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The map label for this gene is engD [H]

Identifier: 134300054

GI number: 134300054

Start: 2419497

End: 2420597

Strand: Reverse

Name: engD [H]

Synonym: Dred_2210

Alternate gene names: 134300054

Gene position: 2420597-2419497 (Counterclockwise)

Preceding gene: 134300056

Following gene: 134300053

Centisome position: 67.09

GC content: 43.6

Gene sequence:

>1101_bases
ATGTCAACTAACCTTATAAGTGGGATAATCGGTCTGCCGATGGTGGGAAAAACAACAATCTTTAATTTATTAACCAATTC
CAACCAGGAAGTATCAAATTTTTTAAGTGGAAAAACCGAAACAATCACTGCATCTGCGAGAGTGCCTGATAAGAGAATTG
ATTTTTTAGTGAATATGTACAAGCCACGAAAGATTACCTATGCTCAAATTCAATTCAGTGAAGTGCCTGGATTAGTGCGG
GGAGCCAGCGAAGGAAAAGGAGTTGGCAATCAATTCCTCAGTGCCATTCGAAATGCTGATCTGCTGGTACATGTTGTAAG
GGCCTATCAGAATCCCGACGTTCCCCACGTAGAAGACGAAATTAACCCCCTGCGGGATATAGAAACCATTGCTGTGGAGA
TTTTATTGGCAGATATGGATCTGGTGGAAAAAAGAATCCAAAGAATCCAGTCTGGCAAAAAAATTACCAAAGAGAATGCC
TTTGAGCTAGAAGTATTAAAAAAATGTCTGCAGGCACTGGAAGAAGAGACGCCCATCAGCCAATTGGGGCTAACCGAAGA
AGAAAAATTAACATTAAAAAACTATTCCTTTTTAACAGAAAAACCGATGCTGCTGGTGATAAACATAGATGAAGATCAAT
TTAGGGAGGGTAGCTATCCCACTAAAGAAGAAGTAGAAAAATACGCTGCTGAAAAGGGAATTGCTGTAACAGAAATCTGC
GGTCGCATAGAAATGGAGATCAGTCAACTGCCGGAAGCTGACAGGCTTCTCTTTATGGAAGACCTGGGGACGAACGAACC
GGGCATTGATCGTTTGGCCAGGGCGGTGTATGATTACCTGGGTTTAATTTCTTTCCTTACCGCCGGGGAAGATGAAGTAC
GGGCCTGGACCATCAAACGTAACACCGATGCCAAAAGGGCGGCGGGTAAGATTCACTCCGATATTGAGCGGGGCTTTATT
AGGGCAGAAGTGATTGCCTTTGAAGATTTGGCATCCACAGGTTCTCTGGCCAAAGCCCGGGAAAAGGGCCTGCTGCGCTT
AGAGGGAAAAGAGTATGTTGTACAGGATGGCGATATTATCAACTTTCGATTTAACGTGTAG

Upstream 100 bases:

>100_bases
AAACATTGCAAAAAATGTCATTCTGAATGAAACATTCATGGACCTATGTAGCAAAGGGTTGAGAGATGTGATAAAATTCT
GAACAACAGAGGTGATGAAT

Downstream 100 bases:

>100_bases
ATATGTGGCAGCTCTTTATCTTTAGGGCTGCCCATTTGTTTTAGCCCTGTATGCATACCCCTATTCCTGAGTTAAAATAT
ATCAAGTAGCTTTTTACAGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSTNLISGIIGLPMVGKTTIFNLLTNSNQEVSNFLSGKTETITASARVPDKRIDFLVNMYKPRKITYAQIQFSEVPGLVR
GASEGKGVGNQFLSAIRNADLLVHVVRAYQNPDVPHVEDEINPLRDIETIAVEILLADMDLVEKRIQRIQSGKKITKENA
FELEVLKKCLQALEEETPISQLGLTEEEKLTLKNYSFLTEKPMLLVINIDEDQFREGSYPTKEEVEKYAAEKGIAVTEIC
GRIEMEISQLPEADRLLFMEDLGTNEPGIDRLARAVYDYLGLISFLTAGEDEVRAWTIKRNTDAKRAAGKIHSDIERGFI
RAEVIAFEDLASTGSLAKAREKGLLRLEGKEYVVQDGDIINFRFNV

Sequences:

>Translated_366_residues
MSTNLISGIIGLPMVGKTTIFNLLTNSNQEVSNFLSGKTETITASARVPDKRIDFLVNMYKPRKITYAQIQFSEVPGLVR
GASEGKGVGNQFLSAIRNADLLVHVVRAYQNPDVPHVEDEINPLRDIETIAVEILLADMDLVEKRIQRIQSGKKITKENA
FELEVLKKCLQALEEETPISQLGLTEEEKLTLKNYSFLTEKPMLLVINIDEDQFREGSYPTKEEVEKYAAEKGIAVTEIC
GRIEMEISQLPEADRLLFMEDLGTNEPGIDRLARAVYDYLGLISFLTAGEDEVRAWTIKRNTDAKRAAGKIHSDIERGFI
RAEVIAFEDLASTGSLAKAREKGLLRLEGKEYVVQDGDIINFRFNV
>Mature_365_residues
STNLISGIIGLPMVGKTTIFNLLTNSNQEVSNFLSGKTETITASARVPDKRIDFLVNMYKPRKITYAQIQFSEVPGLVRG
ASEGKGVGNQFLSAIRNADLLVHVVRAYQNPDVPHVEDEINPLRDIETIAVEILLADMDLVEKRIQRIQSGKKITKENAF
ELEVLKKCLQALEEETPISQLGLTEEEKLTLKNYSFLTEKPMLLVINIDEDQFREGSYPTKEEVEKYAAEKGIAVTEICG
RIEMEISQLPEADRLLFMEDLGTNEPGIDRLARAVYDYLGLISFLTAGEDEVRAWTIKRNTDAKRAAGKIHSDIERGFIR
AEVIAFEDLASTGSLAKAREKGLLRLEGKEYVVQDGDIINFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=376, Percent_Identity=36.1702127659575, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI58761502, Length=179, Percent_Identity=38.5474860335196, Blast_Score=129, Evalue=6e-30,
Organism=Escherichia coli, GI1787454, Length=361, Percent_Identity=43.7673130193906, Blast_Score=311, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI17509631, Length=371, Percent_Identity=37.466307277628, Blast_Score=260, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=33.6, Blast_Score=182, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6321773, Length=388, Percent_Identity=30.4123711340206, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321649, Length=231, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640873, Length=377, Percent_Identity=36.604774535809, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24640877, Length=377, Percent_Identity=36.604774535809, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24640875, Length=377, Percent_Identity=36.604774535809, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24640879, Length=335, Percent_Identity=36.1194029850746, Blast_Score=204, Evalue=7e-53,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41042; Mature: 40910

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNLISGIIGLPMVGKTTIFNLLTNSNQEVSNFLSGKTETITASARVPDKRIDFLVNMY
CCCHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
KPRKITYAQIQFSEVPGLVRGASEGKGVGNQFLSAIRNADLLVHVVRAYQNPDVPHVEDE
CCCEEEEEEEEHHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHH
INPLRDIETIAVEILLADMDLVEKRIQRIQSGKKITKENAFELEVLKKCLQALEEETPIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCHH
QLGLTEEEKLTLKNYSFLTEKPMLLVINIDEDQFREGSYPTKEEVEKYAAEKGIAVTEIC
HHCCCCHHHEEECCCCEECCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
GRIEMEISQLPEADRLLFMEDLGTNEPGIDRLARAVYDYLGLISFLTAGEDEVRAWTIKR
HHHHHHHHHCCCHHHEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
NTDAKRAAGKIHSDIERGFIRAEVIAFEDLASTGSLAKAREKGLLRLEGKEYVVQDGDII
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCEEEEECCCEE
NFRFNV
EEEECC
>Mature Secondary Structure 
STNLISGIIGLPMVGKTTIFNLLTNSNQEVSNFLSGKTETITASARVPDKRIDFLVNMY
CCHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
KPRKITYAQIQFSEVPGLVRGASEGKGVGNQFLSAIRNADLLVHVVRAYQNPDVPHVEDE
CCCEEEEEEEEHHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHH
INPLRDIETIAVEILLADMDLVEKRIQRIQSGKKITKENAFELEVLKKCLQALEEETPIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCHH
QLGLTEEEKLTLKNYSFLTEKPMLLVINIDEDQFREGSYPTKEEVEKYAAEKGIAVTEIC
HHCCCCHHHEEECCCCEECCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
GRIEMEISQLPEADRLLFMEDLGTNEPGIDRLARAVYDYLGLISFLTAGEDEVRAWTIKR
HHHHHHHHHCCCHHHEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
NTDAKRAAGKIHSDIERGFIRAEVIAFEDLASTGSLAKAREKGLLRLEGKEYVVQDGDII
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCEEEEECCCEE
NFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]