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The map label for this gene is trpB [H]

Identifier: 134299223

GI number: 134299223

Start: 1461346

End: 1462521

Strand: Reverse

Name: trpB [H]

Synonym: Dred_1361

Alternate gene names: 134299223

Gene position: 1462521-1461346 (Counterclockwise)

Preceding gene: 134299226

Following gene: 134299221

Centisome position: 40.53

GC content: 42.26

Gene sequence:

>1176_bases
ATGAGTAATTTAACAGGCTTCTACGGAGAATTTGGGGGGGCCTTTGTCCCGGATTCACTTAGAAAAGTATTGGGTGATCT
TGAAGTAGCTTTTATGCGCTATAAGGATGACCCTGATTTTATTTCCGAACTTACTTATTATCTGCAACAATATGTTGGGC
GACCTAACCCGCTTTATTTTGCAGAAAGACTGACCAAAAAACTGGGCGGAGCCAAAATTTACCTTAAAAGAGAAGATCTT
AACCATACTGGCTCACACAAGATCAACAATGTACTTGGTCAGGTTTTACTGGCCAAAAGAATGGGCATTAAAAGAGTTAT
CGCCGAAACCGGGGCTGGTCAGCACGGAGTAGCCACGGCTACGGCCTGTGCTATGTTTAATATGGAATGTGTTATTTATA
TGGGTGAAGAAGATACCAAGCGTCAGGCACTAAATGTTTTTCGTATGGAATTGCTAGGTGCTAAAGTAGTAACAGTAACT
ACAGGCACAAAAACCCTTAAAGATGCTGTTGATGTGGCTTTACAAGATCTGGTAGAGAACCACGAAAATACTTATTATAT
GTTAGGTTCTGCCGTAGGTCCCCATCCTTACCCTCTAATTGTTCGACATTTTCAGTCGATAATTGGCATAGAAGCGAAGG
ACCAACTTCGAAAAATTGAAGGACGCTTACCGGACTATATAATGGCCTGTGTTGGCGGCGGTAGTAATGCCATTGGTTTG
TTTTATCCCTTTGTGGAGGATAAAGAAGTTAATATTATTGGCGTAGAACCAGGCGGTAAAGGTCTGGCAACAGGTCAACA
TGCCGCACCCTTATGTGCAGGAAAACCAGGAATTTTACATGGCTTTAAATGCTACTTAATGCAGGATGAAAATGGGGAAC
CATTAACAACGCATTCAATATCCGCTGGATTAGATTACCCTGGTGTTGGGCCGGAACACAGTTATTTAAAGGCTACGGGC
AGGGCCGAGTATGTAGCCATTAATGACACCGAAGCATTAGATGCCTTTAAAGAATTATCTAAAACAGAGGGTATTATACC
GGCACTTGAAAGTGCCCATGCTGTGGCCCATGCCATTAAAATCGCTCCTACCCTGCAACAAGATCAAATTATCATCGTTA
ACATCTCCGGACGTGGGGATAAGGATGTGGAGCAAGTTTTTTACATGTTAAAATAA

Upstream 100 bases:

>100_bases
ATAAAAAAATGATTGTATAGAATTATTATACATGTTAAAATAACACTAGTTTGATTTTTGTTTAGCTGAGCTTAGTTTTT
AAATTAGAGGAGGAGAAGAG

Downstream 100 bases:

>100_bases
AATTGAAAAAGTTTACTAAACCGACCTTTTTGTAGGTCGGTTTTTTGCTTATAAGAAAGTTTCTCATATCCTGCTGGTAT
GGCAGAAGCCAGTTGTCTAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSNLTGFYGEFGGAFVPDSLRKVLGDLEVAFMRYKDDPDFISELTYYLQQYVGRPNPLYFAERLTKKLGGAKIYLKREDL
NHTGSHKINNVLGQVLLAKRMGIKRVIAETGAGQHGVATATACAMFNMECVIYMGEEDTKRQALNVFRMELLGAKVVTVT
TGTKTLKDAVDVALQDLVENHENTYYMLGSAVGPHPYPLIVRHFQSIIGIEAKDQLRKIEGRLPDYIMACVGGGSNAIGL
FYPFVEDKEVNIIGVEPGGKGLATGQHAAPLCAGKPGILHGFKCYLMQDENGEPLTTHSISAGLDYPGVGPEHSYLKATG
RAEYVAINDTEALDAFKELSKTEGIIPALESAHAVAHAIKIAPTLQQDQIIIVNISGRGDKDVEQVFYMLK

Sequences:

>Translated_391_residues
MSNLTGFYGEFGGAFVPDSLRKVLGDLEVAFMRYKDDPDFISELTYYLQQYVGRPNPLYFAERLTKKLGGAKIYLKREDL
NHTGSHKINNVLGQVLLAKRMGIKRVIAETGAGQHGVATATACAMFNMECVIYMGEEDTKRQALNVFRMELLGAKVVTVT
TGTKTLKDAVDVALQDLVENHENTYYMLGSAVGPHPYPLIVRHFQSIIGIEAKDQLRKIEGRLPDYIMACVGGGSNAIGL
FYPFVEDKEVNIIGVEPGGKGLATGQHAAPLCAGKPGILHGFKCYLMQDENGEPLTTHSISAGLDYPGVGPEHSYLKATG
RAEYVAINDTEALDAFKELSKTEGIIPALESAHAVAHAIKIAPTLQQDQIIIVNISGRGDKDVEQVFYMLK
>Mature_390_residues
SNLTGFYGEFGGAFVPDSLRKVLGDLEVAFMRYKDDPDFISELTYYLQQYVGRPNPLYFAERLTKKLGGAKIYLKREDLN
HTGSHKINNVLGQVLLAKRMGIKRVIAETGAGQHGVATATACAMFNMECVIYMGEEDTKRQALNVFRMELLGAKVVTVTT
GTKTLKDAVDVALQDLVENHENTYYMLGSAVGPHPYPLIVRHFQSIIGIEAKDQLRKIEGRLPDYIMACVGGGSNAIGLF
YPFVEDKEVNIIGVEPGGKGLATGQHAAPLCAGKPGILHGFKCYLMQDENGEPLTTHSISAGLDYPGVGPEHSYLKATGR
AEYVAINDTEALDAFKELSKTEGIIPALESAHAVAHAIKIAPTLQQDQIIIVNISGRGDKDVEQVFYMLK

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=54.2416452442159, Blast_Score=427, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=58.3333333333333, Blast_Score=466, Evalue=1e-132,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42700; Mature: 42568

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLTGFYGEFGGAFVPDSLRKVLGDLEVAFMRYKDDPDFISELTYYLQQYVGRPNPLYF
CCCCCCCHHCCCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHH
AERLTKKLGGAKIYLKREDLNHTGSHKINNVLGQVLLAKRMGIKRVIAETGAGQHGVATA
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TACAMFNMECVIYMGEEDTKRQALNVFRMELLGAKVVTVTTGTKTLKDAVDVALQDLVEN
HHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHC
HENTYYMLGSAVGPHPYPLIVRHFQSIIGIEAKDQLRKIEGRLPDYIMACVGGGSNAIGL
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEE
FYPFVEDKEVNIIGVEPGGKGLATGQHAAPLCAGKPGILHGFKCYLMQDENGEPLTTHSI
EEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEE
SAGLDYPGVGPEHSYLKATGRAEYVAINDTEALDAFKELSKTEGIIPALESAHAVAHAIK
ECCCCCCCCCCCCHHEEECCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IAPTLQQDQIIIVNISGRGDKDVEQVFYMLK
HCCCCCCCCEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SNLTGFYGEFGGAFVPDSLRKVLGDLEVAFMRYKDDPDFISELTYYLQQYVGRPNPLYF
CCCCCCHHCCCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHH
AERLTKKLGGAKIYLKREDLNHTGSHKINNVLGQVLLAKRMGIKRVIAETGAGQHGVATA
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TACAMFNMECVIYMGEEDTKRQALNVFRMELLGAKVVTVTTGTKTLKDAVDVALQDLVEN
HHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHC
HENTYYMLGSAVGPHPYPLIVRHFQSIIGIEAKDQLRKIEGRLPDYIMACVGGGSNAIGL
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEE
FYPFVEDKEVNIIGVEPGGKGLATGQHAAPLCAGKPGILHGFKCYLMQDENGEPLTTHSI
EEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEE
SAGLDYPGVGPEHSYLKATGRAEYVAINDTEALDAFKELSKTEGIIPALESAHAVAHAIK
ECCCCCCCCCCCCHHEEECCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IAPTLQQDQIIIVNISGRGDKDVEQVFYMLK
HCCCCCCCCEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA