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The map label for this gene is nuoA

Identifier: 134299892

GI number: 134299892

Start: 2245078

End: 2245431

Strand: Reverse

Name: nuoA

Synonym: Dred_2046

Alternate gene names: 134299892

Gene position: 2245431-2245078 (Counterclockwise)

Preceding gene: 134299893

Following gene: 134299891

Centisome position: 62.23

GC content: 40.68

Gene sequence:

>354_bases
TTGTCAGATTGGATAGGAGTGGCTTTGTTTATCGTGGTTGGTATTGTCTTTGGCGCCGGTGGGATGTTGACAAGCTTCCT
TATTCATCCTCGCAGCAAAAATAAATTTAAGCTGGAAACCTATGAATGTGGGCTGCCAACAGAAGGCGCCACATGGGTGC
GCTTTAAGACGCAGTATTTTACCTATGCCTTGATGTTTGTCATTTTTGATGTGGAAGTAATTTATCTTTATCCTTGGGCT
GTCAGTTTTGTAGATCTTGGTTTGGCAGGACTTATTAAAATGTTTCTTTTCATCTTTATTCTTGTTTTAGGACTTTGGTA
TGCCTGGAAGGAAGGTGCACTTGAGTGGAAATAA

Upstream 100 bases:

>100_bases
AATAGTTGGCTAAGATTTTGCATTTTACATAAGTGGAAATAATTTTAGATTATTTCTATTGCAATACAGCTATTTAAATT
TTAAGAAAGGAGTGTATAAA

Downstream 100 bases:

>100_bases
AGGATCAAGACAAAGCCGCCAACCCGGTAGCTAAAGATGAGATGTATGAGGAAACCGTAAAACGTTTAAAAAAGCTAGGG
GCTGAACCGGCTGTCATCGG

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MSDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYFTYALMFVIFDVEVIYLYPWA
VSFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK

Sequences:

>Translated_117_residues
MSDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYFTYALMFVIFDVEVIYLYPWA
VSFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK
>Mature_116_residues
SDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYFTYALMFVIFDVEVIYLYPWAV
SFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=109, Percent_Identity=32.1100917431193, Blast_Score=69, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_DESRM (A4J660)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113388.1
- STRING:   A4J660
- GeneID:   4958164
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2046
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   GERELTY
- PhylomeDB:   A4J660
- ProtClustDB:   CLSK2537094
- BioCyc:   DRED349161:DRED_2046-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13466; Mature: 13335

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfddf798)-; HASH(0xf8d71bc)-; HASH(0xf597d90)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHH
TYALMFVIFDVEVIYLYPWAVSFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK
HHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
SDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYF
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHH
TYALMFVIFDVEVIYLYPWAVSFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK
HHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA