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The map label for this gene is atpA [H]

Identifier: 134301276

GI number: 134301276

Start: 147238

End: 148779

Strand: Direct

Name: atpA [H]

Synonym: FTW_0138

Alternate gene names: 134301276

Gene position: 147238-148779 (Clockwise)

Preceding gene: 134301275

Following gene: 134301277

Centisome position: 7.76

GC content: 38.46

Gene sequence:

>1542_bases
ATGCAATTAAGTCCATCAGAAATAAGTGGTTTAATAAAACAAAGAATCGAGAAGTTTGACAATTCAGTTGAACTAAAATC
AGAAGGTACAATCGTCAGTGTTGCTGATGGTATCGTTACTATTTATGGATTAAATGATGTTGCTGCTGGTGAAATGATTA
AATTACCAGGCGATGTTTATGGTCTAGCTCTGAACTTAAATACAGATTCGGTTGGTGCTGTAGTTTTAGGGGATTATGAG
CATATTAAAGAAGGCGATAAAGCATACTGTATTGGTAGAATACTAGAAGTCCCAGTTGGAGAGGCTCTCTTAGGCAGAGT
TGTTGATGCTTTAGGTAATCCTATCGATGGTAAGGGTGAAGTGGCAACTGATTTAACTTCACCTATCGAAAAAATTGCTC
CAGGTGTTATTTGGAGAAAATCAGTAGATCAAGCGCTACAAACAGGTATTAAGTCAATTGACTCAATGGTACCAATTGGT
AGAGGTCAAAGAGAGCTTATCATTGGAGATAGACAGATAGGTAAAACCGCAATTGCTGTTGATACGATTATTAACCAAAA
GGGTACAGGTGTTAAGTGTATCTATGTTGCTATTGGTCAGAAGGCATCTACAATTGCAAACATTGTAAGACAGCTTGAAG
AGCATGGCGCAATGGAACATACAATTATTGTTGCAGCTACAGCATCTGATTCTGCAGCGCTGCAATATATCGCGCCTTAT
GCGGGATGTTCTATGGGTGAATACTTTAGGGATCGCGGTCAAGATGCACTTATTGTTTATGATGATTTGACTAAACAAGC
ATGGGCTTATAGACAGATTTCACTTTTATTAAGAAGACCGCCTGGACGTGAAGCTTATCCTGGTGATGTATTCTATCTTC
ACTCTAGACTTCTTGAAAGAGCTGCAAGAGTCAACGAAGAATATGTCGAGAAATTTACAAATGGTGAAGTGAAAGGTAAG
ACAGGTTCTTTGACTGCACTACCTATCATTGAAACACAAGCTGGTGATATCTCTGCATTCGTTCCAACGAACGTTATATC
AATCACTGACGGGCAGATATTCTTAGAGACAGATTTATTTAACTCTGGCTTAAGACCTGCGATAAACCCTGGTAACTCTG
TTTCACGTGTCGGTGGTGCAGCACAAACTAAGATTATCAAGAAACTTGGTGGTGGTATCCGTTTGGCACTTGCGCAATAT
AGGGAGCTAGAGGCGTTCTCACAATTTGCATCAGACTTGGATGAAGCAACTCGTGCACAATTAAACAGAGGTCAAAGAGT
AACAGAATTGCTAAAACAAAAGCAATTCTCAACTTTATCTGTGGCTTTAATGGCATTGTCACTTTATGCTGCTGATAATG
GATACTTAGATAACTTAGAGGTTTCAGAGGTTATACCTTTTGAATCTGCGCTACATGCATTAGCAGAAACAAAGTATAGT
GATGTAATTGCAGAAATTAATGAAACTGGTAAGTATGATGCTGATATTGCTGATAAGTTAAAAATTATTGTTGAAGACTG
TAAAGCAAATCAAGCTTGGTAA

Upstream 100 bases:

>100_bases
AGTAGTCAAGGTTGGGGATACAGTTATTGATAGTTCAGTATCTGGCCATTTAGAGAAATTAAAAAGTATTTTGTTATCAT
AAATTATAGGAAGTGAGCTT

Downstream 100 bases:

>100_bases
TAGGAGTATAGACTATGTCTAACGCTAGAGAAATACGTTCCAAAGTACAGAGTGTTAAAAACACGCAAAAAATCACAGGT
GCAATGGAATTAGTTGCTGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCIGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETGKYDADIADKLKIIVEDCKANQAW

Sequences:

>Translated_513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCIGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETGKYDADIADKLKIIVEDCKANQAW
>Mature_513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCIGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETGKYDADIADKLKIIVEDCKANQAW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=512, Percent_Identity=56.640625, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI4757810, Length=512, Percent_Identity=56.640625, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI19913428, Length=316, Percent_Identity=28.7974683544304, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI32189394, Length=390, Percent_Identity=23.5897435897436, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI19913426, Length=312, Percent_Identity=27.5641025641026, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI19913424, Length=256, Percent_Identity=26.953125, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=70.9551656920078, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=377, Percent_Identity=24.1379310344828, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788251, Length=382, Percent_Identity=26.7015706806283, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=509, Percent_Identity=55.4027504911591, Blast_Score=556, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988080, Length=509, Percent_Identity=55.4027504911591, Blast_Score=556, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=509, Percent_Identity=51.6699410609037, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17570191, Length=310, Percent_Identity=29.0322580645161, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=309, Percent_Identity=27.1844660194175, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=384, Percent_Identity=22.9166666666667, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=256, Percent_Identity=26.5625, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=514, Percent_Identity=52.7237354085603, Blast_Score=547, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6319603, Length=309, Percent_Identity=30.0970873786408, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=385, Percent_Identity=24.1558441558442, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=55.2268244575937, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=312, Percent_Identity=27.5641025641026, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646341, Length=312, Percent_Identity=27.5641025641026, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136796, Length=312, Percent_Identity=27.5641025641026, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24638766, Length=392, Percent_Identity=23.9795918367347, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.8566978193146, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24583988, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583992, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=27.2, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55435; Mature: 55435

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVY
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCEEECCCCEE
GLALNLNTDSVGAVVLGDYEHIKEGDKAYCIGRILEVPVGEALLGRVVDALGNPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
VATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHH
DTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHH
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQ
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DVIAEINETGKYDADIADKLKIIVEDCKANQAW
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVAAGEMIKLPGDVY
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCEEECCCCEE
GLALNLNTDSVGAVVLGDYEHIKEGDKAYCIGRILEVPVGEALLGRVVDALGNPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
VATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHH
DTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHH
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQ
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DVIAEINETGKYDADIADKLKIIVEDCKANQAW
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA