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The map label for this gene is ftsK [H]

Identifier: 134300422

GI number: 134300422

Start: 2810752

End: 2811990

Strand: Reverse

Name: ftsK [H]

Synonym: Dred_2583

Alternate gene names: 134300422

Gene position: 2811990-2810752 (Counterclockwise)

Preceding gene: 134300423

Following gene: 134300421

Centisome position: 77.94

GC content: 45.12

Gene sequence:

>1239_bases
ATGAAGTTTAAAGAGAGCTTACGAGAGGCCAAACGGAAATTTATTTGGAATCTTGGGTACCACCCATTAGTAACACCAAA
GCCAGAGACTTTTATCCAAACCTTAAAGAAGGAGATCCGCACTAGGCCAGGGCGGGAACTAGAGTCCGAAATAGAGAACA
TCATGTTTGAACTTAAGCTTTACAATGGTAGCGGGGAATACGCCATGCACTTGAACACCGTTAAGAAGGCAGAAAATCAC
TTTGTTACCTTCTGGCAGCTCCCCAGAGGGCTCACGTATCGGCAGTATCAGGATAAAAGAGAGGTGTTTTGTAACAACCT
AAAGGCCCAGGTCATTATTGAAGAACGGAACGGTAGTCTGATGATCGAAGTTATCCAGGGGGTTCTACCCAGTAAGAAGG
GCTTTGAATTTGATATAAGTAAATACCCCGACATGCTCTTGCCTGTTATGATTGGCTGGGATCAGGCAGGTCCGGTGGTG
ATAGACTTGCAGAAACTTCCACATTTACTCATAACCGGCACCACTGGCACCGGGAAAAGTATCTGCATGCAAAACATTAT
CTTATCGTTAGCCAATAACTCAAACGTCATGCTATACGGTTGTGATATTGGAAGGGTTAACATGGCCTTTATTAGTGACC
GGGCGGTATTTGCAAAAGACATTTTTGAGTCACTAGATGTCATTAGTTACCTAGTTGGCATTATGAATAAGCGGCTACAG
GTCATCGAGAGTATACCTGGTTGTGTCGATATAGTAGGCTTCAACGAGTCTAATCCTGACAATAAACTGCCTTTCTTGAC
CCTGCTTATTGATGAGTTTGGCTTTACTTCGGAGAAGATGACACGCATCAAGGAAGAAAAGGAGCTCAGGAGGCAGATAT
ATACCAATATAGCTGGTATGGCCTTGCTGGCCAGAAAGACCGGTATCCACCTGGTAGTTGGTTTGCAGAAGTCATCTGAC
GAGCTGATACCAACTACCGTCAGGGATATGTTTACAGGCAGAATAGCCCACCGTGCAGAGTCTCAAAGTGCCAGCCAGGT
TGCTTTAGGCAATTCTGATGCCTATTACCTTCCAAGCACCCCGGGTCGGGCCATTCTTAAAATAGGCAATGAGTTTAGAA
TATTCCAGGGAGCCTTCTACGACCCCAAAAAAGCCCGGGCATATCTGGCCAAAACATCACTAAGGAGGGATAATAGATAT
TATGCTGAACAGCAGACAAATCGGCTTCCAACGAGCTAG

Upstream 100 bases:

>100_bases
TTATATTAAGTATGTTGCCATGATGCTTGGTGTTATCGTTGTTCTTCGGGTTGTCCTGGACCTTTTCCGTGAGGTCGGCA
AGGTAATGGGGGTGTAATAT

Downstream 100 bases:

>100_bases
GGAGATCCGGGACAGCGTGGATCAGTTTGGGGCCTTGGTGATTGAACAACTATATGCAATGCACTTCAAAGGGCTTGCAT
CTGGCATAGATAAGGCTAGG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKFKESLREAKRKFIWNLGYHPLVTPKPETFIQTLKKEIRTRPGRELESEIENIMFELKLYNGSGEYAMHLNTVKKAENH
FVTFWQLPRGLTYRQYQDKREVFCNNLKAQVIIEERNGSLMIEVIQGVLPSKKGFEFDISKYPDMLLPVMIGWDQAGPVV
IDLQKLPHLLITGTTGTGKSICMQNIILSLANNSNVMLYGCDIGRVNMAFISDRAVFAKDIFESLDVISYLVGIMNKRLQ
VIESIPGCVDIVGFNESNPDNKLPFLTLLIDEFGFTSEKMTRIKEEKELRRQIYTNIAGMALLARKTGIHLVVGLQKSSD
ELIPTTVRDMFTGRIAHRAESQSASQVALGNSDAYYLPSTPGRAILKIGNEFRIFQGAFYDPKKARAYLAKTSLRRDNRY
YAEQQTNRLPTS

Sequences:

>Translated_412_residues
MKFKESLREAKRKFIWNLGYHPLVTPKPETFIQTLKKEIRTRPGRELESEIENIMFELKLYNGSGEYAMHLNTVKKAENH
FVTFWQLPRGLTYRQYQDKREVFCNNLKAQVIIEERNGSLMIEVIQGVLPSKKGFEFDISKYPDMLLPVMIGWDQAGPVV
IDLQKLPHLLITGTTGTGKSICMQNIILSLANNSNVMLYGCDIGRVNMAFISDRAVFAKDIFESLDVISYLVGIMNKRLQ
VIESIPGCVDIVGFNESNPDNKLPFLTLLIDEFGFTSEKMTRIKEEKELRRQIYTNIAGMALLARKTGIHLVVGLQKSSD
ELIPTTVRDMFTGRIAHRAESQSASQVALGNSDAYYLPSTPGRAILKIGNEFRIFQGAFYDPKKARAYLAKTSLRRDNRY
YAEQQTNRLPTS
>Mature_412_residues
MKFKESLREAKRKFIWNLGYHPLVTPKPETFIQTLKKEIRTRPGRELESEIENIMFELKLYNGSGEYAMHLNTVKKAENH
FVTFWQLPRGLTYRQYQDKREVFCNNLKAQVIIEERNGSLMIEVIQGVLPSKKGFEFDISKYPDMLLPVMIGWDQAGPVV
IDLQKLPHLLITGTTGTGKSICMQNIILSLANNSNVMLYGCDIGRVNMAFISDRAVFAKDIFESLDVISYLVGIMNKRLQ
VIESIPGCVDIVGFNESNPDNKLPFLTLLIDEFGFTSEKMTRIKEEKELRRQIYTNIAGMALLARKTGIHLVVGLQKSSD
ELIPTTVRDMFTGRIAHRAESQSASQVALGNSDAYYLPSTPGRAILKIGNEFRIFQGAFYDPKKARAYLAKTSLRRDNRY
YAEQQTNRLPTS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=292, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 46954; Mature: 46954

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKESLREAKRKFIWNLGYHPLVTPKPETFIQTLKKEIRTRPGRELESEIENIMFELKL
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEE
YNGSGEYAMHLNTVKKAENHFVTFWQLPRGLTYRQYQDKREVFCNNLKAQVIIEERNGSL
ECCCCCEEEEEHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCE
MIEVIQGVLPSKKGFEFDISKYPDMLLPVMIGWDQAGPVVIDLQKLPHLLITGTTGTGKS
EHHHHHHHCCCCCCCEEEHHCCCCHHHHHEECCCCCCCEEEEHHHCCEEEEECCCCCCHH
ICMQNIILSLANNSNVMLYGCDIGRVNMAFISDRAVFAKDIFESLDVISYLVGIMNKRLQ
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIESIPGCVDIVGFNESNPDNKLPFLTLLIDEFGFTSEKMTRIKEEKELRRQIYTNIAGM
HHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALLARKTGIHLVVGLQKSSDELIPTTVRDMFTGRIAHRAESQSASQVALGNSDAYYLPST
HHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCC
PGRAILKIGNEFRIFQGAFYDPKKARAYLAKTSLRRDNRYYAEQQTNRLPTS
CCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKFKESLREAKRKFIWNLGYHPLVTPKPETFIQTLKKEIRTRPGRELESEIENIMFELKL
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEE
YNGSGEYAMHLNTVKKAENHFVTFWQLPRGLTYRQYQDKREVFCNNLKAQVIIEERNGSL
ECCCCCEEEEEHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCE
MIEVIQGVLPSKKGFEFDISKYPDMLLPVMIGWDQAGPVVIDLQKLPHLLITGTTGTGKS
EHHHHHHHCCCCCCCEEEHHCCCCHHHHHEECCCCCCCEEEEHHHCCEEEEECCCCCCHH
ICMQNIILSLANNSNVMLYGCDIGRVNMAFISDRAVFAKDIFESLDVISYLVGIMNKRLQ
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIESIPGCVDIVGFNESNPDNKLPFLTLLIDEFGFTSEKMTRIKEEKELRRQIYTNIAGM
HHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALLARKTGIHLVVGLQKSSDELIPTTVRDMFTGRIAHRAESQSASQVALGNSDAYYLPST
HHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCC
PGRAILKIGNEFRIFQGAFYDPKKARAYLAKTSLRRDNRYYAEQQTNRLPTS
CCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]