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The map label for this gene is mltD [C]

Identifier: 134299272

GI number: 134299272

Start: 1528564

End: 1529535

Strand: Reverse

Name: mltD [C]

Synonym: Dred_1413

Alternate gene names: 134299272

Gene position: 1529535-1528564 (Counterclockwise)

Preceding gene: 134299277

Following gene: 134299266

Centisome position: 42.39

GC content: 42.28

Gene sequence:

>972_bases
ATGTCAAAAAGTAAACTTATTTTACCAGGATTACTAATTTCACTTTTGTTAAGTGCCAACCCAGTCCTAGCGGCTGATTA
TACCGTAAAAGATGGTGATTCCCTTTGGAAAATATCTCAAAAAAATAATATCAGCATTGATAAATTAAAGGCGATCAATG
GTTTGAGCAATGACCTTCTTTCTGTGGGACAAGTTCTTCGTATTGATGGAACCCCTGAGACAAAGCAGGCATCAACCGCT
AAACAACAGCCCATGCCTCAGACCACAAAAACTAACCAAACTGGTTGGCTTCCTACGAATACCTCATTAGAGAGTCAGGA
AAAACAGCCAAATACTGTGGCCTCTTATCGTCCCAACAATACGCTGTATACTGTGAAACCAGGGGATACCCTGGGTGCCA
TAGCGCAAAAGAACGGAATTAGTCTTGAAGATTTACGCGGGCTTAATAACCTGAAGGGTGATTTAATCTATGCCGGGCAA
ACCTTGGTTTTAAAGGGTAGTGTTTCCCGAGGCGGGGATGTGCATCGTTCTGATTCCATAGATGAGAACTCCTCTGTACG
TTATGGCCAATTAGTTGATTGGTTCACTGAGGGAATTAATATTCTGAAACCCAATAAAGTCTTTACCGTAACCGATACGG
CAACAGGAAAAATCATCAAACTTCAAGTGCTGGGGGGAAGCAACCACTGTGATGTGGAACCCTTAACAAAAGAAGACACT
GAAACAATGTTAAGCCTCTTTACTGCTTGGACTTGGACCCCCAGACCTGTTTGTATTCATATAGATGGAAGAGATATTGC
CGCCTCCCTCTCTGGCATGCCCCATACAACCATTGAAAATATAAAGGATAATAATGTTACCGGGCATTATGATATGTATC
TGCTAAATAGCAAACCCCACGGTAGCGGTGTATCTCAAAGCTATGTTCAGCAGCATTACGATGCTCTGGAAAGAGCAGCA
AAAGTCGATTAG

Upstream 100 bases:

>100_bases
AACAAGTTTTTATGGTTAAAATGGTAGCAATGGATATTTATGGATTGTTATGTAGAAACAGATGCCTCAACAACTAAAAT
TTACACAAAGGGGTAGCTAA

Downstream 100 bases:

>100_bases
TGTAACACCGTAGTAAACGTCGTTAGCCTCCGGCTAGAAGGGCTGCGCAATTCGCAGCCCATACCCCACAGAACCAGCTG
TTCAGATTTACCGCAACTAG

Product: peptidoglycan-binding LysM

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: Beta-glycosidase; Peptidoglycan hydrolase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSKSKLILPGLLISLLLSANPVLAADYTVKDGDSLWKISQKNNISIDKLKAINGLSNDLLSVGQVLRIDGTPETKQASTA
KQQPMPQTTKTNQTGWLPTNTSLESQEKQPNTVASYRPNNTLYTVKPGDTLGAIAQKNGISLEDLRGLNNLKGDLIYAGQ
TLVLKGSVSRGGDVHRSDSIDENSSVRYGQLVDWFTEGINILKPNKVFTVTDTATGKIIKLQVLGGSNHCDVEPLTKEDT
ETMLSLFTAWTWTPRPVCIHIDGRDIAASLSGMPHTTIENIKDNNVTGHYDMYLLNSKPHGSGVSQSYVQQHYDALERAA
KVD

Sequences:

>Translated_323_residues
MSKSKLILPGLLISLLLSANPVLAADYTVKDGDSLWKISQKNNISIDKLKAINGLSNDLLSVGQVLRIDGTPETKQASTA
KQQPMPQTTKTNQTGWLPTNTSLESQEKQPNTVASYRPNNTLYTVKPGDTLGAIAQKNGISLEDLRGLNNLKGDLIYAGQ
TLVLKGSVSRGGDVHRSDSIDENSSVRYGQLVDWFTEGINILKPNKVFTVTDTATGKIIKLQVLGGSNHCDVEPLTKEDT
ETMLSLFTAWTWTPRPVCIHIDGRDIAASLSGMPHTTIENIKDNNVTGHYDMYLLNSKPHGSGVSQSYVQQHYDALERAA
KVD
>Mature_322_residues
SKSKLILPGLLISLLLSANPVLAADYTVKDGDSLWKISQKNNISIDKLKAINGLSNDLLSVGQVLRIDGTPETKQASTAK
QQPMPQTTKTNQTGWLPTNTSLESQEKQPNTVASYRPNNTLYTVKPGDTLGAIAQKNGISLEDLRGLNNLKGDLIYAGQT
LVLKGSVSRGGDVHRSDSIDENSSVRYGQLVDWFTEGINILKPNKVFTVTDTATGKIIKLQVLGGSNHCDVEPLTKEDTE
TMLSLFTAWTWTPRPVCIHIDGRDIAASLSGMPHTTIENIKDNNVTGHYDMYLLNSKPHGSGVSQSYVQQHYDALERAAK
VD

Specific function: Hydrolyzes the cell wall of E.faecalis and M.lysodeikticus. May play an important role in cell wall growth and cell separation [H]

COG id: COG1388

COG function: function code M; FOG: LysM repeat

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 LysM repeats [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013338
- InterPro:   IPR002901
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01832 Glucosaminidase; PF01476 LysM [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 35215; Mature: 35084

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKLILPGLLISLLLSANPVLAADYTVKDGDSLWKISQKNNISIDKLKAINGLSNDLL
CCCCCEEHHHHHHHHHHCCCCEEEECEEECCCCCEEEECCCCCCCHHHHHHHCCCHHHHH
SVGQVLRIDGTPETKQASTAKQQPMPQTTKTNQTGWLPTNTSLESQEKQPNTVASYRPNN
HCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
TLYTVKPGDTLGAIAQKNGISLEDLRGLNNLKGDLIYAGQTLVLKGSVSRGGDVHRSDSI
EEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCC
DENSSVRYGQLVDWFTEGINILKPNKVFTVTDTATGKIIKLQVLGGSNHCDVEPLTKEDT
CCCCCCCHHHHHHHHHCCCEEECCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCHHH
ETMLSLFTAWTWTPRPVCIHIDGRDIAASLSGMPHTTIENIKDNNVTGHYDMYLLNSKPH
HHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEECCCCC
GSGVSQSYVQQHYDALERAAKVD
CCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKSKLILPGLLISLLLSANPVLAADYTVKDGDSLWKISQKNNISIDKLKAINGLSNDLL
CCCCEEHHHHHHHHHHCCCCEEEECEEECCCCCEEEECCCCCCCHHHHHHHCCCHHHHH
SVGQVLRIDGTPETKQASTAKQQPMPQTTKTNQTGWLPTNTSLESQEKQPNTVASYRPNN
HCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
TLYTVKPGDTLGAIAQKNGISLEDLRGLNNLKGDLIYAGQTLVLKGSVSRGGDVHRSDSI
EEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCC
DENSSVRYGQLVDWFTEGINILKPNKVFTVTDTATGKIIKLQVLGGSNHCDVEPLTKEDT
CCCCCCCHHHHHHHHHCCCEEECCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCHHH
ETMLSLFTAWTWTPRPVCIHIDGRDIAASLSGMPHTTIENIKDNNVTGHYDMYLLNSKPH
HHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEECCCCC
GSGVSQSYVQQHYDALERAAKVD
CCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1679432; 12663927 [H]