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The map label for this gene is coaE [H]

Identifier: 134299453

GI number: 134299453

Start: 1735706

End: 1736311

Strand: Reverse

Name: coaE [H]

Synonym: Dred_1596

Alternate gene names: 134299453

Gene position: 1736311-1735706 (Counterclockwise)

Preceding gene: 134299454

Following gene: 134299452

Centisome position: 48.12

GC content: 41.58

Gene sequence:

>606_bases
ATGATTATTGGGTTAACCGGTAACATTGCCAGCGGCAAGAGTACCGTGTCGCACTTATTAAAGGAGTTAGGAGCTAAGGT
GATTGATACGGACCGGGTAGCTCGGGAAATTGTATTGCCTGATACACCTGCCCTAAAGGAGATTGTTTTCTCCTTTGGGG
CAGGTGTTCTAAACAACGATGGAACATTGAATCGAGCCAAATTGGCAACCATTGTATTTGACAACCCGGCGGCTAGAAGG
AAATTAGAGGCCATTACACACCCCCGCATCGAAGAAGAAATTAACCAACAAATTGAGTTTTTTTCCAAGGATAATCATGC
TTCGGTTCTTGTGCTGGAAGTTCCCCTGCTGATTGAAGTGGGTTGGCATAAAAAGGTCGATCAGGTATGGTTGGTAACGG
TTGATGAACGGGTTCAGTTAGAACGTTTAATGCAAAGGGACAAGCTTTCCCCAGAACAAGCTAAAAAACGTATCCACAGC
CAAATGCCACAAAGGGAAAAAATGAAATATGCCAATGTTATCATTGATAATTCCGGTACTCCCGAGGAAGTAAAGCAAAA
ATTAATAGTTATTTGGTCCAACTTAATAAATTATTTACATGATTAA

Upstream 100 bases:

>100_bases
TTGGGTCGGCAATTGGCATTGGTTCCAGGGTGTATTCTCATCCTGTTGGGGCTTTTTAAAATTAAGTAATTAACTTTTTA
CTTTCTAAGGAGTGTGTTTT

Downstream 100 bases:

>100_bases
CCATTTTCTGGTATATAATGTATTGGTTAAGTTTGTTTGCAGGAGTGATGACAGTGACTATTCGAAGCAAAAAAAATAGA
GGCTTTAAAAGAAGGCTCCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIIGLTGNIASGKSTVSHLLKELGAKVIDTDRVAREIVLPDTPALKEIVFSFGAGVLNNDGTLNRAKLATIVFDNPAARR
KLEAITHPRIEEEINQQIEFFSKDNHASVLVLEVPLLIEVGWHKKVDQVWLVTVDERVQLERLMQRDKLSPEQAKKRIHS
QMPQREKMKYANVIIDNSGTPEEVKQKLIVIWSNLINYLHD

Sequences:

>Translated_201_residues
MIIGLTGNIASGKSTVSHLLKELGAKVIDTDRVAREIVLPDTPALKEIVFSFGAGVLNNDGTLNRAKLATIVFDNPAARR
KLEAITHPRIEEEINQQIEFFSKDNHASVLVLEVPLLIEVGWHKKVDQVWLVTVDERVQLERLMQRDKLSPEQAKKRIHS
QMPQREKMKYANVIIDNSGTPEEVKQKLIVIWSNLINYLHD
>Mature_201_residues
MIIGLTGNIASGKSTVSHLLKELGAKVIDTDRVAREIVLPDTPALKEIVFSFGAGVLNNDGTLNRAKLATIVFDNPAARR
KLEAITHPRIEEEINQQIEFFSKDNHASVLVLEVPLLIEVGWHKKVDQVWLVTVDERVQLERLMQRDKLSPEQAKKRIHS
QMPQREKMKYANVIIDNSGTPEEVKQKLIVIWSNLINYLHD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=197, Percent_Identity=37.5634517766497, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI191252795, Length=197, Percent_Identity=37.5634517766497, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI110227607, Length=194, Percent_Identity=31.4432989690722, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI110227605, Length=194, Percent_Identity=31.4432989690722, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI110227603, Length=194, Percent_Identity=31.4432989690722, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI110227601, Length=194, Percent_Identity=31.4432989690722, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI205277394, Length=194, Percent_Identity=31.4432989690722, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1786292, Length=183, Percent_Identity=38.2513661202186, Blast_Score=121, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=36.3157894736842, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=175, Percent_Identity=34.8571428571429, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=189, Percent_Identity=37.5661375661376, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644728, Length=210, Percent_Identity=38.0952380952381, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24658602, Length=199, Percent_Identity=34.6733668341709, Blast_Score=123, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22788; Mature: 22788

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLTGNIASGKSTVSHLLKELGAKVIDTDRVAREIVLPDTPALKEIVFSFGAGVLNND
CEEEECCCCCCCHHHHHHHHHHHCCHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
GTLNRAKLATIVFDNPAARRKLEAITHPRIEEEINQQIEFFSKDNHASVLVLEVPLLIEV
CCCCHHEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECEEEEE
GWHKKVDQVWLVTVDERVQLERLMQRDKLSPEQAKKRIHSQMPQREKMKYANVIIDNSGT
CCCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHEEECCCCC
PEEVKQKLIVIWSNLINYLHD
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIGLTGNIASGKSTVSHLLKELGAKVIDTDRVAREIVLPDTPALKEIVFSFGAGVLNND
CEEEECCCCCCCHHHHHHHHHHHCCHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
GTLNRAKLATIVFDNPAARRKLEAITHPRIEEEINQQIEFFSKDNHASVLVLEVPLLIEV
CCCCHHEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECEEEEE
GWHKKVDQVWLVTVDERVQLERLMQRDKLSPEQAKKRIHSQMPQREKMKYANVIIDNSGT
CCCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHEEECCCCC
PEEVKQKLIVIWSNLINYLHD
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA