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The map label for this gene is cobP [H]

Identifier: 134299760

GI number: 134299760

Start: 2100411

End: 2100968

Strand: Reverse

Name: cobP [H]

Synonym: Dred_1910

Alternate gene names: 134299760

Gene position: 2100968-2100411 (Counterclockwise)

Preceding gene: 134299762

Following gene: 134299758

Centisome position: 58.23

GC content: 42.29

Gene sequence:

>558_bases
TTGAAAGAGAACAAACTTATTTTGGTTTTGGGAGGAACCCGAAGCGGTAAAAGTCAGTATGCTGAAAAAATAGCTAAGAT
ACAGGGACAAAGGGTTCTTTACCTGGCCACAGCAACCGTTAATGATAATGAAATGAAGAGGCGTGTAAGGTTACACCAGG
AAAGAAGGCCCGATGCCTGGGACACCCGGGAGGAACCCATAAAGGTAACGCAGGTCATAAATGAATTGGGGGACAGTTAT
GATGTAATATTACTGGACTGTCTCACTCTTTGGATAACCAATCTTTTGTTAGAAAACCAGAATATTAATGAAGCCCATTT
AGCTGAAAAAGAAAAACAAATTTTGCAGGAAGCCAGTGAGCTGGCGCTTGTTTGTTCAAAGACTAATGCAACAGTCATAG
TTGTAAGCAATGAGGTAGGTTTGAGTATTGTGCCGGAGTATCCTTTGGGGCGGGTATTTAGGGATATAAGTGGCCTAGCC
AATCAGATCTTTGCCCAAAGGGCCAGTGAGGTTTATTTTGTGGCTGCAGGACTACCCCTTTCATTAAAAGGTAATTAG

Upstream 100 bases:

>100_bases
TTATATTGAATAGCAGGATTTTAGAGACTTTGGCAAGAACCATAATCATATCCATGATAATGAATTAAAGAAAAGAAAGC
AATGGAAAAGGAGAGCGGTC

Downstream 100 bases:

>100_bases
GACTATGACTAAGCCCAGCGGTGATATGTCAAGAGAATGATTCTAAAAAATTGGAAATTAATTTAACAAAAGTGTACCCT
ATACCCTAAAAAAGGGTATA

Product: adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKENKLILVLGGTRSGKSQYAEKIAKIQGQRVLYLATATVNDNEMKRRVRLHQERRPDAWDTREEPIKVTQVINELGDSY
DVILLDCLTLWITNLLLENQNINEAHLAEKEKQILQEASELALVCSKTNATVIVVSNEVGLSIVPEYPLGRVFRDISGLA
NQIFAQRASEVYFVAAGLPLSLKGN

Sequences:

>Translated_185_residues
MKENKLILVLGGTRSGKSQYAEKIAKIQGQRVLYLATATVNDNEMKRRVRLHQERRPDAWDTREEPIKVTQVINELGDSY
DVILLDCLTLWITNLLLENQNINEAHLAEKEKQILQEASELALVCSKTNATVIVVSNEVGLSIVPEYPLGRVFRDISGLA
NQIFAQRASEVYFVAAGLPLSLKGN
>Mature_185_residues
MKENKLILVLGGTRSGKSQYAEKIAKIQGQRVLYLATATVNDNEMKRRVRLHQERRPDAWDTREEPIKVTQVINELGDSY
DVILLDCLTLWITNLLLENQNINEAHLAEKEKQILQEASELALVCSKTNATVIVVSNEVGLSIVPEYPLGRVFRDISGLA
NQIFAQRASEVYFVAAGLPLSLKGN

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=39.2265193370166, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20717; Mature: 20717

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENKLILVLGGTRSGKSQYAEKIAKIQGQRVLYLATATVNDNEMKRRVRLHQERRPDAW
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCC
DTREEPIKVTQVINELGDSYDVILLDCLTLWITNLLLENQNINEAHLAEKEKQILQEASE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LALVCSKTNATVIVVSNEVGLSIVPEYPLGRVFRDISGLANQIFAQRASEVYFVAAGLPL
HEEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEE
SLKGN
EECCC
>Mature Secondary Structure
MKENKLILVLGGTRSGKSQYAEKIAKIQGQRVLYLATATVNDNEMKRRVRLHQERRPDAW
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCC
DTREEPIKVTQVINELGDSYDVILLDCLTLWITNLLLENQNINEAHLAEKEKQILQEASE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LALVCSKTNATVIVVSNEVGLSIVPEYPLGRVFRDISGLANQIFAQRASEVYFVAAGLPL
HEEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEE
SLKGN
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]