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The map label for this gene is yqeV [H]

Identifier: 134300331

GI number: 134300331

Start: 2711132

End: 2712442

Strand: Reverse

Name: yqeV [H]

Synonym: Dred_2492

Alternate gene names: 134300331

Gene position: 2712442-2711132 (Counterclockwise)

Preceding gene: 134300332

Following gene: 134300330

Centisome position: 75.18

GC content: 45.54

Gene sequence:

>1311_bases
ATGGCTAAATCTGCTGCTATTTATACCCTTGGATGTAAAGTTAACCAGTATGAATCATCTGCCATCGCCGATTTATTTCG
GCAAGCGGGCTACGAAATAGTTGATTTTGAGCAACATGCAGATGCATATGTAATCAATACCTGCACCGTTACCCACATGG
GGGATCGCAAATCCAGGCAAATCATCCGACGGGCCAGTAAACAGAACCCAGCGGCTGTTATTACAGTAACGGGATGTTAT
GCCCAGACATCACCCGGAGAAGTATTAGAAATTCCTGGTGTTGATCTGGTAGTTGGCACCAAGGATAAAAGTAGAATTGT
CCAACTGGTGGAGGCCTACTCCAGGGGTAAAGGGCCGGTTAATGCAGTGGATGATATTATGCAAACTGATTGCTTTGAAG
AGCTTCCGGTACCCACAGAACAAGGAAAAACAAGGGCTTTTCTAAAGATTCAGGAGGGATGCAACAGCTTTTGTGCTTAC
TGCATTATTCCTTATGCCCGGGGGCCCGTACGTAGCCGACTGCCGGAAAATGTCCTGAGTTCTGCAGAAGAATTAATTCA
ACAGGGTTTTCAAGAGATTGTATTAACTGGCATTCATATCGGTGCCTATGGTCAGGATTTTACCGGAAAAGATATTGATT
TGGGCTGGTTGGTGGAGCGGTTAGCGAAATTACCAGGCCTAACCAGACTTCGTTTGGGTTCTGTGGAACCCCATGATATC
AACAATGCCCTCATTAAAGCCGTGTCAGAGCATCCCAATGTGTGCCGCCATCTGCATATTCCTTTACAAAGCGGTGATGA
TGAGATTCTGGCTCTCATGGGAAGGAGGTACAACACCCAGCAATTTACTGACTTAATTCATAAAATAAACCAGATTATGC
CGGGTATTGCTATCACCAGCGACATTATTGTTGGCTTTCCTGGGGAAACCCAGGAACATTTTCAAAACACACTAAAAACC
GTTGAACGGTCTGGCTTTGCCGGTATCCATGTCTTTAAATACTCTCCTCGCAAGGGTACGCCCGCCGCAGAGATGACAGA
TCAGGTTGCTCCCCAAGACAAAGAAGAGCGTAGTAAAAGTTTGATTGAACTGGGTAATCGCCTTGCTCATCAATTTGCCC
AGCAACAGGTGGGTAAAGAACTGAAAGTGCTGGTGGAACAACCCTACGAAAAGGACCCTAATCTTTTGGAAGGGCATACA
GACACCTACCTTAAGGTGCTATTTCCAGGGGACACAGGCTTGAAGGGACAAATGGTGAGGGTGCACATCCAAGGAGTTAA
GGAATCTACATTAAAAGGCAGAATTATTTAA

Upstream 100 bases:

>100_bases
ACACTGGGCAGCCGGATTTTGCGCACTGAAACAGCAGGACCAGCGGCTCTGACAATGGTCCTGTACCAGTTTGGCGAACT
GGGCTAAGGAGGTTTCCAAT

Downstream 100 bases:

>100_bases
CAAGGTTGCAGGATAATATCCTTTGAGTGTTGAATACACTTTTAGGAAAGACTATGTAAAAATAGTTTTAATTTACGCTG
GGGGGAGGTGCTTGCTGGTG

Product: RNA modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MAKSAAIYTLGCKVNQYESSAIADLFRQAGYEIVDFEQHADAYVINTCTVTHMGDRKSRQIIRRASKQNPAAVITVTGCY
AQTSPGEVLEIPGVDLVVGTKDKSRIVQLVEAYSRGKGPVNAVDDIMQTDCFEELPVPTEQGKTRAFLKIQEGCNSFCAY
CIIPYARGPVRSRLPENVLSSAEELIQQGFQEIVLTGIHIGAYGQDFTGKDIDLGWLVERLAKLPGLTRLRLGSVEPHDI
NNALIKAVSEHPNVCRHLHIPLQSGDDEILALMGRRYNTQQFTDLIHKINQIMPGIAITSDIIVGFPGETQEHFQNTLKT
VERSGFAGIHVFKYSPRKGTPAAEMTDQVAPQDKEERSKSLIELGNRLAHQFAQQQVGKELKVLVEQPYEKDPNLLEGHT
DTYLKVLFPGDTGLKGQMVRVHIQGVKESTLKGRII

Sequences:

>Translated_436_residues
MAKSAAIYTLGCKVNQYESSAIADLFRQAGYEIVDFEQHADAYVINTCTVTHMGDRKSRQIIRRASKQNPAAVITVTGCY
AQTSPGEVLEIPGVDLVVGTKDKSRIVQLVEAYSRGKGPVNAVDDIMQTDCFEELPVPTEQGKTRAFLKIQEGCNSFCAY
CIIPYARGPVRSRLPENVLSSAEELIQQGFQEIVLTGIHIGAYGQDFTGKDIDLGWLVERLAKLPGLTRLRLGSVEPHDI
NNALIKAVSEHPNVCRHLHIPLQSGDDEILALMGRRYNTQQFTDLIHKINQIMPGIAITSDIIVGFPGETQEHFQNTLKT
VERSGFAGIHVFKYSPRKGTPAAEMTDQVAPQDKEERSKSLIELGNRLAHQFAQQQVGKELKVLVEQPYEKDPNLLEGHT
DTYLKVLFPGDTGLKGQMVRVHIQGVKESTLKGRII
>Mature_435_residues
AKSAAIYTLGCKVNQYESSAIADLFRQAGYEIVDFEQHADAYVINTCTVTHMGDRKSRQIIRRASKQNPAAVITVTGCYA
QTSPGEVLEIPGVDLVVGTKDKSRIVQLVEAYSRGKGPVNAVDDIMQTDCFEELPVPTEQGKTRAFLKIQEGCNSFCAYC
IIPYARGPVRSRLPENVLSSAEELIQQGFQEIVLTGIHIGAYGQDFTGKDIDLGWLVERLAKLPGLTRLRLGSVEPHDIN
NALIKAVSEHPNVCRHLHIPLQSGDDEILALMGRRYNTQQFTDLIHKINQIMPGIAITSDIIVGFPGETQEHFQNTLKTV
ERSGFAGIHVFKYSPRKGTPAAEMTDQVAPQDKEERSKSLIELGNRLAHQFAQQQVGKELKVLVEQPYEKDPNLLEGHTD
TYLKVLFPGDTGLKGQMVRVHIQGVKESTLKGRII

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=439, Percent_Identity=31.6628701594533, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI28872784, Length=471, Percent_Identity=26.1146496815287, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI28872782, Length=473, Percent_Identity=26.0042283298097, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1786882, Length=443, Percent_Identity=32.9571106094808, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1787057, Length=449, Percent_Identity=30.2895322939866, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17553146, Length=466, Percent_Identity=26.8240343347639, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71996771, Length=362, Percent_Identity=28.7292817679558, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21356207, Length=470, Percent_Identity=25.9574468085106, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI19922432, Length=438, Percent_Identity=30.5936073059361, Blast_Score=178, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48304; Mature: 48173

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSAAIYTLGCKVNQYESSAIADLFRQAGYEIVDFEQHADAYVINTCTVTHMGDRKSRQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEHHCCCCEEEEEEEEEEECCCHHHHH
IIRRASKQNPAAVITVTGCYAQTSPGEVLEIPGVDLVVGTKDKSRIVQLVEAYSRGKGPV
HHHHHHCCCCEEEEEEEECEECCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCC
NAVDDIMQTDCFEELPVPTEQGKTRAFLKIQEGCNSFCAYCIIPYARGPVRSRLPENVLS
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHCHHHHHH
SAEELIQQGFQEIVLTGIHIGAYGQDFTGKDIDLGWLVERLAKLPGLTRLRLGSVEPHDI
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCH
NNALIKAVSEHPNVCRHLHIPLQSGDDEILALMGRRYNTQQFTDLIHKINQIMPGIAITS
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEC
DIIVGFPGETQEHFQNTLKTVERSGFAGIHVFKYSPRKGTPAAEMTDQVAPQDKEERSKS
CEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHH
LIELGNRLAHQFAQQQVGKELKVLVEQPYEKDPNLLEGHTDTYLKVLFPGDTGLKGQMVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
VHIQGVKESTLKGRII
EEEECCHHHCCCCCCC
>Mature Secondary Structure 
AKSAAIYTLGCKVNQYESSAIADLFRQAGYEIVDFEQHADAYVINTCTVTHMGDRKSRQ
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEHHCCCCEEEEEEEEEEECCCHHHHH
IIRRASKQNPAAVITVTGCYAQTSPGEVLEIPGVDLVVGTKDKSRIVQLVEAYSRGKGPV
HHHHHHCCCCEEEEEEEECEECCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCC
NAVDDIMQTDCFEELPVPTEQGKTRAFLKIQEGCNSFCAYCIIPYARGPVRSRLPENVLS
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHCHHHHHH
SAEELIQQGFQEIVLTGIHIGAYGQDFTGKDIDLGWLVERLAKLPGLTRLRLGSVEPHDI
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCH
NNALIKAVSEHPNVCRHLHIPLQSGDDEILALMGRRYNTQQFTDLIHKINQIMPGIAITS
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEC
DIIVGFPGETQEHFQNTLKTVERSGFAGIHVFKYSPRKGTPAAEMTDQVAPQDKEERSKS
CEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHH
LIELGNRLAHQFAQQQVGKELKVLVEQPYEKDPNLLEGHTDTYLKVLFPGDTGLKGQMVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
VHIQGVKESTLKGRII
EEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]