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The map label for this gene is yycF [H]

Identifier: 126697149

GI number: 126697149

Start: 1533412

End: 1534158

Strand: Reverse

Name: yycF [H]

Synonym: P9301_18111

Alternate gene names: 126697149

Gene position: 1534158-1533412 (Counterclockwise)

Preceding gene: 126697150

Following gene: 126697148

Centisome position: 93.44

GC content: 37.88

Gene sequence:

>747_bases
ATGTCAAAAGCAAGAATTTTAGTTGTTGATGATGAACCAGCAGTTTTGAAGGTATTAGTTACAAGGCTTCAACTAGCTGG
ATATCAAGTTTATTCAGCCACTAATGGCGAAGAAGCTATTGAATCTTTCCACAGGGATTCGCCAGATTTAATAGTTCTTG
ATGTTATGCTTCCAAAAATGGATGGATTTGCTGTTTGTAGAAGAATTAGAGCTGAATCAGTAGTACCAATAATATTTTTA
ACCGCTCTAGAGGCTATTTCAGAGAGAGTCGCAGGCTTGGATTTAGGGGCTGATGATTACTTATCTAAACCATTTAGTCC
AAAAGAGTTAGAGGCTAGGATAGCTACTATTTTGAGAAGAATGGGCCCAAGTATATCGGTTACTGAAACCAAAGAAGTTC
CTTCAGGTAAAGGAGTTATGAAATTTGGAAGTTTAGTTGTTGATACTAATCGCAGACAAGTTTCTAGAGCTGGAGATAGA
ATTAGTCTAACTTATACTGAATTTAGTCTCCTAGAATTATTATTTGATGAGCCTGGGAAAGTTGTACCGCGAGCAGAAAT
ATTAGAACAGCTGTGGGGTTATCCTCCTCGTAGAGCTGCTGATTTAAGAGTTGTAGATGTATACGTTGCTAGATTAAGAG
GTAAGTTGGAACCAGATCCAAGAAATCCAGAATTAATATTAACTGTTAGAGGGATTGGTTACGCATCCCAGAGAGTTGGT
GAAACAGCAACATCTTTGGCAAGTTGA

Upstream 100 bases:

>100_bases
TATCTCTATGAGGGTTCGTAATGTTATATTTTTAATTGTTAGAATAAATATTCAATGCAATAGTTCTTTGCTTTGAAATA
TCGAGAAATCTTTTTTAACT

Downstream 100 bases:

>100_bases
GCCATAGTTTGATAATTTTATTAAATAAAACAAATATATTTAAATAAATTTTGTCTGAAATAAAAGAAGCACGCTTACAA
AAAGCTAGTTCACTCGTTAG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSKARILVVDDEPAVLKVLVTRLQLAGYQVYSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFL
TALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPSISVTETKEVPSGKGVMKFGSLVVDTNRRQVSRAGDR
ISLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
ETATSLAS

Sequences:

>Translated_248_residues
MSKARILVVDDEPAVLKVLVTRLQLAGYQVYSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFL
TALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPSISVTETKEVPSGKGVMKFGSLVVDTNRRQVSRAGDR
ISLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
ETATSLAS
>Mature_247_residues
SKARILVVDDEPAVLKVLVTRLQLAGYQVYSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFLT
ALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPSISVTETKEVPSGKGVMKFGSLVVDTNRRQVSRAGDRI
SLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVGE
TATSLAS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=41.991341991342, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.961038961039, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=37.9912663755458, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=37.6623376623377, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.0515021459227, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=36.3636363636364, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790860, Length=240, Percent_Identity=34.5833333333333, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=32.6271186440678, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=35.0649350649351, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=35.3448275862069, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.0952380952381, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.7586206896552, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.4763948497854, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=38.3177570093458, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=36.2068965517241, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=202, Percent_Identity=27.7227722772277, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27396; Mature: 27265

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKARILVVDDEPAVLKVLVTRLQLAGYQVYSATNGEEAIESFHRDSPDLIVLDVMLPKM
CCCCEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCC
DGFAVCRRIRAESVVPIIFLTALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
MGPSISVTETKEVPSGKGVMKFGSLVVDTNRRQVSRAGDRISLTYTEFSLLELLFDEPGK
HCCCCEEEECCCCCCCCCHHHHCCEEEECCHHHHHHCCCEEEEEEHHHHHHHHHHCCCCC
VVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHH
ETATSLAS
HHHHHHCC
>Mature Secondary Structure 
SKARILVVDDEPAVLKVLVTRLQLAGYQVYSATNGEEAIESFHRDSPDLIVLDVMLPKM
CCCEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCC
DGFAVCRRIRAESVVPIIFLTALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
MGPSISVTETKEVPSGKGVMKFGSLVVDTNRRQVSRAGDRISLTYTEFSLLELLFDEPGK
HCCCCEEEECCCCCCCCCHHHHCCEEEECCHHHHHHCCCEEEEEEHHHHHHHHHHCCCCC
VVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHH
ETATSLAS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]