTGAGTTACTTGATGATAACGGTATTGATATGATCAAAGTCAGATCA
CCAATAACTTGTAAAACACGTAGAGGATTATGTGCTAAGTGTTATGGTCGTGATCTAGCGCGTGAAAGACAAGTTAATGT
TGGGGAATCTGTAGGTGTGATTGCTGCTCAATCAATTGGTGAGCCAGGTACGCAGTTGACAATGAGAACATTCCACACTG
GTGGTGCTGCGTCTCTGGGTATTACAGTTTCTGACATTAAAGTTAAAACTGCTGGTAAGATTAAGTTTAAGAATATTAGA
ACTGTAACTAACAAAGAAGGTCAAGAAATTGTTATATCTCGCGCAGGTGAGATTATCGTTTCTGATACTATGGGTAGAGT
GAGAGAACAGCATAAGATCCCTATGGGTGCAGTCGTTCCTTTAGCTAGTGGTAAAGCAGTAGAAATTGGTGATGTGATTG
CTACGTGGGATCCGCATGCTCAGCCATTAATTACAGATGTTGCTGGTAAAGTTGTTCTTGAAGATGTGATTGATGGTATA
ACATCTAAGCATACTTATGATGATTTGACTGGTCAGCAAACTATTGAGATAACTTCAATATCTCAAAGAACAACATCTAA
AAACTTAAAACCAGTTGTTAAGATTGTTGATGAAAAGGGTGCCGAGCTTAAGTCAATACCTCTAGCAGTTGGAGCAGTAC
TAAACGTTGCCGATGATTCTATACTAGAAGTTGGTGATATCGTAGCTAAGATTCCTCTAGAAGGTTCTAAGAACAAAGAT
ATTACCGGGGGTCTTCCACGTGTTGCTGAGCTTTTCGAAGCTAGACGTCCTAAAGATGCGGCAATACTTTCTCCATGTGA
TGGTATGGTTAGGCTTGGTAACAGAGACACTAAAGAAAAACAGCGTATTGAGATTATAGATAAAAATGGTCATATTGTTG
AAGAGATATTATTACCTAAGTCTCGTCACCTAGTAGTTTTTGATGGTGAGCAGGTTTCTAGGGGTGATGTTTTAGCTGAT
GGACCTACTGATCCACATGATCTTCTTAAGTACAAAGGACTTGAGGAATTTGCTGATTATATTCTTATCGAAGCGCAGTC
TGTATATCGTATGCAGGGTGTTGTTATTAATGATAAGCATATTGAAACAATTGTAAGACAAATGTTAAGAAAAGCTGTAA
TCCTTGATGAAGGTGATAGTAAGTTTGTCAAAGATGAAAGTATTGAGTTAGTAAGAATACTTGAAGAAAATGATAAACTA
CGTAAGCAAGGTAAAAAAGAAGTAGAGTATGAGCTGGTATTAATGGGTATTACACGTTCTTCTTTATCTACGGAGTCATT
CTTATCGGCTGCTTCTTTCCAAGAAACAACAAGAGTGCTTACTGAGGCTTCGATAAACTCACAAATTGATAATTTAAGAG
GACTTAAAGAAAATGTTCTTATTGGTAGATTAATACCAACAGGTACTGGTCTAGCAGTAAGAAAAGAGTCAGCTAAAATT
GAAAAAATGCGTGAAGAATTAGGGGTTGAAGATAATATGGTGTTTACTGATTTATCGTCTTTTAACCCTGAAGAAATCTC
TTTTGATAGTATTCAATCTCAAAAAGAAGATAAAGATATTAATGAAGACATCGAGGAGTCATTAAGAAACGCTCTTGAGT
CACTTGATTTCTAA

Upstream 100 bases:

>100_bases
ATAGATATGGATTTTGACTATTCATCTGAGGAAGAATAAGCATCTTAATTTAAAGCTACTTATTTTTTGTTATTAAAATA
AAAGTATAGGAGAATTACCA

Downstream 100 bases:

>100_bases
TCTTTATTCATTTTCTCAATTTTTCAATCTAAATAAAATTTTATTATTCAAATATTTTAAATTATAATAAAGAGCATATT
CTAGTATTAATAATTATGGT

Product: DNA-directed RNA polymerase, beta prime subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1417; Mature: 1417

Protein sequence:

>1417_residues
MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRG
VVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPSRIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTD
EEYAEALENYGYEFEASMGAEAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVL
PVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEAVDALLDNGRRGRAVTGSNKR
PLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLRLHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVE
LEEAVVWDILETVINEHPVLLNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARV
LMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTIDIHAKIKLRIDRQVFDTKGN
TYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEISKIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVD
DMTIPDNKEAKIEEAEKEIKQITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVY
MMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGLADTALKTANAGYLTRRLVDV
AQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRTLAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRS
PITCKTRRGLCAKCYGRDLARERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIR
TVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHAQPLITDVAGKVVLEDVIDGI
TSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKGAELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKD
ITGGLPRVAELFEARRPKDAAILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLAD
GPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDSKFVKDESIELVRILEENDKL
RKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVLTEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKI
EKMREELGVEDNMVFTDLSSFNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF

Sequences:

>Translated_1417_residues
MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRG
VVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPSRIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTD
EEYAEALENYGYEFEASMGAEAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVL
PVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEAVDALLDNGRRGRAVTGSNKR
PLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLRLHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVE
LEEAVVWDILETVINEHPVLLNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARV
LMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTIDIHAKIKLRIDRQVFDTKGN
TYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEISKIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVD
DMTIPDNKEAKIEEAEKEIKQITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVY
MMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGLADTALKTANAGYLTRRLVDV
AQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRTLAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRS
PITCKTRRGLCAKCYGRDLARERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIR
TVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHAQPLITDVAGKVVLEDVIDGI
TSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKGAELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKD
ITGGLPRVAELFEARRPKDAAILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLAD
GPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDSKFVKDESIELVRILEENDKL
RKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVLTEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKI
EKMREELGVEDNMVFTDLSSFNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF
>Mature_1417_residues
MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRG
VVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPSRIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTD
EEYAEALENYGYEFEASMGAEAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVL
PVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEAVDALLDNGRRGRAVTGSNKR
PLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLRLHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVE
LEEAVVWDILETVINEHPVLLNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARV
LMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTIDIHAKIKLRIDRQVFDTKGN
TYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEISKIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVD
DMTIPDNKEAKIEEAEKEIKQITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVY
MMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGLADTALKTANAGYLTRRLVDV
AQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRTLAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRS
PITCKTRRGLCAKCYGRDLARERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIR
TVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHAQPLITDVAGKVVLEDVIDGI
TSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKGAELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKD
ITGGLPRVAELFEARRPKDAAILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLAD
GPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDSKFVKDESIELVRILEENDKL
RKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVLTEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKI
EKMREELGVEDNMVFTDLSSFNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=1041, Percent_Identity=24.4956772334294, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI4505939, Length=663, Percent_Identity=25.4901960784314, Blast_Score=181, Evalue=6e-45,
Organism=Homo sapiens, GI103471997, Length=603, Percent_Identity=25.3731343283582, Blast_Score=125, Evalue=4e-28,
Organism=Escherichia coli, GI2367335, Length=1363, Percent_Identity=62.0689655172414, Blast_Score=1736, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=679, Percent_Identity=26.5095729013255, Blast_Score=196, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI71987878, Length=303, Percent_Identity=29.7029702970297, Blast_Score=149, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320061, Length=989, Percent_Identity=23.7613751263903, Blast_Score=192, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6324690, Length=678, Percent_Identity=26.1061946902655, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324917, Length=800, Percent_Identity=25, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281360912, Length=1046, Percent_Identity=24.1873804971319, Blast_Score=194, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17530899, Length=317, Percent_Identity=30.2839116719243, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17647875, Length=761, Percent_Identity=24.0473061760841, Blast_Score=137, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_FRAT1 (Q14JT4)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666342.1
- ProteinModelPortal:   Q14JT4
- SMR:   Q14JT4
- STRING:   Q14JT4
- GeneID:   4200329
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0145
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q14JT4
- ProtClustDB:   PRK00566
- BioCyc:   FTUL393115:FTF0145-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 157419; Mature: 157419

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIF
CCCCCEECCCCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEHHH
GPIKDYECLCGKYKRLKHRGVVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPS
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTDEEYAEALENYGYEFEASMGA
HHCEEEECCHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCEEECCCCH
EAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
PVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEA
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECHHHHHHHH
VDALLDNGRRGRAVTGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLR
HHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCE
LHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVELEEAVVWDILETVINEHPVL
ECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARV
EECCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCEEEEEEEEEECCCCCEEE
LMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTI
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHCCCCEE
DIHAKIKLRIDRQVFDTKGNTYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEIS
EEEEEEEEEECCHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVDDMTIPDNKEAKIEEAEKEIK
HHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHH
QITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVY
HHHHHHHHHHCCCCHHHCCHHHHHCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHEE
MMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGL
EEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHCCH
ADTALKTANAGYLTRRLVDVAQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRT
HHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCEECHHHHHHHHHH
LAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRSPITCKTRRGLCAKCYGRDLA
HHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
RERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIR
HHHCCCCCCCCCCEEHHCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCEEEECEE
TVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHA
ECCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCEEEECCEEECCCCCC
QPLITDVAGKVVLEDVIDGITSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHCCCCCHHHHHHHHCCC
AELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKDITGGLPRVAELFEARRPKDA
CCHHHCHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
AILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLAD
EEECCCCCHHCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEC
GPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDS
CCCCHHHHHHHCCHHHHHHHEEHHHHHHHHEECEEECHHHHHHHHHHHHHHHHEECCCCC
KFVKDESIELVRILEENDKLRKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVL
CCCCCCCHHHHHHHHCCHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKIEKMREELGVEDNMVFTDLSS
HHHHHHHHHHHHCCCHHCCEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCC
FNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIF
CCCCCEECCCCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEHHH
GPIKDYECLCGKYKRLKHRGVVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPS
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTDEEYAEALENYGYEFEASMGA
HHCEEEECCHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCEEECCCCH
EAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
PVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEA
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECHHHHHHHH
VDALLDNGRRGRAVTGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLR
HHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCE
LHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVELEEAVVWDILETVINEHPVL
ECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARV
EECCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCEEEEEEEEEECCCCCEEE
LMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTI
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHCCCCEE
DIHAKIKLRIDRQVFDTKGNTYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEIS
EEEEEEEEEECCHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVDDMTIPDNKEAKIEEAEKEIK
HHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHH
QITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVY
HHHHHHHHHHCCCCHHHCCHHHHHCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHEE
MMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGL
EEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHCCH
ADTALKTANAGYLTRRLVDVAQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRT
HHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCEECHHHHHHHHHH
LAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRSPITCKTRRGLCAKCYGRDLA
HHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
RERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIR
HHHCCCCCCCCCCEEHHCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCEEEECEE
TVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHA
ECCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCEEEECCEEECCCCCC
QPLITDVAGKVVLEDVIDGITSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHCCCCCHHHHHHHHCCC
AELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKDITGGLPRVAELFEARRPKDA
CCHHHCHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
AILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLAD
EEECCCCCHHCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEC
GPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDS
CCCCHHHHHHHCCHHHHHHHEEHHHHHHHHEECEEECHHHHHHHHHHHHHHHHEECCCCC
KFVKDESIELVRILEENDKLRKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVL
CCCCCCCHHHHHHHHCCHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKIEKMREELGVEDNMVFTDLSS
HHHHHHHHHHHHCCCHHCCEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCC
FNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA