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The map label for this gene is minD [H]

Identifier: 134300382

GI number: 134300382

Start: 2766903

End: 2767697

Strand: Reverse

Name: minD [H]

Synonym: Dred_2543

Alternate gene names: 134300382

Gene position: 2767697-2766903 (Counterclockwise)

Preceding gene: 134300383

Following gene: 134300381

Centisome position: 76.71

GC content: 44.28

Gene sequence:

>795_bases
ATGGGTGAAGTTATCGTAGTCACTTCCGGTAAAGGGGGAGTTGGTAAAACCACCACCACGGCCAATCTGGGGACAGGTCT
TGCCTCCCATGGCAAGAAGGTGTGTCTGGTGGATGCCGATATTGGACTGCGTAACCTTGATGTTGTACTGGGTCTTGAAA
ACAGAATTGTATTTGATATAGTCGATGTTACCTCTGGCGTATGTCGCATGCGGCAGGCCTTAATTAAAGATAAGCGTTAT
GAAGGATTACACCTACTACCAGCAGCGCAAACCAAAGATAAAACTGCTGTTAGTCCTGAACAAATGGTAGAACTTACGGG
AGATTTAAAAAAGGAATTTGATTATGTCATCATTGATTGTCCGGCAGGTATTGAACAAGGCTTTAAAAATGCCATCGCTG
GAGCAGATAAAGCCATTGTTGTAACAACACCAGAAGTATCTGCTGTAAGGGATGCGGATCGGATCATAGGTTTATTGGAA
GCTGCTGAATTACGGGAACCCAAGTTGATCATTAACCGTTACCGGACCAAAATGGTTAACCGTGGGGACATGATGAGCAT
AGATGATATGAACGAAATATTAGCCATTGATCTCCTTGGTGTAGTGCCGGAGGACGAACAGGTTGTTGTAACAACAAACA
AGGGGGAGACCGTTGTCAGGGATGAGAGTTCCCAGAGTGGTCAGGCCTATCGCAATATAACTCGTCGCATTCTTGGGGAA
AATATTCCTTTAATGAGCTTAGAAGAACAGGCCGGATTTTTTAGTGCCCTAAGGAAAATGATTGGACTAAAGTAG

Upstream 100 bases:

>100_bases
AGTTACTATTGAAACCTTTAATTCCGTTCTTAAATAATTGTTACCTGTTGGGTTTAGGGGTTATGTTTTAAAGCATGGCA
TGATAAGGAGGACTTAAAAT

Downstream 100 bases:

>100_bases
GAAAGGGGGTACCGGTGTGTTAGAGTTTTTGAACAGGTTTTTTGGGCGAGAATCATCCAGTAGCAAGAATGTAGCCAAGG
AGAGACTGAGACTGGTATTG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGEVIVVTSGKGGVGKTTTTANLGTGLASHGKKVCLVDADIGLRNLDVVLGLENRIVFDIVDVTSGVCRMRQALIKDKRY
EGLHLLPAAQTKDKTAVSPEQMVELTGDLKKEFDYVIIDCPAGIEQGFKNAIAGADKAIVVTTPEVSAVRDADRIIGLLE
AAELREPKLIINRYRTKMVNRGDMMSIDDMNEILAIDLLGVVPEDEQVVVTTNKGETVVRDESSQSGQAYRNITRRILGE
NIPLMSLEEQAGFFSALRKMIGLK

Sequences:

>Translated_264_residues
MGEVIVVTSGKGGVGKTTTTANLGTGLASHGKKVCLVDADIGLRNLDVVLGLENRIVFDIVDVTSGVCRMRQALIKDKRY
EGLHLLPAAQTKDKTAVSPEQMVELTGDLKKEFDYVIIDCPAGIEQGFKNAIAGADKAIVVTTPEVSAVRDADRIIGLLE
AAELREPKLIINRYRTKMVNRGDMMSIDDMNEILAIDLLGVVPEDEQVVVTTNKGETVVRDESSQSGQAYRNITRRILGE
NIPLMSLEEQAGFFSALRKMIGLK
>Mature_263_residues
GEVIVVTSGKGGVGKTTTTANLGTGLASHGKKVCLVDADIGLRNLDVVLGLENRIVFDIVDVTSGVCRMRQALIKDKRYE
GLHLLPAAQTKDKTAVSPEQMVELTGDLKKEFDYVIIDCPAGIEQGFKNAIAGADKAIVVTTPEVSAVRDADRIIGLLEA
AELREPKLIINRYRTKMVNRGDMMSIDDMNEILAIDLLGVVPEDEQVVVTTNKGETVVRDESSQSGQAYRNITRRILGEN
IPLMSLEEQAGFFSALRKMIGLK

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=261, Percent_Identity=24.5210727969349, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787423, Length=271, Percent_Identity=47.9704797047971, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28685; Mature: 28553

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVIVVTSGKGGVGKTTTTANLGTGLASHGKKVCLVDADIGLRNLDVVLGLENRIVFDI
CCCEEEEECCCCCCCCCEEECCCCCCHHHCCCEEEEEECCCCCEEEEEEEECCCCEEEEE
VDVTSGVCRMRQALIKDKRYEGLHLLPAAQTKDKTAVSPEQMVELTGDLKKEFDYVIIDC
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFKNAIAGADKAIVVTTPEVSAVRDADRIIGLLEAAELREPKLIINRYRTKMVN
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
RGDMMSIDDMNEILAIDLLGVVPEDEQVVVTTNKGETVVRDESSQSGQAYRNITRRILGE
CCCCCCCCCHHHHHHHHHEECCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCC
NIPLMSLEEQAGFFSALRKMIGLK
CCCCEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEVIVVTSGKGGVGKTTTTANLGTGLASHGKKVCLVDADIGLRNLDVVLGLENRIVFDI
CCEEEEECCCCCCCCCEEECCCCCCHHHCCCEEEEEECCCCCEEEEEEEECCCCEEEEE
VDVTSGVCRMRQALIKDKRYEGLHLLPAAQTKDKTAVSPEQMVELTGDLKKEFDYVIIDC
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFKNAIAGADKAIVVTTPEVSAVRDADRIIGLLEAAELREPKLIINRYRTKMVN
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
RGDMMSIDDMNEILAIDLLGVVPEDEQVVVTTNKGETVVRDESSQSGQAYRNITRRILGE
CCCCCCCCCHHHHHHHHHEECCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCC
NIPLMSLEEQAGFFSALRKMIGLK
CCCCEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]