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The map label for this gene is intR [C]

Identifier: 134298368

GI number: 134298368

Start: 535138

End: 536289

Strand: Reverse

Name: intR [C]

Synonym: Dred_0493

Alternate gene names: 134298368

Gene position: 536289-535138 (Counterclockwise)

Preceding gene: 134298369

Following gene: 134298367

Centisome position: 14.86

GC content: 45.75

Gene sequence:

>1152_bases
ATGCCCGGCCATTTAGAAAAGCGGCACAAGAGTTCTTGGACAATTATTATTGACCTGGGGAAAGACCCCATAACCAACAA
ACGGAAGCGAATGGTGAGAGGTTTTAAGGGTACAAAGAAAGAAGCAGAAAAGGAAATGGCCCGCCTCATAGCCGAATATG
AGACAGGCCAGTATATCGAACCATCTAAAACCTGTTTGGGTGATTATATGCTACGCTGGCTAGAAGACTACGGCAAACCA
AATCTGGCACCTACCACCTACTACTCTTACAGCAAAATAGTCGAAAAGCACATCATACCATCCATCGGGTCCATTATTAT
CGAAAAGCTTCAGCCCATGCATCTGCAACGGTACTACTCCCAAAAACTGCAAACCTTATCGAATAGAACCGTTCAATACC
ATCACCGGGTATTAAAAGAAGCACTCTCCCACGCAGTCCAATGGCAACTGCTCAACCGGAACCCAGCAGATGCGGTACAG
GCGCCTAAGAACAAACAAAAAGAAATCGAGCTGCCAGACCTATCAAATATCGACCGGATGATCCAGGCATCCAAAGACCA
CCCCGACCACATAATCATCATCTCAGCAGTATTCACCGGTATGAGAAGAGGCGAACTTCTTGGCTTACGTTGGCAAGACC
TCGACTTTGACAAAAACCTTCTCTATGTACGAAATACTTTGCAAAGGCTGCCCGACAAGGGAAAATTTTTTACCGAACCA
AAATCCAAGAAAAGCCGACGACAAATCATTATTCCTCATTTCTTAACTAACTTACTAAAAGACCATCGTAAAAAACAGCT
GGAGGAGCGGTTTAAGCTTGGGCACCTATATCAGGACCACGACCTAGTATTCCCAAGACCCGATGGCACACCAGCCGACC
CCGGCACCGTCAGCCATCGCTTTAAAGCTCTGGTTGATAAAATTGGCCTTTCGGGCCTGCGCTTTCATGATTTAAGGCAC
TTCCACGCCACCTTACTTCTAGCTGAAAATATTAACCCTAAAAAAGTACAGGAACGCCTGGGACACCAAACCATAAGTTT
AACTTTAGATGTTTACTCTCACCTAATTCCCAGCATGCAAAATGAGATCGCCGAAAAGCTCGAAGAGATATACGGGCACC
GATTCGGCACCGAAAAGAGAAAAGGCCAGTGA

Upstream 100 bases:

>100_bases
ATTGACAAAGGAATTCAAAAAGAAGAATTAGCAGACCATTTTAATGTCACTAAGCAGCTGCTGCGGTTTAGGTTGAAACT
TTTAAAACAGGAGGGATGAT

Downstream 100 bases:

>100_bases
TATACACTGACCTAATTCATGTGAAACCTTGATTTACTTGGTGCCCGGAGCCGGGGTCGAACCGGCACGGTCGTGAAACC
GCAGGATTTTAAGTCCTGTG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPGHLEKRHKSSWTIIIDLGKDPITNKRKRMVRGFKGTKKEAEKEMARLIAEYETGQYIEPSKTCLGDYMLRWLEDYGKP
NLAPTTYYSYSKIVEKHIIPSIGSIIIEKLQPMHLQRYYSQKLQTLSNRTVQYHHRVLKEALSHAVQWQLLNRNPADAVQ
APKNKQKEIELPDLSNIDRMIQASKDHPDHIIIISAVFTGMRRGELLGLRWQDLDFDKNLLYVRNTLQRLPDKGKFFTEP
KSKKSRRQIIIPHFLTNLLKDHRKKQLEERFKLGHLYQDHDLVFPRPDGTPADPGTVSHRFKALVDKIGLSGLRFHDLRH
FHATLLLAENINPKKVQERLGHQTISLTLDVYSHLIPSMQNEIAEKLEEIYGHRFGTEKRKGQ

Sequences:

>Translated_383_residues
MPGHLEKRHKSSWTIIIDLGKDPITNKRKRMVRGFKGTKKEAEKEMARLIAEYETGQYIEPSKTCLGDYMLRWLEDYGKP
NLAPTTYYSYSKIVEKHIIPSIGSIIIEKLQPMHLQRYYSQKLQTLSNRTVQYHHRVLKEALSHAVQWQLLNRNPADAVQ
APKNKQKEIELPDLSNIDRMIQASKDHPDHIIIISAVFTGMRRGELLGLRWQDLDFDKNLLYVRNTLQRLPDKGKFFTEP
KSKKSRRQIIIPHFLTNLLKDHRKKQLEERFKLGHLYQDHDLVFPRPDGTPADPGTVSHRFKALVDKIGLSGLRFHDLRH
FHATLLLAENINPKKVQERLGHQTISLTLDVYSHLIPSMQNEIAEKLEEIYGHRFGTEKRKGQ
>Mature_382_residues
PGHLEKRHKSSWTIIIDLGKDPITNKRKRMVRGFKGTKKEAEKEMARLIAEYETGQYIEPSKTCLGDYMLRWLEDYGKPN
LAPTTYYSYSKIVEKHIIPSIGSIIIEKLQPMHLQRYYSQKLQTLSNRTVQYHHRVLKEALSHAVQWQLLNRNPADAVQA
PKNKQKEIELPDLSNIDRMIQASKDHPDHIIIISAVFTGMRRGELLGLRWQDLDFDKNLLYVRNTLQRLPDKGKFFTEPK
SKKSRRQIIIPHFLTNLLKDHRKKQLEERFKLGHLYQDHDLVFPRPDGTPADPGTVSHRFKALVDKIGLSGLRFHDLRHF
HATLLLAENINPKKVQERLGHQTISLTLDVYSHLIPSMQNEIAEKLEEIYGHRFGTEKRKGQ

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787607, Length=248, Percent_Identity=22.9838709677419, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786748, Length=255, Percent_Identity=25.0980392156863, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44720; Mature: 44589

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHLEKRHKSSWTIIIDLGKDPITNKRKRMVRGFKGTKKEAEKEMARLIAEYETGQYIE
CCCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
PSKTCLGDYMLRWLEDYGKPNLAPTTYYSYSKIVEKHIIPSIGSIIIEKLQPMHLQRYYS
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QKLQTLSNRTVQYHHRVLKEALSHAVQWQLLNRNPADAVQAPKNKQKEIELPDLSNIDRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHH
IQASKDHPDHIIIISAVFTGMRRGELLGLRWQDLDFDKNLLYVRNTLQRLPDKGKFFTEP
HHCCCCCCCEEEEHHHHHHHHHCCCEECCEECCCCCCCCHHHHHHHHHHCCCCCCCCCCC
KSKKSRRQIIIPHFLTNLLKDHRKKQLEERFKLGHLYQDHDLVFPRPDGTPADPGTVSHR
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCCCCCCCHHHHH
FKALVDKIGLSGLRFHDLRHFHATLLLAENINPKKVQERLGHQTISLTLDVYSHLIPSMQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
NEIAEKLEEIYGHRFGTEKRKGQ
HHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PGHLEKRHKSSWTIIIDLGKDPITNKRKRMVRGFKGTKKEAEKEMARLIAEYETGQYIE
CCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
PSKTCLGDYMLRWLEDYGKPNLAPTTYYSYSKIVEKHIIPSIGSIIIEKLQPMHLQRYYS
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QKLQTLSNRTVQYHHRVLKEALSHAVQWQLLNRNPADAVQAPKNKQKEIELPDLSNIDRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHH
IQASKDHPDHIIIISAVFTGMRRGELLGLRWQDLDFDKNLLYVRNTLQRLPDKGKFFTEP
HHCCCCCCCEEEEHHHHHHHHHCCCEECCEECCCCCCCCHHHHHHHHHHCCCCCCCCCCC
KSKKSRRQIIIPHFLTNLLKDHRKKQLEERFKLGHLYQDHDLVFPRPDGTPADPGTVSHR
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCCCCCCCHHHHH
FKALVDKIGLSGLRFHDLRHFHATLLLAENINPKKVQERLGHQTISLTLDVYSHLIPSMQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
NEIAEKLEEIYGHRFGTEKRKGQ
HHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]