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The map label for this gene is figB [C]

Identifier: 134301243

GI number: 134301243

Start: 111980

End: 113242

Strand: Reverse

Name: figB [C]

Synonym: FTW_0103

Alternate gene names: 134301243

Gene position: 113242-111980 (Counterclockwise)

Preceding gene: 134301244

Following gene: 134301242

Centisome position: 5.96

GC content: 31.04

Gene sequence:

>1263_bases
ATGAATAATCATATAAAAGCACAAATACTGTTACTATGCTTTTGTCAGCTTATAATCATAGCAGCTATGGAAATGAGTAA
TCCTTTTTTACCAATTTACTTACAATCCCTCGGCGATTTTGATCTACTACCAGTAAATGCCTGGAATGTCTTAGCTTATG
CAATGCCTTTAATATCAGCAATGCTTTTCTCTCCTTTTTGGGGTAAATATGCCGATAGATTTGGCTATAAAACAATGATC
CTTAGAGCTGCCTTAGCTTTAGCTATTATACAATTGCTGATATATCTAACAAATAGTGCTTTGCTATTTATAACCCTAAG
ATTTATCCAAGGAGCTATAGCTGGATTTTTATTAGCAGCTCAAAGCTATGCTGTAGTTATTGTTTCAAAAGAATTTAGAA
GTCGTATACTTGCCTGGTTACAATCATCTACGGCAATCGGTATCGCTATAGGTCCTTTGATAGGTGGTGTTTTAGCCACA
TTACTTAGTTATAACCAAATATTTTTGATTTGTGCTGTTATAGCTTGCTGTATCTTTATCATCTTACTGATTAAATTAGA
AAGTATCTCAAACCCTTCTTTATTATCAAAACAAGATAATAATAAAAATTGCTATCATAAAAATACTTCTAATAACTATT
TAATATATGTTTATTTCTCGGTAATTTTCTTAGCTATTTTATTATCTCAAACGGCAAAATTTTTGCCACAATCATTTTTT
GCCATTTATGCTAAAGAGTTTTTTAGCTCAGACCCGATAATCATAGCAGCCATTTATGCAGCACCTGCATTTAGTCTACT
GCTATTTTCAGCGCCGATAGGTTATTTATTTGATAAGCTCCTTAACAAACAAGTTAATAATCAATATTTCTTTGCCAGTA
GCTATTTTATAATTTTGTTTGCAATATCCACTGTAGCAATTTATGTTCATGGATTTACACACAACATTTATCTTATATTA
GCAGCTAGATTCATACTTGGAGTTACCTTTGCCGGCACACTACCATGCTTATTTAGCTTAGCATGTAGAACTAAAGATAA
TAATTTTGGTTTTCTAATTGGCTACTGTAATACGTTCTCTAAATTTGGAAATCTCTGTGGCATTTTCCTGGGTGGATTTA
TATTCCAAATATCAAGCATGCAAACAGTTTTCTATGTTACTGCTATTATCTATATGTTTTTAGTAGTTATCTACATATGT
CTACTTTATCTATTTGACCTTAAATCATCTAATTTTAAAAATAAGGAATTAATAAATGTCTAA

Upstream 100 bases:

>100_bases
ACTTACTAGAATGCGTTTAAATGACAAACTAGAGTGCGATAAAGATGACATGCAAGGAGATATCTATATCAACCTCAAAA
ATCCATTAGCTTAAAAAATC

Downstream 100 bases:

>100_bases
ACTAAGCGATTCAAAGAGTGTTTTTAGTAAACTTTCAAACAAACAAATTGAAACAATTATTCAAAGATATGCTTCGCCAT
GCTTTATCATCGATGAAAAT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPVNAWNVLAYAMPLISAMLFSPFWGKYADRFGYKTMI
LRAALALAIIQLLIYLTNSALLFITLRFIQGAIAGFLLAAQSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLAT
LLSYNQIFLICAVIACCIFIILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVIFLAILLSQTAKFLPQSFF
AIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLLNKQVNNQYFFASSYFIILFAISTVAIYVHGFTHNIYLIL
AARFILGVTFAGTLPCLFSLACRTKDNNFGFLIGYCNTFSKFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYIC
LLYLFDLKSSNFKNKELINV

Sequences:

>Translated_420_residues
MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPVNAWNVLAYAMPLISAMLFSPFWGKYADRFGYKTMI
LRAALALAIIQLLIYLTNSALLFITLRFIQGAIAGFLLAAQSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLAT
LLSYNQIFLICAVIACCIFIILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVIFLAILLSQTAKFLPQSFF
AIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLLNKQVNNQYFFASSYFIILFAISTVAIYVHGFTHNIYLIL
AARFILGVTFAGTLPCLFSLACRTKDNNFGFLIGYCNTFSKFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYIC
LLYLFDLKSSNFKNKELINV
>Mature_420_residues
MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPVNAWNVLAYAMPLISAMLFSPFWGKYADRFGYKTMI
LRAALALAIIQLLIYLTNSALLFITLRFIQGAIAGFLLAAQSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLAT
LLSYNQIFLICAVIACCIFIILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVIFLAILLSQTAKFLPQSFF
AIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLLNKQVNNQYFFASSYFIILFAISTVAIYVHGFTHNIYLIL
AARFILGVTFAGTLPCLFSLACRTKDNNFGFLIGYCNTFSKFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYIC
LLYLFDLKSSNFKNKELINV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=381, Percent_Identity=25.4593175853018, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47046; Mature: 47046

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPVNAWNVLAYAMPLISA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHH
MLFSPFWGKYADRFGYKTMILRAALALAIIQLLIYLTNSALLFITLRFIQGAIAGFLLAA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLATLLSYNQIFLICAVIACCIFI
CCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVIFLAILLSQTAKFLPQSFF
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLLNKQVNNQYFFASSYFIILF
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHHHH
AISTVAIYVHGFTHNIYLILAARFILGVTFAGTLPCLFSLACRTKDNNFGFLIGYCNTFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
KFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYICLLYLFDLKSSNFKNKELINV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPVNAWNVLAYAMPLISA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHH
MLFSPFWGKYADRFGYKTMILRAALALAIIQLLIYLTNSALLFITLRFIQGAIAGFLLAA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLATLLSYNQIFLICAVIACCIFI
CCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVIFLAILLSQTAKFLPQSFF
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLLNKQVNNQYFFASSYFIILF
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHHHH
AISTVAIYVHGFTHNIYLILAARFILGVTFAGTLPCLFSLACRTKDNNFGFLIGYCNTFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
KFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYICLLYLFDLKSSNFKNKELINV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]