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The map label for this gene is nuoE [H]

Identifier: 134299711

GI number: 134299711

Start: 2041959

End: 2042441

Strand: Reverse

Name: nuoE [H]

Synonym: Dred_1858

Alternate gene names: 134299711

Gene position: 2042441-2041959 (Counterclockwise)

Preceding gene: 134299713

Following gene: 134299710

Centisome position: 56.61

GC content: 44.51

Gene sequence:

>483_bases
TTGTGTACAAGTTGTTGTAGTTTTAAAGACCCAAAACAAAAAGCATTAAAGGAGACCTTTGCCCGCTATCAGGGGACTTC
GGGTTCATTAATTCCGATACTACAGGAAGCCCAAGAAATATATGGTTACTTATCTGGTGAAGTGATGCAGCAGATAGCAC
GAGAGTTAAATATTCCCTATAGTAAGGTCTATGGAGTGGTTACTTTTTATGCCCAATTTCATCTTAGACCTCGGGGGCGA
AATATTATCCGTATTTGCACTGGTACAGCCTGTCATGTGAAGGGGGCAGACCGCTTGCTGGAAACCGTACGAGAGGCAAC
CGGTCTGGAAGGCGAAGGGACAACTGAAGACTTGCGCTACACACTGGAAACAGTAGCCTGTTTAGGTGCCTGTGGACTAG
CTCCCGCCATGATGATTAACGAAGATACTTACGGGCGCCTTACTCCGGTCAAAGCTTTAAATATTTTAAAACAGTATCAA
TAG

Upstream 100 bases:

>100_bases
AGCTGTTGTACTATGTCGATTTATTGATAAAATTAATTACTAAGTAAAACTCGTCCATACTAGTTTGCTTATCTTAGAAT
AATACCGGGGGGAGTATAGC

Downstream 100 bases:

>100_bases
ACAGAGGTGTCATGGTGAAAAACATTGATAATAATACTCCTAAAGTGGTTTGTATTTGCGCTGGTGGTTGCACTTCCTCC
GGTTCCTTGAAAATATTAGA

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MCTSCCSFKDPKQKALKETFARYQGTSGSLIPILQEAQEIYGYLSGEVMQQIARELNIPYSKVYGVVTFYAQFHLRPRGR
NIIRICTGTACHVKGADRLLETVREATGLEGEGTTEDLRYTLETVACLGACGLAPAMMINEDTYGRLTPVKALNILKQYQ

Sequences:

>Translated_160_residues
MCTSCCSFKDPKQKALKETFARYQGTSGSLIPILQEAQEIYGYLSGEVMQQIARELNIPYSKVYGVVTFYAQFHLRPRGR
NIIRICTGTACHVKGADRLLETVREATGLEGEGTTEDLRYTLETVACLGACGLAPAMMINEDTYGRLTPVKALNILKQYQ
>Mature_160_residues
MCTSCCSFKDPKQKALKETFARYQGTSGSLIPILQEAQEIYGYLSGEVMQQIARELNIPYSKVYGVVTFYAQFHLRPRGR
NIIRICTGTACHVKGADRLLETVREATGLEGEGTTEDLRYTLETVACLGACGLAPAMMINEDTYGRLTPVKALNILKQYQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=122, Percent_Identity=36.8852459016393, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1788621, Length=149, Percent_Identity=33.5570469798658, Blast_Score=98, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561328, Length=134, Percent_Identity=37.3134328358209, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859877, Length=133, Percent_Identity=39.8496240601504, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355353, Length=151, Percent_Identity=33.112582781457, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17782; Mature: 17782

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTSCCSFKDPKQKALKETFARYQGTSGSLIPILQEAQEIYGYLSGEVMQQIARELNIPY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SKVYGVVTFYAQFHLRPRGRNIIRICTGTACHVKGADRLLETVREATGLEGEGTTEDLRY
HHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHH
TLETVACLGACGLAPAMMINEDTYGRLTPVKALNILKQYQ
HHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MCTSCCSFKDPKQKALKETFARYQGTSGSLIPILQEAQEIYGYLSGEVMQQIARELNIPY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SKVYGVVTFYAQFHLRPRGRNIIRICTGTACHVKGADRLLETVREATGLEGEGTTEDLRY
HHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHH
TLETVACLGACGLAPAMMINEDTYGRLTPVKALNILKQYQ
HHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA