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The map label for this gene is nuoN [H]

Identifier: 134301259

GI number: 134301259

Start: 129088

End: 130539

Strand: Direct

Name: nuoN [H]

Synonym: FTW_0119

Alternate gene names: 134301259

Gene position: 129088-130539 (Clockwise)

Preceding gene: 134301258

Following gene: 134301260

Centisome position: 6.8

GC content: 35.47

Gene sequence:

>1452_bases
ATGAGTTTATCAATCCTTTATATTTTGCCAGAAATACTACTAGCACTAGGTGTCATAGTTGTAATGTTTTCTGGACTTTT
TCTACATGGTAAGATTAGAAACATTAACTATATTTTTTTCCAAGTATTTACACTACTTGCTTTGATAGCAACTTTTGCTA
AAGAGTATCTGATACAGACTACTGGCTCAGTGTTTGAGGGTCAGGTTGTATTTAGTGGCTTTGCATATACATTACAACTA
GTAATACTTGTCTTAGCAGTCTTTGTTGCATTATATTCAAGAGATTATGTCAAAGATAGAAAAATATCAGATGGTGATTT
CTATACATTGTTAATGCTATGCGTACTTGGTGCAATGGTTTTAACAGCGGCACATAGTTTAGTTACAATATATGTTGGTC
TAGAGTTATTATCATTACCAATGTATGCATTGATCGCAATCTATAGAGATTCAGGCAAAGGTCTTGAGGCCGCGATCAAA
TACTTTGTTTTAGGGGCTATTGCATCGGCTCTACTATTATTTGGGATGTCATTTGTCTATGGAATGACAGGCAAGCTTGA
TATTACAGAAATAGCCAATGTATTAGCACATGGTAACTTCGCAGGCTTACAGCAGCAGTTTTTGCTTGTATGCTTGGTAA
TGATGATCGCTACATTTTTATTCAAACTTGGTGCTTTCCCTTTTCATATGTGGTTACCAGATGTTTATCAAGGTGCTCCA
AACGCAGTAGCAAATATCGTTGCAACTATTCCAAAAGTTGCTGCCTTTGCGATGCTTGTGAATATCTTATTTGTTGGCTT
CCCATCACTAAAAGATTCATGGATATATCTGTTTAGGATTATAGGTATATTGTCAATATTTTTTGGTAGCTTGGTGGCAC
TCTCACAGACTAATGTTAAACGACTTTTGGGTTACTCAACAGTTTCACAGATTGGTTTTGTGCTATTGGCAACAACATTA
AATCCTCAAGGATATGCCTTAACTGCGGCAAGCTTCTATGTCATAGTGTATGTATTTACAACTTTAGCTGTATTTGGCGT
ACTTACAACTATTTCTGTCGGGGGATATGAAGTTCAGGATCTTAATGACTTAAAAGGTTTCAACACAAAAGATTCATGGT
TAGCATTTATCTTGTTGATTGTGCTATTTTCAATGGCGGGTATCCCTCCATTTGGTGGCTTTATTGCTAAACTATTTGTA
GTTATGGGATTAATTAATGATGGTAATTACTTCTTGGCGTGTTTTGTACTATTTATGGCAGTAATAGCATCATTCTACTA
TGTGCGTGTCATCAAAACCATGTACTTTGATGATCCTGATAATGATGAAACTGTTAAGCCACCGTTGACATCTCTAATAG
CATTAAGTATTAACGGTTTGGTACTATTATTCTTAGGGATTATGCCAATGCTCCTTTTGGGAGTTCTTACCCAAGTTACT
AATGTTATATAA

Upstream 100 bases:

>100_bases
GACTTTATTGTTTGGTTTCTATCCAGAGCCAATTTTGCAGCTATCAGCAGCAGCATCGGCACATATTGTTGGTCTATCTC
TATAAGGTGGTGTTTTGATT

Downstream 100 bases:

>100_bases
AAACTAATAGTTTATTGCCTATTGTCATTATTACTTTTATACTTTTATCTAGAAACAATTAAATTTTATTAGCTGATGAA
GGAAATTCTAGGACCGCTTA

Product: NADH dehydrogenase I, subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGSVFEGQVVFSGFAYTLQL
VILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIK
YFVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVCLVMMIATFLFKLGAFPFHMWLPDVYQGAP
NAVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTL
NPQGYALTAASFYVIVYVFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFV
VMGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVT
NVI

Sequences:

>Translated_483_residues
MSLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGSVFEGQVVFSGFAYTLQL
VILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIK
YFVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVCLVMMIATFLFKLGAFPFHMWLPDVYQGAP
NAVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTL
NPQGYALTAASFYVIVYVFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFV
VMGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVT
NVI
>Mature_482_residues
SLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGSVFEGQVVFSGFAYTLQLV
ILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIKY
FVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVCLVMMIATFLFKLGAFPFHMWLPDVYQGAPN
AVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTLN
PQGYALTAASFYVIVYVFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFVV
MGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVTN
VI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=303, Percent_Identity=27.3927392739274, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI145693160, Length=480, Percent_Identity=30.2083333333333, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1788614, Length=425, Percent_Identity=25.1764705882353, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788613, Length=317, Percent_Identity=26.813880126183, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788827, Length=330, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788831, Length=320, Percent_Identity=25.3125, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52982; Mature: 52851

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCC
>Mature Secondary Structure 
SLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQT
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH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HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA