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The map label for this gene is yegE [C]

Identifier: 134298260

GI number: 134298260

Start: 411459

End: 413699

Strand: Reverse

Name: yegE [C]

Synonym: Dred_0383

Alternate gene names: 134298260

Gene position: 413699-411459 (Counterclockwise)

Preceding gene: 134298263

Following gene: 134298257

Centisome position: 11.47

GC content: 42.84

Gene sequence:

>2241_bases
ATGGAATATTACCAAAAAACTCCCCCAAGAAAAATACCAATTCAGACTAAAGACTCCTTGCTCAAAATCATTTCTGAACT
AGAGCAGAGATTGCAACAAATTACCAATAACATGTTAGATCTGTATACCGAAACAGACCTAGCGGGTATTATTCGATACG
TCGGTCCCTCTCACAAAACCATTTTAGGCTATGACCCAAAAGCACTCAAAGGAACATCAGTTTTCTCTCGCATTCATCCC
AAGGATATAAGTAAGGTAACCGATGCTTTTCAGACTGCGCTTAACTCAGCTTCTGAAATAATTGTAGAATATCAACTACA
ACATGCAACTGGTCATTATTTATGGGTTGAGTCCGTTGGTCGGTGCTTAGTGGAAGGAGATAGAAGAACAGGCGTTGTTA
TCAGCACCCGAAACATTACAAAACGAAAAGAGTTTGAAAATGCCCTGAGAGAAAGCGAATTTCGATTTCGGCAGATTACC
GAAAACATGCGCGACATCATTATACAAATTGATAAATGTGGAACTCTTACCTATGTCGGCCCATCTGTAAAGTTTCTCTT
GGGTTATCAACCTGAGAGGCTTTTAGGGAAAAAGGTGTTTGAATTATTGCACTCGGAGGATTACGATAAAACCACTAAAC
TATTTGCAAATAGTTTAGCAAACTATACGGAAGGCGAATTTGAATGTCGCTGTCGTCATGCAGACGGGCGCTATCTCTGG
CTGGAATGTGCAGGAAAAATACTATCAAATAGTCATGGTCAGGCCACAGGAGCTATTATCACTGCCAGGGATATAACGGA
TCGGAAAATGACGAAGCAGGCCCTCCTAGCAAGCGAAGAGCGAATCAGCCGTATAACTGAGAATATGCTTGACATTATGG
TTGAGCTAAATTCGGAAGGAATTACACAGTATGTCAGTCCCTCAGTTAAAACTGTTTTAGGATTTGATCCTAAAGACCTC
CTAGGAGTACCGGTATTTAAGAACGTTCATCCAGAAGACCTTGATCGGGTTCTTGAAGCCTATGAAAAAAGCATCAATCA
CTGGTCTTGTATGAGGGTTGATTTTCGTTATAAAAATGCACAGGGCTATTACCGCTGGTTGGAATTAATCGGCAATATCC
TGCAGGATGAGCATGGATCAGTGAGCACCAGTATCTTATGCCTACGTGATATCACCGAGCGCAAGTGGGCCGAACTACAA
ACAAAGTATTTCAGTATGCATGATCCCGTCACAGGACTCTATAACCGTACACACTTTGAGTTGGAGATGCGCCGACTGGA
AAACAGTTCTGAGCCTGTGGGCTTGATTGTTGCAGACTTGGACGGTCTAAAACTGATCAATGATACCATGGGCCACGAGG
TCGGAGACAATGCCCTAAGGGCCGTAGCCAATATATTAAAAATATCTTACCGCGAAGAAGATATTGTTGCTCGAATCGGT
GGAGACGAGTTAGCGGTTATACTGACAAATGTGTCTATGGATACCCTAAAGGTTGCTGTGTCTCGTTTAGAAAAAAACAT
CAAGGATTACAACATGGAAAACCCAGGAAGTCATTTAAGTTTGTCCATCGGTTATGCTCTGCGGGAACCTCCCACTAAAC
CTTTGAATGAGGTCTTTAAAGAAGCCGATTACTATATGTACCGTGCAAAGTTACACCATGCAAAAAGTACACGCAGTTCC
CTTGTACAAACTCTTATGAAAGCTCTGGAAGCCCGGGATTTTATCACAGAGGGTCACGGGGACCGCATGAAAAGTCTGGT
TGTAAACATAGGTAAAGCCCTCGGGTTACCCGAAAACAAAATCTACGACCTGCAGCTTTTTGCACATTTTCATGACATTG
GTAAAGTGGGTATTTCTGATAAGATTCTTTTTAAACCCACAAAACTTACACCGGACGAACATAATGAAATTAAACGTCAC
TGCGAGATTGGCTACCGCATTGCTCAAGCATCTCCGGAACTATTGCCCATAGCCGATTGGATTCTCAAGCACCATGAATG
GTGGAACGGACAAGGTTATCCCCTGGGATTAAAGGGAGAACAAATCCCTTTAGAATGCCGCATACTGGCCATTGCAGACG
CCTACGATGCCATGACCAGTGACCGTCCTTATCGAAAGGCCATCAGTCACCAAGAAGCAATTCGTGAGTTGGAACGCAAT
GCAGGAATACAGTTTGATTTATTTTTACTGCCAATGGCCGTCAAGGTTATTGAACAATCTCTGGCCTTCTCGGTAGATTA
A

Upstream 100 bases:

>100_bases
CTAATAATTTAATATTTTTCGACATAATATGAGATAATTTGCAGGAATTGGCAATTATTTGGCTAATACTATAAAAAAAG
TTCAAATGGAGATTCTTAAG

Downstream 100 bases:

>100_bases
TATATAAAAGGGCTGTGCTGAAACTTTTGTTTCGGCACAGCCCTTTTATCAAAATATAACTGTGGAACATGAAGAAAGAA
CTGGTTTATATTGAGATTTT

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 746

Protein sequence:

>746_residues
MEYYQKTPPRKIPIQTKDSLLKIISELEQRLQQITNNMLDLYTETDLAGIIRYVGPSHKTILGYDPKALKGTSVFSRIHP
KDISKVTDAFQTALNSASEIIVEYQLQHATGHYLWVESVGRCLVEGDRRTGVVISTRNITKRKEFENALRESEFRFRQIT
ENMRDIIIQIDKCGTLTYVGPSVKFLLGYQPERLLGKKVFELLHSEDYDKTTKLFANSLANYTEGEFECRCRHADGRYLW
LECAGKILSNSHGQATGAIITARDITDRKMTKQALLASEERISRITENMLDIMVELNSEGITQYVSPSVKTVLGFDPKDL
LGVPVFKNVHPEDLDRVLEAYEKSINHWSCMRVDFRYKNAQGYYRWLELIGNILQDEHGSVSTSILCLRDITERKWAELQ
TKYFSMHDPVTGLYNRTHFELEMRRLENSSEPVGLIVADLDGLKLINDTMGHEVGDNALRAVANILKISYREEDIVARIG
GDELAVILTNVSMDTLKVAVSRLEKNIKDYNMENPGSHLSLSIGYALREPPTKPLNEVFKEADYYMYRAKLHHAKSTRSS
LVQTLMKALEARDFITEGHGDRMKSLVVNIGKALGLPENKIYDLQLFAHFHDIGKVGISDKILFKPTKLTPDEHNEIKRH
CEIGYRIAQASPELLPIADWILKHHEWWNGQGYPLGLKGEQIPLECRILAIADAYDAMTSDRPYRKAISHQEAIRELERN
AGIQFDLFLLPMAVKVIEQSLAFSVD

Sequences:

>Translated_746_residues
MEYYQKTPPRKIPIQTKDSLLKIISELEQRLQQITNNMLDLYTETDLAGIIRYVGPSHKTILGYDPKALKGTSVFSRIHP
KDISKVTDAFQTALNSASEIIVEYQLQHATGHYLWVESVGRCLVEGDRRTGVVISTRNITKRKEFENALRESEFRFRQIT
ENMRDIIIQIDKCGTLTYVGPSVKFLLGYQPERLLGKKVFELLHSEDYDKTTKLFANSLANYTEGEFECRCRHADGRYLW
LECAGKILSNSHGQATGAIITARDITDRKMTKQALLASEERISRITENMLDIMVELNSEGITQYVSPSVKTVLGFDPKDL
LGVPVFKNVHPEDLDRVLEAYEKSINHWSCMRVDFRYKNAQGYYRWLELIGNILQDEHGSVSTSILCLRDITERKWAELQ
TKYFSMHDPVTGLYNRTHFELEMRRLENSSEPVGLIVADLDGLKLINDTMGHEVGDNALRAVANILKISYREEDIVARIG
GDELAVILTNVSMDTLKVAVSRLEKNIKDYNMENPGSHLSLSIGYALREPPTKPLNEVFKEADYYMYRAKLHHAKSTRSS
LVQTLMKALEARDFITEGHGDRMKSLVVNIGKALGLPENKIYDLQLFAHFHDIGKVGISDKILFKPTKLTPDEHNEIKRH
CEIGYRIAQASPELLPIADWILKHHEWWNGQGYPLGLKGEQIPLECRILAIADAYDAMTSDRPYRKAISHQEAIRELERN
AGIQFDLFLLPMAVKVIEQSLAFSVD
>Mature_746_residues
MEYYQKTPPRKIPIQTKDSLLKIISELEQRLQQITNNMLDLYTETDLAGIIRYVGPSHKTILGYDPKALKGTSVFSRIHP
KDISKVTDAFQTALNSASEIIVEYQLQHATGHYLWVESVGRCLVEGDRRTGVVISTRNITKRKEFENALRESEFRFRQIT
ENMRDIIIQIDKCGTLTYVGPSVKFLLGYQPERLLGKKVFELLHSEDYDKTTKLFANSLANYTEGEFECRCRHADGRYLW
LECAGKILSNSHGQATGAIITARDITDRKMTKQALLASEERISRITENMLDIMVELNSEGITQYVSPSVKTVLGFDPKDL
LGVPVFKNVHPEDLDRVLEAYEKSINHWSCMRVDFRYKNAQGYYRWLELIGNILQDEHGSVSTSILCLRDITERKWAELQ
TKYFSMHDPVTGLYNRTHFELEMRRLENSSEPVGLIVADLDGLKLINDTMGHEVGDNALRAVANILKISYREEDIVARIG
GDELAVILTNVSMDTLKVAVSRLEKNIKDYNMENPGSHLSLSIGYALREPPTKPLNEVFKEADYYMYRAKLHHAKSTRSS
LVQTLMKALEARDFITEGHGDRMKSLVVNIGKALGLPENKIYDLQLFAHFHDIGKVGISDKILFKPTKLTPDEHNEIKRH
CEIGYRIAQASPELLPIADWILKHHEWWNGQGYPLGLKGEQIPLECRILAIADAYDAMTSDRPYRKAISHQEAIRELERN
AGIQFDLFLLPMAVKVIEQSLAFSVD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=359, Percent_Identity=25.0696378830084, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787262, Length=156, Percent_Identity=32.6923076923077, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786584, Length=154, Percent_Identity=35.0649350649351, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081881, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=36.25, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787541, Length=271, Percent_Identity=28.0442804428044, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693134, Length=194, Percent_Identity=34.5360824742268, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=32.7044025157233, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082007, Length=115, Percent_Identity=32.1739130434783, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=146, Percent_Identity=29.4520547945205, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 85139; Mature: 85139

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYYQKTPPRKIPIQTKDSLLKIISELEQRLQQITNNMLDLYTETDLAGIIRYVGPSHKT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ILGYDPKALKGTSVFSRIHPKDISKVTDAFQTALNSASEIIVEYQLQHATGHYLWVESVG
EEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCEEEHHHHH
RCLVEGDRRTGVVISTRNITKRKEFENALRESEFRFRQITENMRDIIIQIDKCGTLTYVG
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEC
PSVKFLLGYQPERLLGKKVFELLHSEDYDKTTKLFANSLANYTEGEFECRCRHADGRYLW
CCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEE
LECAGKILSNSHGQATGAIITARDITDRKMTKQALLASEERISRITENMLDIMVELNSEG
HHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ITQYVSPSVKTVLGFDPKDLLGVPVFKNVHPEDLDRVLEAYEKSINHWSCMRVDFRYKNA
CHHHCCCCHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECC
QGYYRWLELIGNILQDEHGSVSTSILCLRDITERKWAELQTKYFSMHDPVTGLYNRTHFE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
LEMRRLENSSEPVGLIVADLDGLKLINDTMGHEVGDNALRAVANILKISYREEDIVARIG
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEC
GDELAVILTNVSMDTLKVAVSRLEKNIKDYNMENPGSHLSLSIGYALREPPTKPLNEVFK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
EADYYMYRAKLHHAKSTRSSLVQTLMKALEARDFITEGHGDRMKSLVVNIGKALGLPENK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
IYDLQLFAHFHDIGKVGISDKILFKPTKLTPDEHNEIKRHCEIGYRIAQASPELLPIADW
EEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCEEEECCCCCCCHHHHH
ILKHHEWWNGQGYPLGLKGEQIPLECRILAIADAYDAMTSDRPYRKAISHQEAIRELERN
HHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHC
AGIQFDLFLLPMAVKVIEQSLAFSVD
CCCEEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEYYQKTPPRKIPIQTKDSLLKIISELEQRLQQITNNMLDLYTETDLAGIIRYVGPSHKT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ILGYDPKALKGTSVFSRIHPKDISKVTDAFQTALNSASEIIVEYQLQHATGHYLWVESVG
EEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCEEEHHHHH
RCLVEGDRRTGVVISTRNITKRKEFENALRESEFRFRQITENMRDIIIQIDKCGTLTYVG
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEC
PSVKFLLGYQPERLLGKKVFELLHSEDYDKTTKLFANSLANYTEGEFECRCRHADGRYLW
CCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEE
LECAGKILSNSHGQATGAIITARDITDRKMTKQALLASEERISRITENMLDIMVELNSEG
HHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ITQYVSPSVKTVLGFDPKDLLGVPVFKNVHPEDLDRVLEAYEKSINHWSCMRVDFRYKNA
CHHHCCCCHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECC
QGYYRWLELIGNILQDEHGSVSTSILCLRDITERKWAELQTKYFSMHDPVTGLYNRTHFE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
LEMRRLENSSEPVGLIVADLDGLKLINDTMGHEVGDNALRAVANILKISYREEDIVARIG
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEC
GDELAVILTNVSMDTLKVAVSRLEKNIKDYNMENPGSHLSLSIGYALREPPTKPLNEVFK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
EADYYMYRAKLHHAKSTRSSLVQTLMKALEARDFITEGHGDRMKSLVVNIGKALGLPENK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
IYDLQLFAHFHDIGKVGISDKILFKPTKLTPDEHNEIKRHCEIGYRIAQASPELLPIADW
EEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCEEEECCCCCCCHHHHH
ILKHHEWWNGQGYPLGLKGEQIPLECRILAIADAYDAMTSDRPYRKAISHQEAIRELERN
HHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHC
AGIQFDLFLLPMAVKVIEQSLAFSVD
CCCEEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]