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The map label for this gene is mrdB [H]

Identifier: 134300380

GI number: 134300380

Start: 2765185

End: 2766423

Strand: Reverse

Name: mrdB [H]

Synonym: Dred_2541

Alternate gene names: 134300380

Gene position: 2766423-2765185 (Counterclockwise)

Preceding gene: 134300381

Following gene: 134300379

Centisome position: 76.67

GC content: 40.19

Gene sequence:

>1239_bases
ATGGTGGACAAGCGTTTTGTCAGAAACCTAGATTATACTTTACTTATTGCTGTAATACTGATTGTTTGTTTTAGTTTAGT
TATCATTAGCAGTGCAACTGTGGTCAGCAGCCCGATGGATTTTCGTCAGCATCAGGAAATGTGGAACAAGGATTCTTTGA
AGTACAATAACTATAATACAAGCCAACCCGTGAGTTTCTCTATCTTAAAGTATGCAAAAATTTTCTTCAGTGGTTTTGTT
CAAAAGCAGATCCTTTGGTTTCTAGCGGGTTTATTTGTGATGAGTATGGTAATTTCAATACCCTATGAGGATTTCCGACG
TCACAGGAAAACCATCTATGTTGTGAATATATTGTTGCTGTTAGTCGTGTTATCTCCTTTGGGACATAGTGCTAAGGGAG
CGACCCGTTGGATTGATTTAGGGGCCTTTAAACTACAGCCATCTGAATTTGCCAAAATCTTTATAATTATCACCTTTGCC
GATTTTCTAAGTAGGCGGGAGGGTAAATTAAAAACCTTTAAAGATTTAATTCCCTGCTTTGTTCATGTGGGCGTACCCAT
GTTATTGATATTAAAACAGCCAGACTTGGGAACCACACTGGTATTTGTAGCTATTATGTTTGGCATGCTGTATGTAGCAA
GTCCAAATACCAAGTTAATTGGGGGCTTGTTCCTGGGTGGTTGGACAACGGCCATAGGATGGGTTTGGTTACACTTTAAA
ATAGGGTTATGGGTTCCCTTAAAGGAATACCAGTTAGATCGTTTACTGGTTTTTATTGATCCTTGGAAGCAATGGCACGG
TGCCGGTTATCACGTGGTACAGTCCCAGATTGCCATTGGGTCCGGCGGTTTAGAAGGCAAAGGAATTTATAATGGGAGCC
AAAACCAGTTAAACTTCTTGCCCGAACAGCATACAGATTTTATCTTCTCGGTGGTGGGTGAGGAGATGGGTTTTATTGGA
GTTACAGCACTATTGATCCTCTTTTTTATTATTTTGTATCGAGGTATACGGATTGCATCAGAGGCTAGAGATTTGAATGG
TACATTATTAGCCACCGGAGTGCTTGGGATGCTAACCTCGCATATTTTAATCAACGTTGGCATGGTTTCAGGCATTATGC
CTGTAACGGGAGTTCCCTTGCCATTATTTAGTTACGGTGGCAGCAACATGCTAACCAACTTAATTGCCATTGGTATCTTG
CTAAATGTTTATATTCGAAGGCAAAAGATTGTGTTTTAG

Upstream 100 bases:

>100_bases
TAAGGCTTGCCGACCACTGATAATGGCTTAACCTTGCCCCCCTTTTTTTTTGAACCTGTGTATTATATAATTTATAGGTT
AAGGGGGTGTTCATCTTTAT

Downstream 100 bases:

>100_bases
CGTAGAAGTGGGGATGGGCTCTGTGGTTAAGTCATGAGCTTAAGAGATGACCTTTAGGGTGGGATGTGAGCCATAAGCAA
TGAGTTAAAAGTTTGTGTTA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MVDKRFVRNLDYTLLIAVILIVCFSLVIISSATVVSSPMDFRQHQEMWNKDSLKYNNYNTSQPVSFSILKYAKIFFSGFV
QKQILWFLAGLFVMSMVISIPYEDFRRHRKTIYVVNILLLLVVLSPLGHSAKGATRWIDLGAFKLQPSEFAKIFIIITFA
DFLSRREGKLKTFKDLIPCFVHVGVPMLLILKQPDLGTTLVFVAIMFGMLYVASPNTKLIGGLFLGGWTTAIGWVWLHFK
IGLWVPLKEYQLDRLLVFIDPWKQWHGAGYHVVQSQIAIGSGGLEGKGIYNGSQNQLNFLPEQHTDFIFSVVGEEMGFIG
VTALLILFFIILYRGIRIASEARDLNGTLLATGVLGMLTSHILINVGMVSGIMPVTGVPLPLFSYGGSNMLTNLIAIGIL
LNVYIRRQKIVF

Sequences:

>Translated_412_residues
MVDKRFVRNLDYTLLIAVILIVCFSLVIISSATVVSSPMDFRQHQEMWNKDSLKYNNYNTSQPVSFSILKYAKIFFSGFV
QKQILWFLAGLFVMSMVISIPYEDFRRHRKTIYVVNILLLLVVLSPLGHSAKGATRWIDLGAFKLQPSEFAKIFIIITFA
DFLSRREGKLKTFKDLIPCFVHVGVPMLLILKQPDLGTTLVFVAIMFGMLYVASPNTKLIGGLFLGGWTTAIGWVWLHFK
IGLWVPLKEYQLDRLLVFIDPWKQWHGAGYHVVQSQIAIGSGGLEGKGIYNGSQNQLNFLPEQHTDFIFSVVGEEMGFIG
VTALLILFFIILYRGIRIASEARDLNGTLLATGVLGMLTSHILINVGMVSGIMPVTGVPLPLFSYGGSNMLTNLIAIGIL
LNVYIRRQKIVF
>Mature_412_residues
MVDKRFVRNLDYTLLIAVILIVCFSLVIISSATVVSSPMDFRQHQEMWNKDSLKYNNYNTSQPVSFSILKYAKIFFSGFV
QKQILWFLAGLFVMSMVISIPYEDFRRHRKTIYVVNILLLLVVLSPLGHSAKGATRWIDLGAFKLQPSEFAKIFIIITFA
DFLSRREGKLKTFKDLIPCFVHVGVPMLLILKQPDLGTTLVFVAIMFGMLYVASPNTKLIGGLFLGGWTTAIGWVWLHFK
IGLWVPLKEYQLDRLLVFIDPWKQWHGAGYHVVQSQIAIGSGGLEGKGIYNGSQNQLNFLPEQHTDFIFSVVGEEMGFIG
VTALLILFFIILYRGIRIASEARDLNGTLLATGVLGMLTSHILINVGMVSGIMPVTGVPLPLFSYGGSNMLTNLIAIGIL
LNVYIRRQKIVF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=332, Percent_Identity=38.2530120481928, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786277, Length=329, Percent_Identity=31.6109422492401, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46296; Mature: 46296

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKRFVRNLDYTLLIAVILIVCFSLVIISSATVVSSPMDFRQHQEMWNKDSLKYNNYNT
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCEECCCCC
SQPVSFSILKYAKIFFSGFVQKQILWFLAGLFVMSMVISIPYEDFRRHRKTIYVVNILLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVVLSPLGHSAKGATRWIDLGAFKLQPSEFAKIFIIITFADFLSRREGKLKTFKDLIPCF
HHHHHCCCCCCCCCCCEEECCCEEECHHHHCEEEHHEEHHHHHHCCCCCHHHHHHHHHHH
VHVGVPMLLILKQPDLGTTLVFVAIMFGMLYVASPNTKLIGGLFLGGWTTAIGWVWLHFK
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHEEE
IGLWVPLKEYQLDRLLVFIDPWKQWHGAGYHVVQSQIAIGSGGLEGKGIYNGSQNQLNFL
EEEEEEHHHHCCCEEEEEEECHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PEQHTDFIFSVVGEEMGFIGVTALLILFFIILYRGIRIASEARDLNGTLLATGVLGMLTS
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHH
HILINVGMVSGIMPVTGVPLPLFSYGGSNMLTNLIAIGILLNVYIRRQKIVF
HHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDKRFVRNLDYTLLIAVILIVCFSLVIISSATVVSSPMDFRQHQEMWNKDSLKYNNYNT
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCEECCCCC
SQPVSFSILKYAKIFFSGFVQKQILWFLAGLFVMSMVISIPYEDFRRHRKTIYVVNILLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVVLSPLGHSAKGATRWIDLGAFKLQPSEFAKIFIIITFADFLSRREGKLKTFKDLIPCF
HHHHHCCCCCCCCCCCEEECCCEEECHHHHCEEEHHEEHHHHHHCCCCCHHHHHHHHHHH
VHVGVPMLLILKQPDLGTTLVFVAIMFGMLYVASPNTKLIGGLFLGGWTTAIGWVWLHFK
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHEEE
IGLWVPLKEYQLDRLLVFIDPWKQWHGAGYHVVQSQIAIGSGGLEGKGIYNGSQNQLNFL
EEEEEEHHHHCCCEEEEEEECHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PEQHTDFIFSVVGEEMGFIGVTALLILFFIILYRGIRIASEARDLNGTLLATGVLGMLTS
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHH
HILINVGMVSGIMPVTGVPLPLFSYGGSNMLTNLIAIGILLNVYIRRQKIVF
HHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]