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The map label for this gene is hisK [H]

Identifier: 134300416

GI number: 134300416

Start: 2806452

End: 2807264

Strand: Reverse

Name: hisK [H]

Synonym: Dred_2577

Alternate gene names: 134300416

Gene position: 2807264-2806452 (Counterclockwise)

Preceding gene: 134300418

Following gene: 134300415

Centisome position: 77.8

GC content: 41.08

Gene sequence:

>813_bases
ATGTTAACAGATTATCATATCCATGTAGAAAGAGGACCTTACACCGTGGATTGGCTGCGTCAATTTTATGAACAGGCTCA
GCAGGTAGGGATCAAAGACTGGGGAATATCCGAGCATGCCTATCGTTTTATTGAAACGAAGCATATTTTTTGGAACAACT
GGGTTGAACCACGGCAAACAGAGAAAATGGATGACTACCAGAACATGATTTTTAGGGCCAGAGCCGAAGGGATTAAAGTA
AAATTTGGTATCGAAATTGATTTTTTCCCAGGCAAAGAAAAGGAAATAAAAGAATTTATTGATCGCTATCCATTTGATTA
TGTGATAGGCTCTGTTCACTGGATTGATCAATGGGGTATTGATCTTTCGGAGATGAAGGAGGAATGGGAGCGTCGAAGGG
TTGAAGATGTATGGCTTGCTTATTTCGATCGAATTGAATCCTTAATTGAAAGTAATCTCTTTGATATTGCTGCGCACCTT
GATCTTGCTAAAATATTTAGCTATATTCCTACCAATCAAGAATTTCTCCAGGAACAATATAACAGGATCGCCCGGGTCCT
AGCGAAAAGGGGAACTTGTATAGAAATTAGTACTGCCGGATTAAGAAAACCTGTGGGCGAAATATATCCACATCCTTTGC
TACTGGAAACCTGCTTTGGACAGGGGGTACCCATTGTTATCAATTCCGATGCCCATTGTCCGGAAGACGTTGGGGCAGAC
TATGAAAGAGCCCTTGATCTGGCCAGAAAAATTGGTTACAAGAAGATACAAACCTTTACCAACAGGAAGGCAGAGAGTCA
TCTATTAGGCTAG

Upstream 100 bases:

>100_bases
AACAGGTGGTTAAGGAGGACATGTATACAGGAAGGTTTATTGATTTTTTCCTTGAGTCTTTATATAGTTGCTTTATTAAG
AGAAACAAGGTGGGTGACCA

Downstream 100 bases:

>100_bases
AAAATGGAATAATTGCTTGTATTTAGCAAAAAAGAAAAAGCCATATAAAATCACAACTCTAGTAAATGTCTCATAGATTG
ATAGAAAAAAGGGGTTGAGC

Product: HisJ family histidinol phosphate phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLTDYHIHVERGPYTVDWLRQFYEQAQQVGIKDWGISEHAYRFIETKHIFWNNWVEPRQTEKMDDYQNMIFRARAEGIKV
KFGIEIDFFPGKEKEIKEFIDRYPFDYVIGSVHWIDQWGIDLSEMKEEWERRRVEDVWLAYFDRIESLIESNLFDIAAHL
DLAKIFSYIPTNQEFLQEQYNRIARVLAKRGTCIEISTAGLRKPVGEIYPHPLLLETCFGQGVPIVINSDAHCPEDVGAD
YERALDLARKIGYKKIQTFTNRKAESHLLG

Sequences:

>Translated_270_residues
MLTDYHIHVERGPYTVDWLRQFYEQAQQVGIKDWGISEHAYRFIETKHIFWNNWVEPRQTEKMDDYQNMIFRARAEGIKV
KFGIEIDFFPGKEKEIKEFIDRYPFDYVIGSVHWIDQWGIDLSEMKEEWERRRVEDVWLAYFDRIESLIESNLFDIAAHL
DLAKIFSYIPTNQEFLQEQYNRIARVLAKRGTCIEISTAGLRKPVGEIYPHPLLLETCFGQGVPIVINSDAHCPEDVGAD
YERALDLARKIGYKKIQTFTNRKAESHLLG
>Mature_270_residues
MLTDYHIHVERGPYTVDWLRQFYEQAQQVGIKDWGISEHAYRFIETKHIFWNNWVEPRQTEKMDDYQNMIFRARAEGIKV
KFGIEIDFFPGKEKEIKEFIDRYPFDYVIGSVHWIDQWGIDLSEMKEEWERRRVEDVWLAYFDRIESLIESNLFDIAAHL
DLAKIFSYIPTNQEFLQEQYNRIARVLAKRGTCIEISTAGLRKPVGEIYPHPLLLETCFGQGVPIVINSDAHCPEDVGAD
YERALDLARKIGYKKIQTFTNRKAESHLLG

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31943; Mature: 31943

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDYHIHVERGPYTVDWLRQFYEQAQQVGIKDWGISEHAYRFIETKHIFWNNWVEPRQT
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
EKMDDYQNMIFRARAEGIKVKFGIEIDFFPGKEKEIKEFIDRYPFDYVIGSVHWIDQWGI
HHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHHHHHCC
DLSEMKEEWERRRVEDVWLAYFDRIESLIESNLFDIAAHLDLAKIFSYIPTNQEFLQEQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NRIARVLAKRGTCIEISTAGLRKPVGEIYPHPLLLETCFGQGVPIVINSDAHCPEDVGAD
HHHHHHHHCCCCEEEEECHHHHCCHHHHCCCHHHHHHHHCCCCCEEECCCCCCCHHCCCC
YERALDLARKIGYKKIQTFTNRKAESHLLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MLTDYHIHVERGPYTVDWLRQFYEQAQQVGIKDWGISEHAYRFIETKHIFWNNWVEPRQT
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
EKMDDYQNMIFRARAEGIKVKFGIEIDFFPGKEKEIKEFIDRYPFDYVIGSVHWIDQWGI
HHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHHHHHCC
DLSEMKEEWERRRVEDVWLAYFDRIESLIESNLFDIAAHLDLAKIFSYIPTNQEFLQEQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NRIARVLAKRGTCIEISTAGLRKPVGEIYPHPLLLETCFGQGVPIVINSDAHCPEDVGAD
HHHHHHHHCCCCEEEEECHHHHCCHHHHCCCHHHHHHHHCCCCCEEECCCCCCCHHCCCC
YERALDLARKIGYKKIQTFTNRKAESHLLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]