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The map label for this gene is nuoG [C]

Identifier: 134299508

GI number: 134299508

Start: 1805753

End: 1807534

Strand: Reverse

Name: nuoG [C]

Synonym: Dred_1651

Alternate gene names: 134299508

Gene position: 1807534-1805753 (Counterclockwise)

Preceding gene: 134299509

Following gene: 134299506

Centisome position: 50.1

GC content: 46.52

Gene sequence:

>1782_bases
ATGGCAACTGTAACACTAACCATTGACAATGTAAAAGTTGAAGTTGAACAAGGTTCAACGATATTAGATGCTGCGAAAAA
AATTGGCATTAATATTCCAACCCTTTGCTATATGAAAGAGATTAATGCCATTGGCGCCTGTCGTATTTGCGTGGTAGAAG
TAGTAGGTGCCCGGGCCCTCCAGGCTGCCTGTGTTACCCCAGCTACGGAAGGCATGGTTGTAAAGACCAACTCAGCAGCC
GTTAGAGCTTCCCGCAAAATGACTCTTGAACTGATTCAGTCTAATCACCCGCAGGAATGCAACACCTGCCTGCGTAACAA
CAATTGTGAACTGCAAGCTCTTTCCGAAGCCATGGGACTTAAAGAGGTTCGTTTTATAAGACCTTCCCAAAGCCATAGTA
AAGACGATATCGACAACTCTTCCCCATCCATCGTTCGTGACCCTCGGAAGTGTATTTTGTGCCGTCGTTGTGTAGCAGTT
TGCGAAAAGGTACAAGGCGTTAAGTGTATCAGTGCTGTAAACCGTGGCTTTGAAACCACCATTGCACCTCCATTTAACCA
AGGTCTGTTTGATGTAAACTGCACCATGTGCGGTCAGTGCACCCTAGTCTGCCCCACTGGTGCCATCACTGAAGTGGATG
ACACTGGTAAAGTATGGCGCGCTCTGGATGATTCAACCAAACACGTGGTTGTTCAAACTGCACCCGCAGTACGCGTAGCC
ATTGCTGAAGAATTTGGTATGGAACCAGGCACTGTTAGTACCGGCAAACTGGTTGCAGCTCTACGTCGCCTCGGCTTTGA
TAGCGTCATGGATACCGACTTTGCAGCTGACTTAACCATTTTAGAAGAGGGTAATGAATTTATTAAGCGGGTCACCGAAG
GTGGCGTACTGCCGATGATCACTTCCTGCAGTCCTGGTTGGATTAAATACATTGAAATGTATTATCCCGACCTGTTGGCT
CACCTTTCCACTTGTAAGTCCCCTCAACAAATGTTTGGAGCACTGGTTAAGTCCTTCTATGCTGAGAAAAAAGCAATTGA
TCCAGCCAATATCGTCAGTGTATCGATCATGCCTTGTACAGCTAAGAAGTTTGAAGCCCAGCGTGATGAACTTAGGGACA
GTGGTTATCAGGATGTGGACATTGTTCTTACCACCCGCGAACTTGCACGTATGCTCCGAGAAATTGGCATTGATTGGGAT
AATCTTTCCGATGACGATTACGATGCCCCAATGGGCTTATCCACTGGTGCTGCGGTTATCTTCGGTGTTACCGGCGGTGT
AATGGAAGCAGCTGTACGTACTGTATACGAAGTACTTACCAAGGAAGCCATGCCAAATATTAACTTAACCCCAGTACGTG
GCATGGAAGGTATTAAAGAAGCTACCCTTAAGGTTGGAGACCTAGATGTAAAAGTAGCAGTTGCTCATACCCTGGGTAAT
GCCCGTAAACTTTTAGATAAAATCCGTGCCGGCGAAGCCGATTATCACTTTATCGAAATAATGTGCTGCCCTGGTGGTTG
TATTGGCGGCGGTGGTCAACCTATTCCTACGAACCTAGAAGTACGCCTTAAACGTATTGCCGGCACCTATAGGGCTGATG
AAGCTTTGCCACTTCGTAAATCCCATGAAAACCCTGCCATCAAGGCAATTTATGAAGAATTCTTGGGAGAACCCCTGGGA
GAGAAGTCACATAAACTTCTTCATACCCACTATGTGCCCCGTGGCGTTTATAGGAAACCAGAAGGCCTACCGAATAAAGT
ACCCTCAGGAGAACATCATTAG

Upstream 100 bases:

>100_bases
GATGAATTTGAAGCCCACATTAAGGATAAAACCTGCCCGGCTGGCGTTTGCAAAATGCCCCGCAAAGGCCTAAAATCCTA
GAGGATAGGAGGGAAAAGGC

Downstream 100 bases:

>100_bases
ATTATATTTTGTTTTTATTAACCCGACGCAAAGTCGGGTTAATCTTTTCTTATATAGCTATTATATGCAATTTATATGCC
ACAATATAAAGCTAAGTATT

Product: hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MATVTLTIDNVKVEVEQGSTILDAAKKIGINIPTLCYMKEINAIGACRICVVEVVGARALQAACVTPATEGMVVKTNSAA
VRASRKMTLELIQSNHPQECNTCLRNNNCELQALSEAMGLKEVRFIRPSQSHSKDDIDNSSPSIVRDPRKCILCRRCVAV
CEKVQGVKCISAVNRGFETTIAPPFNQGLFDVNCTMCGQCTLVCPTGAITEVDDTGKVWRALDDSTKHVVVQTAPAVRVA
IAEEFGMEPGTVSTGKLVAALRRLGFDSVMDTDFAADLTILEEGNEFIKRVTEGGVLPMITSCSPGWIKYIEMYYPDLLA
HLSTCKSPQQMFGALVKSFYAEKKAIDPANIVSVSIMPCTAKKFEAQRDELRDSGYQDVDIVLTTRELARMLREIGIDWD
NLSDDDYDAPMGLSTGAAVIFGVTGGVMEAAVRTVYEVLTKEAMPNINLTPVRGMEGIKEATLKVGDLDVKVAVAHTLGN
ARKLLDKIRAGEADYHFIEIMCCPGGCIGGGGQPIPTNLEVRLKRIAGTYRADEALPLRKSHENPAIKAIYEEFLGEPLG
EKSHKLLHTHYVPRGVYRKPEGLPNKVPSGEHH

Sequences:

>Translated_593_residues
MATVTLTIDNVKVEVEQGSTILDAAKKIGINIPTLCYMKEINAIGACRICVVEVVGARALQAACVTPATEGMVVKTNSAA
VRASRKMTLELIQSNHPQECNTCLRNNNCELQALSEAMGLKEVRFIRPSQSHSKDDIDNSSPSIVRDPRKCILCRRCVAV
CEKVQGVKCISAVNRGFETTIAPPFNQGLFDVNCTMCGQCTLVCPTGAITEVDDTGKVWRALDDSTKHVVVQTAPAVRVA
IAEEFGMEPGTVSTGKLVAALRRLGFDSVMDTDFAADLTILEEGNEFIKRVTEGGVLPMITSCSPGWIKYIEMYYPDLLA
HLSTCKSPQQMFGALVKSFYAEKKAIDPANIVSVSIMPCTAKKFEAQRDELRDSGYQDVDIVLTTRELARMLREIGIDWD
NLSDDDYDAPMGLSTGAAVIFGVTGGVMEAAVRTVYEVLTKEAMPNINLTPVRGMEGIKEATLKVGDLDVKVAVAHTLGN
ARKLLDKIRAGEADYHFIEIMCCPGGCIGGGGQPIPTNLEVRLKRIAGTYRADEALPLRKSHENPAIKAIYEEFLGEPLG
EKSHKLLHTHYVPRGVYRKPEGLPNKVPSGEHH
>Mature_592_residues
ATVTLTIDNVKVEVEQGSTILDAAKKIGINIPTLCYMKEINAIGACRICVVEVVGARALQAACVTPATEGMVVKTNSAAV
RASRKMTLELIQSNHPQECNTCLRNNNCELQALSEAMGLKEVRFIRPSQSHSKDDIDNSSPSIVRDPRKCILCRRCVAVC
EKVQGVKCISAVNRGFETTIAPPFNQGLFDVNCTMCGQCTLVCPTGAITEVDDTGKVWRALDDSTKHVVVQTAPAVRVAI
AEEFGMEPGTVSTGKLVAALRRLGFDSVMDTDFAADLTILEEGNEFIKRVTEGGVLPMITSCSPGWIKYIEMYYPDLLAH
LSTCKSPQQMFGALVKSFYAEKKAIDPANIVSVSIMPCTAKKFEAQRDELRDSGYQDVDIVLTTRELARMLREIGIDWDN
LSDDDYDAPMGLSTGAAVIFGVTGGVMEAAVRTVYEVLTKEAMPNINLTPVRGMEGIKEATLKVGDLDVKVAVAHTLGNA
RKLLDKIRAGEADYHFIEIMCCPGGCIGGGGQPIPTNLEVRLKRIAGTYRADEALPLRKSHENPAIKAIYEEFLGEPLGE
KSHKLLHTHYVPRGVYRKPEGLPNKVPSGEHH

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=406, Percent_Identity=31.5270935960591, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI6912524, Length=410, Percent_Identity=29.5121951219512, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI134284357, Length=370, Percent_Identity=30.8108108108108, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI84452151, Length=370, Percent_Identity=30.8108108108108, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI14165461, Length=449, Percent_Identity=28.7305122494432, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI33519475, Length=207, Percent_Identity=29.4685990338164, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI145693161, Length=239, Percent_Identity=25.1046025104602, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995015, Length=400, Percent_Identity=29, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17565758, Length=209, Percent_Identity=32.5358851674641, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566231, Length=209, Percent_Identity=32.5358851674641, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193209088, Length=247, Percent_Identity=30.3643724696356, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324089, Length=342, Percent_Identity=24.5614035087719, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007470, Length=352, Percent_Identity=31.5340909090909, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI116007466, Length=352, Percent_Identity=31.5340909090909, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI116007464, Length=352, Percent_Identity=31.5340909090909, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI116007468, Length=352, Percent_Identity=31.5340909090909, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI116007462, Length=286, Percent_Identity=31.4685314685315, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24640559, Length=209, Percent_Identity=32.5358851674641, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24640557, Length=209, Percent_Identity=32.5358851674641, Blast_Score=117, Evalue=3e-26,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 64559; Mature: 64428

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVTLTIDNVKVEVEQGSTILDAAKKIGINIPTLCYMKEINAIGACRICVVEVVGARAL
CEEEEEEEECEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
QAACVTPATEGMVVKTNSAAVRASRKMTLELIQSNHPQECNTCLRNNNCELQALSEAMGL
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCC
KEVRFIRPSQSHSKDDIDNSSPSIVRDPRKCILCRRCVAVCEKVQGVKCISAVNRGFETT
HHEEEECCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
IAPPFNQGLFDVNCTMCGQCTLVCPTGAITEVDDTGKVWRALDDSTKHVVVQTAPAVRVA
CCCCCCCCEEEECCEEECCEEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEE
IAEEFGMEPGTVSTGKLVAALRRLGFDSVMDTDFAADLTILEEGNEFIKRVTEGGVLPMI
EHHHHCCCCCCCCHHHHHHHHHHCCCHHHHCCCHHCCEEEECCCHHHHHHHHCCCCEEEE
TSCSPGWIKYIEMYYPDLLAHLSTCKSPQQMFGALVKSFYAEKKAIDPANIVSVSIMPCT
ECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
AKKFEAQRDELRDSGYQDVDIVLTTRELARMLREIGIDWDNLSDDDYDAPMGLSTGAAVI
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
FGVTGGVMEAAVRTVYEVLTKEAMPNINLTPVRGMEGIKEATLKVGDLDVKVAVAHTLGN
EECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCEEEEEEHHHHHH
ARKLLDKIRAGEADYHFIEIMCCPGGCIGGGGQPIPTNLEVRLKRIAGTYRADEALPLRK
HHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SHENPAIKAIYEEFLGEPLGEKSHKLLHTHYVPRGVYRKPEGLPNKVPSGEHH
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATVTLTIDNVKVEVEQGSTILDAAKKIGINIPTLCYMKEINAIGACRICVVEVVGARAL
EEEEEEEECEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
QAACVTPATEGMVVKTNSAAVRASRKMTLELIQSNHPQECNTCLRNNNCELQALSEAMGL
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCC
KEVRFIRPSQSHSKDDIDNSSPSIVRDPRKCILCRRCVAVCEKVQGVKCISAVNRGFETT
HHEEEECCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
IAPPFNQGLFDVNCTMCGQCTLVCPTGAITEVDDTGKVWRALDDSTKHVVVQTAPAVRVA
CCCCCCCCEEEECCEEECCEEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEE
IAEEFGMEPGTVSTGKLVAALRRLGFDSVMDTDFAADLTILEEGNEFIKRVTEGGVLPMI
EHHHHCCCCCCCCHHHHHHHHHHCCCHHHHCCCHHCCEEEECCCHHHHHHHHCCCCEEEE
TSCSPGWIKYIEMYYPDLLAHLSTCKSPQQMFGALVKSFYAEKKAIDPANIVSVSIMPCT
ECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
AKKFEAQRDELRDSGYQDVDIVLTTRELARMLREIGIDWDNLSDDDYDAPMGLSTGAAVI
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
FGVTGGVMEAAVRTVYEVLTKEAMPNINLTPVRGMEGIKEATLKVGDLDVKVAVAHTLGN
EECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEECCCEEEEEEHHHHHH
ARKLLDKIRAGEADYHFIEIMCCPGGCIGGGGQPIPTNLEVRLKRIAGTYRADEALPLRK
HHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SHENPAIKAIYEEFLGEPLGEKSHKLLHTHYVPRGVYRKPEGLPNKVPSGEHH
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]