Click here to switch to the map view.

The map label for this gene is gamP [H]

Identifier: 134298209

GI number: 134298209

Start: 345821

End: 347689

Strand: Reverse

Name: gamP [H]

Synonym: Dred_0332

Alternate gene names: 134298209

Gene position: 347689-345821 (Counterclockwise)

Preceding gene: 134298210

Following gene: 134298208

Centisome position: 9.64

GC content: 44.03

Gene sequence:

>1869_bases
ATGAAAAAAGCATTTAAGTATTTACAGATGGTTGGACAATCTTTAATGCTGCCTGTATCTGTGTTACCTGCTGCCGGTTT
ACTGCTCAGGTTTGGTGAGAAAGATTTACTCAACATGCCTGCCATGAAGGAAGCTGGGTTGGCTATCTTTGCCAACCTAC
CCTTGATATTTGCCGTGGGGGTTGCCATTGGTTTTTCTGGTGGACAGTCGGTAGCCGCTCTGGCCGCTGTAGTAGGGCAG
TTAATCCTGTTAGCAGTACTGAAAGCAGTGGACCCCAGTATTAACATGGGGGTATTTTCCGGCATTATCATGGGTATTAC
CGCTGCCCTATTGTATAAAAGGTTTTATCAAATTAAGCTGCCCCAATACCTGGGCTTTTTCGCCGGGAAGCGCTTTGTTC
CCATTATTACCGCTGTGGCCGGTGTAGTGATTGCTTTAATTTCTGCCGTGGTTTGGCCCAGCATACAGAATGTCATTGAT
GCCGTAGGTCAGGTTGCGGTTAGTTCCAGTTTTGGTCCTGCCTTGTTTGCCGCCGGCAAACGTTTACTGATACCAGTTGG
CCTGCACCACGTTTACTATCCCTCTTTCTTGTATGAATTCGGTCAGTATGTAACTGCTGCCGGGGAAATTGTAAAAGGAG
ATTTTAACCGTTACTTCGCTGGGGATCCAACAGCCGGAACCTTTATGGCCAGCGAGTTTCCCATAATGATGTTTGGTCTG
CCCGCTGCCGCCTTTGCCATTTACCGTAACGCCAGGCCCGAGCGCAAAAAAGCTATCGCAGGATTAATGGCCAGCGCAGC
CTTTACCTCGTTCCTGACGGGTATTACCGAACCAATAGAATTTTCCTTTATTTTTGTGGCACCTGTGTTATTTGTCTTCC
ATGTACTAATGGCCGGTGTGTCTGGTTTTGTAACAAATTTGCTTGATATTCATTTAGGATTTACTTTCTCTGCCTCTTTC
ATCGATTATCTATTGTCCTATAAATATGGTCATAACCAGCTGTTGCTGTGGCCAGTGGGCCTGGTTGTCGGAGGTCTGTA
TTTTGTAGTCTTTAATACCGCTATAAAAATGTTGAACTTAAAAACACCGGGCCGAGAAGATGAAATTACTGCAGTAGAAA
ACCAAGGTACCGGTTCTGATTTAGCGCACAAGGTATTAGATGCCCTGGGAGGAGCTAATAATATTGAGATATTGGATGCT
TGCATTACCCGTTTGCGGGTAACTGTAAAAGATCCAGACATGGTTAAAAAAGATGTGTTTAAGGCTCTAGGTGCTTCTGG
AGTTATGGAAATGGGTAAAAACCTGCAAATTATTTTTGGCACCCAATCCGACAGCTTAAAAGAAGAAATCCGCAGTCTAA
TGACTAATACTGTTTCAGCCACAGCAGAAGGGGCTAAACCCTTACCTGAGCTTAACGTTTCTGCCAGCAAAACTATGATT
AAGGCTCCTGCCAGCGGTAAGGTTATTCCCTTAGAACAGGTACCTGATGAGACCTTTAAACAAAAACTGCTGGGCAACGG
AGTAGCCATTGAGCCAGTAGAGGGTACCTTTATAGCACCTGTGGCAGGAACTGTTGTTCAAGTATTTCCTACCAACCATG
CTTTAACCATAAAAACAGAAAACGGCATAGAAATCCTGTTGCATGTAGGCATTAATACCGTTTCCTTAAAGGGCCAAGGC
TTTAAAGCTCTGGTTTCCGAAGGGCAAAAGGTTACGGTAGGACAAAAACTTCTTGAGGTAGATTTAAAGCAGATTGAAAA
GGCTGGCTTATCTACCATTACTCCTGTAATTATCATTGGATCTGAGGATATGGAAATAACCCCTGCAAATGAAGTAACTT
CTGGAGAAGATACCATTTTACAAATTTAA

Upstream 100 bases:

>100_bases
CTGATCTGCCAAAAAAGCATAATGTGCGCGCCATTAGCTTTTTTTGAACAAATAAAAAACAAATTAAAAAGAAAAACTAA
TTAAAAAGGAAGTGAAGGGC

Downstream 100 bases:

>100_bases
GAGTAATTAGTTTATAGAAAGTGGAGGCATAAAATGATTAAACAAGTAGTCACTATTGTTAACCCAACAGGAATTCATGC
CAGACCGGCGGCACATATAG

Product: PTS system, glucose subfamily, IIA subunit

Products: NA

Alternate protein names: Glucosamine permease IIC component; PTS system glucosamine-specific EIIC component; Glucosamine-specific phosphotransferase enzyme IIB component; PTS system glucosamine-specific EIIB component; Glucosamine-specific phosphotransferase enzyme IIA component; PTS system glucosamine-specific EIIA component [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MKKAFKYLQMVGQSLMLPVSVLPAAGLLLRFGEKDLLNMPAMKEAGLAIFANLPLIFAVGVAIGFSGGQSVAALAAVVGQ
LILLAVLKAVDPSINMGVFSGIIMGITAALLYKRFYQIKLPQYLGFFAGKRFVPIITAVAGVVIALISAVVWPSIQNVID
AVGQVAVSSSFGPALFAAGKRLLIPVGLHHVYYPSFLYEFGQYVTAAGEIVKGDFNRYFAGDPTAGTFMASEFPIMMFGL
PAAAFAIYRNARPERKKAIAGLMASAAFTSFLTGITEPIEFSFIFVAPVLFVFHVLMAGVSGFVTNLLDIHLGFTFSASF
IDYLLSYKYGHNQLLLWPVGLVVGGLYFVVFNTAIKMLNLKTPGREDEITAVENQGTGSDLAHKVLDALGGANNIEILDA
CITRLRVTVKDPDMVKKDVFKALGASGVMEMGKNLQIIFGTQSDSLKEEIRSLMTNTVSATAEGAKPLPELNVSASKTMI
KAPASGKVIPLEQVPDETFKQKLLGNGVAIEPVEGTFIAPVAGTVVQVFPTNHALTIKTENGIEILLHVGINTVSLKGQG
FKALVSEGQKVTVGQKLLEVDLKQIEKAGLSTITPVIIIGSEDMEITPANEVTSGEDTILQI

Sequences:

>Translated_622_residues
MKKAFKYLQMVGQSLMLPVSVLPAAGLLLRFGEKDLLNMPAMKEAGLAIFANLPLIFAVGVAIGFSGGQSVAALAAVVGQ
LILLAVLKAVDPSINMGVFSGIIMGITAALLYKRFYQIKLPQYLGFFAGKRFVPIITAVAGVVIALISAVVWPSIQNVID
AVGQVAVSSSFGPALFAAGKRLLIPVGLHHVYYPSFLYEFGQYVTAAGEIVKGDFNRYFAGDPTAGTFMASEFPIMMFGL
PAAAFAIYRNARPERKKAIAGLMASAAFTSFLTGITEPIEFSFIFVAPVLFVFHVLMAGVSGFVTNLLDIHLGFTFSASF
IDYLLSYKYGHNQLLLWPVGLVVGGLYFVVFNTAIKMLNLKTPGREDEITAVENQGTGSDLAHKVLDALGGANNIEILDA
CITRLRVTVKDPDMVKKDVFKALGASGVMEMGKNLQIIFGTQSDSLKEEIRSLMTNTVSATAEGAKPLPELNVSASKTMI
KAPASGKVIPLEQVPDETFKQKLLGNGVAIEPVEGTFIAPVAGTVVQVFPTNHALTIKTENGIEILLHVGINTVSLKGQG
FKALVSEGQKVTVGQKLLEVDLKQIEKAGLSTITPVIIIGSEDMEITPANEVTSGEDTILQI
>Mature_622_residues
MKKAFKYLQMVGQSLMLPVSVLPAAGLLLRFGEKDLLNMPAMKEAGLAIFANLPLIFAVGVAIGFSGGQSVAALAAVVGQ
LILLAVLKAVDPSINMGVFSGIIMGITAALLYKRFYQIKLPQYLGFFAGKRFVPIITAVAGVVIALISAVVWPSIQNVID
AVGQVAVSSSFGPALFAAGKRLLIPVGLHHVYYPSFLYEFGQYVTAAGEIVKGDFNRYFAGDPTAGTFMASEFPIMMFGL
PAAAFAIYRNARPERKKAIAGLMASAAFTSFLTGITEPIEFSFIFVAPVLFVFHVLMAGVSGFVTNLLDIHLGFTFSASF
IDYLLSYKYGHNQLLLWPVGLVVGGLYFVVFNTAIKMLNLKTPGREDEITAVENQGTGSDLAHKVLDALGGANNIEILDA
CITRLRVTVKDPDMVKKDVFKALGASGVMEMGKNLQIIFGTQSDSLKEEIRSLMTNTVSATAEGAKPLPELNVSASKTMI
KAPASGKVIPLEQVPDETFKQKLLGNGVAIEPVEGTFIAPVAGTVVQVFPTNHALTIKTENGIEILLHVGINTVSLKGQG
FKALVSEGQKVTVGQKLLEVDLKQIEKAGLSTITPVIIIGSEDMEITPANEVTSGEDTILQI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=642, Percent_Identity=43.4579439252336, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1787343, Length=479, Percent_Identity=45.7202505219207, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1787908, Length=522, Percent_Identity=33.7164750957854, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1788757, Length=143, Percent_Identity=42.6573426573427, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790159, Length=160, Percent_Identity=40, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66343; Mature: 66343

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAFKYLQMVGQSLMLPVSVLPAAGLLLRFGEKDLLNMPAMKEAGLAIFANLPLIFAVG
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHCCCCHHHCCEEEEECCHHHHHHH
VAIGFSGGQSVAALAAVVGQLILLAVLKAVDPSINMGVFSGIIMGITAALLYKRFYQIKL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PQYLGFFAGKRFVPIITAVAGVVIALISAVVWPSIQNVIDAVGQVAVSSSFGPALFAAGK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
RLLIPVGLHHVYYPSFLYEFGQYVTAAGEIVKGDFNRYFAGDPTAGTFMASEFPIMMFGL
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEECCCCCEEEECC
PAAAFAIYRNARPERKKAIAGLMASAAFTSFLTGITEPIEFSFIFVAPVLFVFHVLMAGV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SGFVTNLLDIHLGFTFSASFIDYLLSYKYGHNQLLLWPVGLVVGGLYFVVFNTAIKMLNL
HHHHHHHHHHHHCCEEHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
KTPGREDEITAVENQGTGSDLAHKVLDALGGANNIEILDACITRLRVTVKDPDMVKKDVF
CCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHHHHH
KALGASGVMEMGKNLQIIFGTQSDSLKEEIRSLMTNTVSATAEGAKPLPELNVSASKTMI
HHHCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
KAPASGKVIPLEQVPDETFKQKLLGNGVAIEPVEGTFIAPVAGTVVQVFPTNHALTIKTE
ECCCCCCEEEHHHCCCHHHHHHHHCCCCEEECCCCCEECCCCCCEEEEECCCEEEEEEEC
NGIEILLHVGINTVSLKGQGFKALVSEGQKVTVGQKLLEVDLKQIEKAGLSTITPVIIIG
CCCEEEEEECCEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEC
SEDMEITPANEVTSGEDTILQI
CCCCEECCCCCCCCCCCCEEEC
>Mature Secondary Structure
MKKAFKYLQMVGQSLMLPVSVLPAAGLLLRFGEKDLLNMPAMKEAGLAIFANLPLIFAVG
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHCCCCHHHCCEEEEECCHHHHHHH
VAIGFSGGQSVAALAAVVGQLILLAVLKAVDPSINMGVFSGIIMGITAALLYKRFYQIKL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PQYLGFFAGKRFVPIITAVAGVVIALISAVVWPSIQNVIDAVGQVAVSSSFGPALFAAGK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
RLLIPVGLHHVYYPSFLYEFGQYVTAAGEIVKGDFNRYFAGDPTAGTFMASEFPIMMFGL
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEECCCCCEEEECC
PAAAFAIYRNARPERKKAIAGLMASAAFTSFLTGITEPIEFSFIFVAPVLFVFHVLMAGV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SGFVTNLLDIHLGFTFSASFIDYLLSYKYGHNQLLLWPVGLVVGGLYFVVFNTAIKMLNL
HHHHHHHHHHHHCCEEHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
KTPGREDEITAVENQGTGSDLAHKVLDALGGANNIEILDACITRLRVTVKDPDMVKKDVF
CCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHHHHH
KALGASGVMEMGKNLQIIFGTQSDSLKEEIRSLMTNTVSATAEGAKPLPELNVSASKTMI
HHHCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
KAPASGKVIPLEQVPDETFKQKLLGNGVAIEPVEGTFIAPVAGTVVQVFPTNHALTIKTE
ECCCCCCEEEHHHCCCHHHHHHHHCCCCEEECCCCCEECCCCCCEEEEECCCEEEEEEEC
NGIEILLHVGINTVSLKGQGFKALVSEGQKVTVGQKLLEVDLKQIEKAGLSTITPVIIIG
CCCEEEEEECCEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEC
SEDMEITPANEVTSGEDTILQI
CCCCEECCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 7751298 [H]