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The map label for this gene is hdrA2 [H]

Identifier: 134298233

GI number: 134298233

Start: 375811

End: 377793

Strand: Reverse

Name: hdrA2 [H]

Synonym: Dred_0356

Alternate gene names: 134298233

Gene position: 377793-375811 (Counterclockwise)

Preceding gene: 134298234

Following gene: 134298232

Centisome position: 10.47

GC content: 47.25

Gene sequence:

>1983_bases
ATGAACAGAATTGGCGTTTTTGTTTGCTGGTGTGGTTCCAATATAGGCAGTGTTGTTGATGTACCGAGATTGGCTACGGA
AGCAGCCAAGTTTCCCGGAGTGGTTTTTAGCACCGATTATAAATATATGTGTTCAGTACCAGGACAAGATTTAATTGTTC
AGAAAATCAGTGAATATCGCTTGGACAAAGTGGTAATAGCATCTTGCTCCCCACGGTTACATGAGCAAACCTTTCGAAAG
ACCCTAGAAAGGGCCGGGCTTAATCCATTTATGATGAGAATTGCCAATATCCGGGAACAGTGTGCCTGGGTACACAGCCG
GCAAAAAGATGGAGCTACGGAAAAGGCCATTGCACTGGTACGGCGGGCTGTCGCTAAAGCGAACAACACAGAGCCCCTAT
ATGAAGAAAGGATTCCGGTTACCAAGCGGGCACTGGTCATTGGCGGAGGTATTGCTGGTATTCAGGCTGCCCTGGATATT
GCTGATGCCGGCCATGAAGTTGTGCTGGTGGAACGAGAACCAACCATTGGCGGTAAATCCGCTATGCTTGATAAAACCTT
CCCCACGCTGGATTGCAGTGGCTGAATTGTCACCCCCAAGATGGTTGCTGTGGTACAGCACCCTAACATTAAGCTTTATA
CCTTTGCTGAGGTTTGCGAGGTAAGCGGCTTTATCGGAAACTTTAATGTTCGAATTAAACAAAAACCAAAATATGTGGAC
CATAACAAATGTACAGGCTGTGGCACTTGCTGGGAAAAATGTCCAGCTAAGGTCCCCAGCGAGTATAACCTACACCTGGG
ACAAAGAAAAGCCATTTACATCAGTTCTCCCCAGGCTGTACCGAACAAGCCAATTATTGACCCAAAGGGATGCCGTATGC
TTTTAAGTGGTAAATGCGGTGTCTGCCAGAAAGTTTGCCAGGCGGAGGCAATCAATTATAAGGATACAGAGCAATTTTTT
GAAGAACAAGTAGGGGCTGTGGTCATGGCAACTGGCTATGACTTGTTTGATTGGGCTGGTTCTTACGGAGAATACGGCCA
CAGTAAGTATCCAGATGTCATCAGCAGCTTGCAATTTGAACGACTACTTAACAGTTCCGGTCCTACCGGTGGTAAAATAC
TTCGGCCGTCGGACAGCAAAGAACCTAAAAGTATAGTGTTTATTAAATGTGTGGGCTCCAGGGATGAATCAAAGGGTAAG
TCTTACTGCTCTAGGGCCTGCTGCATGTACACGGCTAAACACGCTCAACAGATACTGGAAAAGATTGAAGGGGCCAGAGT
CTATGTCTTCTACATGGATGTGCGTACTCCAGGAAAGGGTTATGAGGAATTTTATCAGCGTTCGGTGAATGAGGGTGCTT
GTTACATAAGGGGTCGAGTTTCAAAAATTTACCCCAAGGGTGAAAAATTAGTAGTCAGGGGTGCAGACACCCTGCTGGGG
CGACCGGTGGAGGTTGAGACAGACCTGGTGGTATTGGCCACAGCTATGACACCCAGCAGAGGTTCGGATGAATTGGCCAA
GGTAGTTGGGTTTACCACAGACAAAGATGGTTTTTATCAGGAAGCCCACCCCAAGCTTAAGCCTGTGGAAACCAATACCG
GCGGTATCTTTTTAGCTGGATGTTGCCAGGGTCCCAAGGATATTCCAGACACTGTATCCCAGGCCAGTGCAGCAGCCGCC
AAGGTAATCGTGCTATTATCTAAAGACGAACTAGCCACCAACCCAATGGTGTCCCAAATTGATGAAAGACGTTGTACCGG
ATGTATGGCCTGCCGTGATGTTTGTCCCTTCAATGCCATTGAAGAAAAATTAATCACTGATAAATCAATGGGGCAGGGAG
TCCAACGCACTGTGGCTGCTATTAATACTGGTTTATGCCAGGGTTGTGGTGCCTGTGCAGCCACATGCCGCTGCGGTGCC
GCAGATCTTAAGGGTTTTACAAACCAGCAGGTAATGTCTGAGATCATAGCCCTATGCATATAA

Upstream 100 bases:

>100_bases
TTATCTTTGGGGATAGAACCCAATTGCCTGGGTATGGACCTAATGACAGCTAAAGCTATGTTATCCAGAATAAGCTAGTT
TAGCCAGAGGGGGCGAAGAT

Downstream 100 bases:

>100_bases
GGTTTCTATTTTAGAGGAATTAGTCACCTCCTACCATTAGGGGAGGTGATTCTTTTTTTATCATGATGGCATAGGTTTTC
CTATGAAAAGCGAATGACTC

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MNRIGVFVCWCGSNIGSVVDVPRLATEAAKFPGVVFSTDYKYMCSVPGQDLIVQKISEYRLDKVVIASCSPRLHEQTFRK
TLERAGLNPFMMRIANIREQCAWVHSRQKDGATEKAIALVRRAVAKANNTEPLYEERIPVTKRALVIGGGIAGIQAALDI
ADAGHEVVLVEREPTIGGKSAMLDKTFPTLDCSGUIVTPKMVAVVQHPNIKLYTFAEVCEVSGFIGNFNVRIKQKPKYVD
HNKCTGCGTCWEKCPAKVPSEYNLHLGQRKAIYISSPQAVPNKPIIDPKGCRMLLSGKCGVCQKVCQAEAINYKDTEQFF
EEQVGAVVMATGYDLFDWAGSYGEYGHSKYPDVISSLQFERLLNSSGPTGGKILRPSDSKEPKSIVFIKCVGSRDESKGK
SYCSRACCMYTAKHAQQILEKIEGARVYVFYMDVRTPGKGYEEFYQRSVNEGACYIRGRVSKIYPKGEKLVVRGADTLLG
RPVEVETDLVVLATAMTPSRGSDELAKVVGFTTDKDGFYQEAHPKLKPVETNTGGIFLAGCCQGPKDIPDTVSQASAAAA
KVIVLLSKDELATNPMVSQIDERRCTGCMACRDVCPFNAIEEKLITDKSMGQGVQRTVAAINTGLCQGCGACAATCRCGA
ADLKGFTNQQVMSEIIALCI

Sequences:

>Translated_660_residues
MNRIGVFVCWCGSNIGSVVDVPRLATEAAKFPGVVFSTDYKYMCSVPGQDLIVQKISEYRLDKVVIASCSPRLHEQTFRK
TLERAGLNPFMMRIANIREQCAWVHSRQKDGATEKAIALVRRAVAKANNTEPLYEERIPVTKRALVIGGGIAGIQAALDI
ADAGHEVVLVEREPTIGGKSAMLDKTFPTLDCSG*IVTPKMVAVVQHPNIKLYTFAEVCEVSGFIGNFNVRIKQKPKYVD
HNKCTGCGTCWEKCPAKVPSEYNLHLGQRKAIYISSPQAVPNKPIIDPKGCRMLLSGKCGVCQKVCQAEAINYKDTEQFF
EEQVGAVVMATGYDLFDWAGSYGEYGHSKYPDVISSLQFERLLNSSGPTGGKILRPSDSKEPKSIVFIKCVGSRDESKGK
SYCSRACCMYTAKHAQQILEKIEGARVYVFYMDVRTPGKGYEEFYQRSVNEGACYIRGRVSKIYPKGEKLVVRGADTLLG
RPVEVETDLVVLATAMTPSRGSDELAKVVGFTTDKDGFYQEAHPKLKPVETNTGGIFLAGCCQGPKDIPDTVSQASAAAA
KVIVLLSKDELATNPMVSQIDERRCTGCMACRDVCPFNAIEEKLITDKSMGQGVQRTVAAINTGLCQGCGACAATCRCGA
ADLKGFTNQQVMSEIIALCI
>Mature_660_residues
MNRIGVFVCWCGSNIGSVVDVPRLATEAAKFPGVVFSTDYKYMCSVPGQDLIVQKISEYRLDKVVIASCSPRLHEQTFRK
TLERAGLNPFMMRIANIREQCAWVHSRQKDGATEKAIALVRRAVAKANNTEPLYEERIPVTKRALVIGGGIAGIQAALDI
ADAGHEVVLVEREPTIGGKSAMLDKTFPTLDCSG*IVTPKMVAVVQHPNIKLYTFAEVCEVSGFIGNFNVRIKQKPKYVD
HNKCTGCGTCWEKCPAKVPSEYNLHLGQRKAIYISSPQAVPNKPIIDPKGCRMLLSGKCGVCQKVCQAEAINYKDTEQFF
EEQVGAVVMATGYDLFDWAGSYGEYGHSKYPDVISSLQFERLLNSSGPTGGKILRPSDSKEPKSIVFIKCVGSRDESKGK
SYCSRACCMYTAKHAQQILEKIEGARVYVFYMDVRTPGKGYEEFYQRSVNEGACYIRGRVSKIYPKGEKLVVRGADTLLG
RPVEVETDLVVLATAMTPSRGSDELAKVVGFTTDKDGFYQEAHPKLKPVETNTGGIFLAGCCQGPKDIPDTVSQASAAAA
KVIVLLSKDELATNPMVSQIDERRCTGCMACRDVCPFNAIEEKLITDKSMGQGVQRTVAAINTGLCQGCGACAATCRCGA
ADLKGFTNQQVMSEIIALCI

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 71854; Mature: 71854

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGVFVCWCGSNIGSVVDVPRLATEAAKFPGVVFSTDYKYMCSVPGQDLIVQKISEYR
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCCHHHHHHHHHHHH
LDKVVIASCSPRLHEQTFRKTLERAGLNPFMMRIANIREQCAWVHSRQKDGATEKAIALV
HCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RRAVAKANNTEPLYEERIPVTKRALVIGGGIAGIQAALDIADAGHEVVLVEREPTIGGKS
HHHHHHCCCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCH
AMLDKTFPTLDCSGIVTPKMVAVVQHPNIKLYTFAEVCEVSGFIGNFNVRIKQKPKYVDH
HHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHCCCEECEEEEEECCCCCCCC
NKCTGCGTCWEKCPAKVPSEYNLHLGQRKAIYISSPQAVPNKPIIDPKGCRMLLSGKCGV
CCCCCCCHHHHHCCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCHH
CQKVCQAEAINYKDTEQFFEEQVGAVVMATGYDLFDWAGSYGEYGHSKYPDVISSLQFER
HHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LLNSSGPTGGKILRPSDSKEPKSIVFIKCVGSRDESKGKSYCSRACCMYTAKHAQQILEK
HHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEGARVYVFYMDVRTPGKGYEEFYQRSVNEGACYIRGRVSKIYPKGEKLVVRGADTLLGR
CCCCEEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECHHCCCCCCCEEEEECCHHHCCC
PVEVETDLVVLATAMTPSRGSDELAKVVGFTTDKDGFYQEAHPKLKPVETNTGGIFLAGC
CCEECCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCEECCCCCEEEEEC
CQGPKDIPDTVSQASAAAAKVIVLLSKDELATNPMVSQIDERRCTGCMACRDVCPFNAIE
CCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
EKLITDKSMGQGVQRTVAAINTGLCQGCGACAATCRCGAADLKGFTNQQVMSEIIALCI
HHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIGVFVCWCGSNIGSVVDVPRLATEAAKFPGVVFSTDYKYMCSVPGQDLIVQKISEYR
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCCHHHHHHHHHHHH
LDKVVIASCSPRLHEQTFRKTLERAGLNPFMMRIANIREQCAWVHSRQKDGATEKAIALV
HCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RRAVAKANNTEPLYEERIPVTKRALVIGGGIAGIQAALDIADAGHEVVLVEREPTIGGKS
HHHHHHCCCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCH
AMLDKTFPTLDCSGIVTPKMVAVVQHPNIKLYTFAEVCEVSGFIGNFNVRIKQKPKYVDH
HHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHCCCEECEEEEEECCCCCCCC
NKCTGCGTCWEKCPAKVPSEYNLHLGQRKAIYISSPQAVPNKPIIDPKGCRMLLSGKCGV
CCCCCCCHHHHHCCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCHH
CQKVCQAEAINYKDTEQFFEEQVGAVVMATGYDLFDWAGSYGEYGHSKYPDVISSLQFER
HHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LLNSSGPTGGKILRPSDSKEPKSIVFIKCVGSRDESKGKSYCSRACCMYTAKHAQQILEK
HHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEGARVYVFYMDVRTPGKGYEEFYQRSVNEGACYIRGRVSKIYPKGEKLVVRGADTLLGR
CCCCEEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECHHCCCCCCCEEEEECCHHHCCC
PVEVETDLVVLATAMTPSRGSDELAKVVGFTTDKDGFYQEAHPKLKPVETNTGGIFLAGC
CCEECCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCEECCCCCEEEEEC
CQGPKDIPDTVSQASAAAAKVIVLLSKDELATNPMVSQIDERRCTGCMACRDVCPFNAIE
CCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
EKLITDKSMGQGVQRTVAAINTGLCQGCGACAATCRCGAADLKGFTNQQVMSEIIALCI
HHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]