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The map label for this gene is 134299849

Identifier: 134299849

GI number: 134299849

Start: 2200669

End: 2201619

Strand: Reverse

Name: 134299849

Synonym: Dred_2002

Alternate gene names: NA

Gene position: 2201619-2200669 (Counterclockwise)

Preceding gene: 134299850

Following gene: 134299846

Centisome position: 61.02

GC content: 39.96

Gene sequence:

>951_bases
ATGAACAACAGTAAGTTACCAAAGGTAAAACCTATGTTAGCTGTACCAGCAGACCCCTTTGATAGCAATGATTACTTATA
TGAAATAAAATGGGATGGTTACCGTGGGTTAGTCTATCTAAGTGAGCAAACAACCATTCTCTCAAGAAATTTAATAAATC
TCACGGAAAGGTTTCCCGAATTGCAAAATTTACATAAAAAAGTTATACAGAAACCAGCCATATTGGATGGAGAAATTGTA
GTGCTGGAGGAAGGTAAACCATCCTTTAGCAAACTTCAATCTAGGGGAAAGATAACGGATGCTTTAAAAGTGAATCAGCT
ATCCAGACGTTTTCCTGTAAGCTTTATTGCCTTTGATGTTTTATACAAAGACGGCGAGAGTATTATGAATTTACCACTGG
AGAGCAGAAAAAAAGTCCTTGAGGATATTATAGAGCCGGGAACCCATTTGATTGTATCTCAATATGTACATGGTTCGGGT
ATTAAATTTTATGAAGCAGTTCAGAAAGTTGGGCTTGAGGGAATGATGGCGAAACGGTTAGATAGTTTATACATGCCTGG
GAAAAGGTCACCAGTCTGGAAAAAAGTACGCAATACTCATTCGGCAGAATGGGTTATTGCCGGTTGGGAAAAGGGAGAAG
GTCACCGGCATCTAGGTTCCCTGATACTAGTTGGTTTTAATCAAGGTAAATGGATATACATGGGGAAGGTAGGGACCGGC
TTTGGCAAAGATGACGAGAACAAATTATTGAGACTAATGGAACCATTAGAGATTGATGAATCGGTTTTTACTCCCCCTAG
GGGAGAGTTTCGATCTCCTGTTTGGGTTAAACCGACATTAATTTGCGAAGTGACATTTACCGAAATCAGTCCAGAGGGTA
GATTGAGGCACCCCAGTTATAAAGGACTACGGTATGATAAGAACCCGCAGGAATGCACAATAGATCAATAG

Upstream 100 bases:

>100_bases
CAAACAGGAAAGGGATAACGCATTAAAGAAAGATGCCACTAAAAAGAAAACCACCAGGACAAAAAAGGCCACGGCCTCGT
AAAAGGGGACAAGGATTGGC

Downstream 100 bases:

>100_bases
TAAAAACACAACCGGGTGGTTGTGTTTTATATTTTTAGCCTATATTTTTGGGCTCTGTAAAGTAAGGCAGAGCGGGTTAT
ACCCAGTAATTGGGCAGCCC

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNNSKLPKVKPMLAVPADPFDSNDYLYEIKWDGYRGLVYLSEQTTILSRNLINLTERFPELQNLHKKVIQKPAILDGEIV
VLEEGKPSFSKLQSRGKITDALKVNQLSRRFPVSFIAFDVLYKDGESIMNLPLESRKKVLEDIIEPGTHLIVSQYVHGSG
IKFYEAVQKVGLEGMMAKRLDSLYMPGKRSPVWKKVRNTHSAEWVIAGWEKGEGHRHLGSLILVGFNQGKWIYMGKVGTG
FGKDDENKLLRLMEPLEIDESVFTPPRGEFRSPVWVKPTLICEVTFTEISPEGRLRHPSYKGLRYDKNPQECTIDQ

Sequences:

>Translated_316_residues
MNNSKLPKVKPMLAVPADPFDSNDYLYEIKWDGYRGLVYLSEQTTILSRNLINLTERFPELQNLHKKVIQKPAILDGEIV
VLEEGKPSFSKLQSRGKITDALKVNQLSRRFPVSFIAFDVLYKDGESIMNLPLESRKKVLEDIIEPGTHLIVSQYVHGSG
IKFYEAVQKVGLEGMMAKRLDSLYMPGKRSPVWKKVRNTHSAEWVIAGWEKGEGHRHLGSLILVGFNQGKWIYMGKVGTG
FGKDDENKLLRLMEPLEIDESVFTPPRGEFRSPVWVKPTLICEVTFTEISPEGRLRHPSYKGLRYDKNPQECTIDQ
>Mature_316_residues
MNNSKLPKVKPMLAVPADPFDSNDYLYEIKWDGYRGLVYLSEQTTILSRNLINLTERFPELQNLHKKVIQKPAILDGEIV
VLEEGKPSFSKLQSRGKITDALKVNQLSRRFPVSFIAFDVLYKDGESIMNLPLESRKKVLEDIIEPGTHLIVSQYVHGSG
IKFYEAVQKVGLEGMMAKRLDSLYMPGKRSPVWKKVRNTHSAEWVIAGWEKGEGHRHLGSLILVGFNQGKWIYMGKVGTG
FGKDDENKLLRLMEPLEIDESVFTPPRGEFRSPVWVKPTLICEVTFTEISPEGRLRHPSYKGLRYDKNPQECTIDQ

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=361, Percent_Identity=26.0387811634349, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320038, Length=360, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 36089; Mature: 36089

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSKLPKVKPMLAVPADPFDSNDYLYEIKWDGYRGLVYLSEQTTILSRNLINLTERFPE
CCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHCHH
LQNLHKKVIQKPAILDGEIVVLEEGKPSFSKLQSRGKITDALKVNQLSRRFPVSFIAFDV
HHHHHHHHHCCCCEECCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEHH
LYKDGESIMNLPLESRKKVLEDIIEPGTHLIVSQYVHGSGIKFYEAVQKVGLEGMMAKRL
HHHCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHCHHHHHHHHH
DSLYMPGKRSPVWKKVRNTHSAEWVIAGWEKGEGHRHLGSLILVGFNQGKWIYMGKVGTG
HHHCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEECEEEEEEECCCCEEEEECCCCC
FGKDDENKLLRLMEPLEIDESVFTPPRGEFRSPVWVKPTLICEVTFTEISPEGRLRHPSY
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEEEEECCCCCCCCCCC
KGLRYDKNPQECTIDQ
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNSKLPKVKPMLAVPADPFDSNDYLYEIKWDGYRGLVYLSEQTTILSRNLINLTERFPE
CCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHCHH
LQNLHKKVIQKPAILDGEIVVLEEGKPSFSKLQSRGKITDALKVNQLSRRFPVSFIAFDV
HHHHHHHHHCCCCEECCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEHH
LYKDGESIMNLPLESRKKVLEDIIEPGTHLIVSQYVHGSGIKFYEAVQKVGLEGMMAKRL
HHHCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHCHHHHHHHHH
DSLYMPGKRSPVWKKVRNTHSAEWVIAGWEKGEGHRHLGSLILVGFNQGKWIYMGKVGTG
HHHCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEECEEEEEEECCCCEEEEECCCCC
FGKDDENKLLRLMEPLEIDESVFTPPRGEFRSPVWVKPTLICEVTFTEISPEGRLRHPSY
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEEEEECCCCCCCCCCC
KGLRYDKNPQECTIDQ
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]