Click here to switch to the map view.

The map label for this gene is gpmB [H]

Identifier: 134299758

GI number: 134299758

Start: 2097661

End: 2098287

Strand: Reverse

Name: gpmB [H]

Synonym: Dred_1908

Alternate gene names: 134299758

Gene position: 2098287-2097661 (Counterclockwise)

Preceding gene: 134299760

Following gene: 134299757

Centisome position: 58.15

GC content: 40.99

Gene sequence:

>627_bases
ATGAAAAAAACCAGAATGTATTTGGTACGACATGGAGAAACCCAGTGGAATGCCGATGGCAGATTTCAAGGACATTCCGA
TGTACCGTTATCAGTTTTAGGCAGAAGCCAAGTGGAAACCCTAACGACTAAGTTAAGTCAGCTTAAAATTGACGCATTTT
ATAGCAGTGATTTATCAAGGGCTATGGAAACAGCAGAAATACTGGCAAAGAAACATCAATGTCAGATTTATTACCTGCCA
GATCTCCGAGAAATAAATTTTGGTGAATGGGAAGGTCTTACCTTTGAGGAAATAGCCCAAAACTATGGTGAACTTAGTTC
ACAATGGTGGGCTAACCCATTTACAACCCAAATACCCAGCGGTGAGAGTTTGCAGGATGTTGCAGAGCGCTGTGCAAAGG
CTGTGCACGAAATAATAGACCGTCATGCTGGTAAAACTGTGGTGGTAGCAGCTCATGGCGGTGTCATTCGTATGATTGTT
GCCCATGCTTTGGGGATGGATTTTCAGCATTATTGGAAACTACGTTTGGATAATGTATCATTAACCATTGTTGAGTACCA
TGGTTATGAAAAGGCGATTTTAGAATTGTATAACGATACTTGCCATTTAAAAAACACACCGTCTTAG

Upstream 100 bases:

>100_bases
TATCGAGAACCGGTTCTCATACATGGACTCCACCTTATTCCATTTATGGAAATTAGGTTTGTCCAGTGAATCTATTACTA
TTATACGAGGAGGGACGTCA

Downstream 100 bases:

>100_bases
GGCGGTTTTTATTTATTTAAATTATAAATTCTGGATAATAGTTACCCTACTGAGAAAAACTATTTTTAGCAATCGGTAGG
GAGGGAAATGAATATGGAAG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKTRMYLVRHGETQWNADGRFQGHSDVPLSVLGRSQVETLTTKLSQLKIDAFYSSDLSRAMETAEILAKKHQCQIYYLP
DLREINFGEWEGLTFEEIAQNYGELSSQWWANPFTTQIPSGESLQDVAERCAKAVHEIIDRHAGKTVVVAAHGGVIRMIV
AHALGMDFQHYWKLRLDNVSLTIVEYHGYEKAILELYNDTCHLKNTPS

Sequences:

>Translated_208_residues
MKKTRMYLVRHGETQWNADGRFQGHSDVPLSVLGRSQVETLTTKLSQLKIDAFYSSDLSRAMETAEILAKKHQCQIYYLP
DLREINFGEWEGLTFEEIAQNYGELSSQWWANPFTTQIPSGESLQDVAERCAKAVHEIIDRHAGKTVVVAAHGGVIRMIV
AHALGMDFQHYWKLRLDNVSLTIVEYHGYEKAILELYNDTCHLKNTPS
>Mature_208_residues
MKKTRMYLVRHGETQWNADGRFQGHSDVPLSVLGRSQVETLTTKLSQLKIDAFYSSDLSRAMETAEILAKKHQCQIYYLP
DLREINFGEWEGLTFEEIAQNYGELSSQWWANPFTTQIPSGESLQDVAERCAKAVHEIIDRHAGKTVVVAAHGGVIRMIV
AHALGMDFQHYWKLRLDNVSLTIVEYHGYEKAILELYNDTCHLKNTPS

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI64762445, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI64762406, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI118582286, Length=186, Percent_Identity=30.6451612903226, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI4758902, Length=187, Percent_Identity=31.0160427807487, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4758900, Length=186, Percent_Identity=31.1827956989247, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI224282149, Length=186, Percent_Identity=31.1827956989247, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4502445, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI40353764, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1790856, Length=183, Percent_Identity=35.5191256830601, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786857, Length=174, Percent_Identity=32.183908045977, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1786970, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25145314, Length=159, Percent_Identity=31.4465408805031, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17510917, Length=159, Percent_Identity=32.7044025157233, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993390, Length=159, Percent_Identity=32.7044025157233, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324857, Length=190, Percent_Identity=29.4736842105263, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322896, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648979, Length=222, Percent_Identity=28.8288288288288, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571817, Length=222, Percent_Identity=28.8288288288288, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571815, Length=222, Percent_Identity=28.8288288288288, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24643264, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643254, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643260, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643258, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643256, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643262, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643252, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137706, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23755; Mature: 23755

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTRMYLVRHGETQWNADGRFQGHSDVPLSVLGRSQVETLTTKLSQLKIDAFYSSDLSR
CCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMETAEILAKKHQCQIYYLPDLREINFGEWEGLTFEEIAQNYGELSSQWWANPFTTQIPS
HHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
GESLQDVAERCAKAVHEIIDRHAGKTVVVAAHGGVIRMIVAHALGMDFQHYWKLRLDNVS
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHEEEEECCEE
LTIVEYHGYEKAILELYNDTCHLKNTPS
EEEEEECCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKTRMYLVRHGETQWNADGRFQGHSDVPLSVLGRSQVETLTTKLSQLKIDAFYSSDLSR
CCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMETAEILAKKHQCQIYYLPDLREINFGEWEGLTFEEIAQNYGELSSQWWANPFTTQIPS
HHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
GESLQDVAERCAKAVHEIIDRHAGKTVVVAAHGGVIRMIVAHALGMDFQHYWKLRLDNVS
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHEEEEECCEE
LTIVEYHGYEKAILELYNDTCHLKNTPS
EEEEEECCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA