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The map label for this gene is clpX [H]

Identifier: 134300400

GI number: 134300400

Start: 2789456

End: 2790706

Strand: Reverse

Name: clpX [H]

Synonym: Dred_2561

Alternate gene names: 134300400

Gene position: 2790706-2789456 (Counterclockwise)

Preceding gene: 134300401

Following gene: 134300399

Centisome position: 77.35

GC content: 43.17

Gene sequence:

>1251_bases
ATGTTTAACGAGAAAGGCCAGCTCAAATGCTCCTTCTGTGGCAAAATGCAGGATCAGGTGAAAAAGCTTGTGGCCGGCCC
CGGAGTTTATATCTGCGATGAATGCATAGAGTTATGCAACGAAATCATCGAAGAAGAATTAAACGACGATTTGGGTATGG
ATATGGGCGATTTGCCAAAACCTAAAGAGATAAAAGACATTTTGGACCAGTATGTAATCGGCCAAGACAGTGCAAAAAGA
CAATTGGCTGTGGCAGTTTACAACCATTACAAACGTATTAACCTTGGGGGCAAAGTTGAAGACGTGGAACTCTCCAAGAG
TAACATTGTGATGTTGGGTCCCACGGGCTGTGGTAAAACGTTGCTGGCCCAGACGCTGGCTCGTCTGTTAAACGTGCCAT
TTGCCATCGCAGATGCCACCTCTTTGACTGAGGCAGGATATGTCGGTGAAGATGTGGAAAATATCCTGTTGAAGCTAATC
CAAGCAGCTGATTATGATGTAGAAAAGGCTGAAAAAGGTATTGTGTATATTGATGAAATTGATAAAATTGCCCGCAAATC
TGAAAACCCATCCATTACACGGGATGTTTCTGGTGAGGGTGTTCAGCAGGCATTGCTGAAAATTCTTGAGGGTACTGTTG
CCAGTGTGCCTCCCCAGGGTGGACGTAAGCATCCCCATCAAGAATTTATCCAGCTGGATACCACCAATATTCTGTTTATC
TGTGGTGGTGCCTTTGACGGAATTGATAAGATAATTCAAAATCGTACAGGTAAAAAACAGCTGGGCTTTGGAGCAGAAAT
TGAAACCCAAAAAGAAAAAAAGATTGGCGAAATCCTGGCCAACATTTTACCGGAAGACCTGCTGAAATTTGGTTTGATAC
CCGAGTTTGTAGGCCGCCTGCCGGTTATTGTTACCTTAGATGCTTTAGATGAAGAAGCACTGGTTCGTATATTAACAGAA
CCTAAAAATGCTTTAACCAAACAATACCAAAAGCTCTTTGAATTAGACGGTGTGGATTTGGAGTTGCAACCTGAATCTCT
GCGTGAGGTAGCCAAAGAGGCTCTCAAACGCAAAACCGGTGCAAGGGGTCTGCGTGCCATTATGGAAGAAGCCATGCTTG
GCATTATGTATGATATTCCTTCTCGGGAGGATATTTCAAAGGTTGTCATTACAAAGGATGCCATTTTGAAAAAGAGTGAA
CCTCTTCTTATCACAATGGACTCTAAAAAGAAAAAAGAAGAAAGCGCGTAG

Upstream 100 bases:

>100_bases
ACTGAGCGTGACTACTTTATGTCGGCCGAAGAAGCCAAGAAGTACGGACTCATCGACGAGGTGATGCCGTATCGGAAGTA
AAGATAAAAGAGGTGGAAAT

Downstream 100 bases:

>100_bases
CGTGCTGCCTAATAAAACACGGGGGGTATAAACCCCGTGTTTTTGCTTTTTAAAATAGTGGCTGTGAGCCATGGGCTTTT
AGCTGTTAGTACTGAGTTAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFNEKGQLKCSFCGKMQDQVKKLVAGPGVYICDECIELCNEIIEEELNDDLGMDMGDLPKPKEIKDILDQYVIGQDSAKR
QLAVAVYNHYKRINLGGKVEDVELSKSNIVMLGPTGCGKTLLAQTLARLLNVPFAIADATSLTEAGYVGEDVENILLKLI
QAADYDVEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFI
CGGAFDGIDKIIQNRTGKKQLGFGAEIETQKEKKIGEILANILPEDLLKFGLIPEFVGRLPVIVTLDALDEEALVRILTE
PKNALTKQYQKLFELDGVDLELQPESLREVAKEALKRKTGARGLRAIMEEAMLGIMYDIPSREDISKVVITKDAILKKSE
PLLITMDSKKKKEESA

Sequences:

>Translated_416_residues
MFNEKGQLKCSFCGKMQDQVKKLVAGPGVYICDECIELCNEIIEEELNDDLGMDMGDLPKPKEIKDILDQYVIGQDSAKR
QLAVAVYNHYKRINLGGKVEDVELSKSNIVMLGPTGCGKTLLAQTLARLLNVPFAIADATSLTEAGYVGEDVENILLKLI
QAADYDVEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFI
CGGAFDGIDKIIQNRTGKKQLGFGAEIETQKEKKIGEILANILPEDLLKFGLIPEFVGRLPVIVTLDALDEEALVRILTE
PKNALTKQYQKLFELDGVDLELQPESLREVAKEALKRKTGARGLRAIMEEAMLGIMYDIPSREDISKVVITKDAILKKSE
PLLITMDSKKKKEESA
>Mature_416_residues
MFNEKGQLKCSFCGKMQDQVKKLVAGPGVYICDECIELCNEIIEEELNDDLGMDMGDLPKPKEIKDILDQYVIGQDSAKR
QLAVAVYNHYKRINLGGKVEDVELSKSNIVMLGPTGCGKTLLAQTLARLLNVPFAIADATSLTEAGYVGEDVENILLKLI
QAADYDVEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFI
CGGAFDGIDKIIQNRTGKKQLGFGAEIETQKEKKIGEILANILPEDLLKFGLIPEFVGRLPVIVTLDALDEEALVRILTE
PKNALTKQYQKLFELDGVDLELQPESLREVAKEALKRKTGARGLRAIMEEAMLGIMYDIPSREDISKVVITKDAILKKSE
PLLITMDSKKKKEESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=348, Percent_Identity=49.4252873563218, Blast_Score=315, Evalue=6e-86,
Organism=Escherichia coli, GI1786642, Length=401, Percent_Identity=66.3341645885287, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=46.6019417475728, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=316, Percent_Identity=48.4177215189873, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=316, Percent_Identity=48.4177215189873, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=38.4039900249377, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.0438247011952, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=444, Percent_Identity=39.1891891891892, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=48.4276729559748, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=48.4276729559748, Blast_Score=298, Evalue=6e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45967; Mature: 45967

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEKGQLKCSFCGKMQDQVKKLVAGPGVYICDECIELCNEIIEEELNDDLGMDMGDLPK
CCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCC
PKEIKDILDQYVIGQDSAKRQLAVAVYNHYKRINLGGKVEDVELSKSNIVMLGPTGCGKT
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEEEECCCCCCHH
LLAQTLARLLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIVYIDEI
HHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEHHHH
DKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHEECCCCEEEE
CGGAFDGIDKIIQNRTGKKQLGFGAEIETQKEKKIGEILANILPEDLLKFGLIPEFVGRL
ECCCHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCHHHHCCC
PVIVTLDALDEEALVRILTEPKNALTKQYQKLFELDGVDLELQPESLREVAKEALKRKTG
CEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHC
ARGLRAIMEEAMLGIMYDIPSREDISKVVITKDAILKKSEPLLITMDSKKKKEESA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MFNEKGQLKCSFCGKMQDQVKKLVAGPGVYICDECIELCNEIIEEELNDDLGMDMGDLPK
CCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCC
PKEIKDILDQYVIGQDSAKRQLAVAVYNHYKRINLGGKVEDVELSKSNIVMLGPTGCGKT
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEEEECCCCCCHH
LLAQTLARLLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIVYIDEI
HHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEHHHH
DKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHEECCCCEEEE
CGGAFDGIDKIIQNRTGKKQLGFGAEIETQKEKKIGEILANILPEDLLKFGLIPEFVGRL
ECCCHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCHHHHCCC
PVIVTLDALDEEALVRILTEPKNALTKQYQKLFELDGVDLELQPESLREVAKEALKRKTG
CEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHC
ARGLRAIMEEAMLGIMYDIPSREDISKVVITKDAILKKSEPLLITMDSKKKKEESA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA