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The map label for this gene is pheA [H]

Identifier: 126697033

GI number: 126697033

Start: 1428139

End: 1428984

Strand: Direct

Name: pheA [H]

Synonym: P9301_16951

Alternate gene names: 126697033

Gene position: 1428139-1428984 (Clockwise)

Preceding gene: 126697031

Following gene: 126697042

Centisome position: 86.98

GC content: 30.61

Gene sequence:

>846_bases
ATGCGCAAACAAGTTGCATATTTAGGTCCAAAAGGAACATACGCAGAAAAAGCAGCTCATATATTATCAAAGCTTGCCAA
TTTTCAGACACCTATATTTGTACCATGTAATGGGTTACATTCGGTCATTAAATCGTTAGCGTACAACATTTGTGATGCTG
CTGTAGTTCCTATAGAAAATTCCGTAGAAGGGGGCGTTACAGCCACTCTAGATTCCCTTTGGAAATTTCCTGAAATATTT
ATAAATAAAGCAATTGTTTTACCTATAAAACATGCATTAATTAGTGATGGTGAACTTTCAAATATTTCAGAAGTATTATC
TCATCCTCAAGCACTAGCTCAATGCTCAGAATGGTTATCTGAAAATCTTCCAAATGCAATACCTCTTCCAACAAATTCAA
CATCAGAAGCTGTCAATATGGTTAAGGGAAGTAAATTCAGAGCTGCTATCGGTTCAAAATCATTAATTCAAATTGAAGGA
CTTAAAGAATTAGCCTTTCCTATAAATGATGTTCCAGGTAATTGCACTAGATTTGTCTTATTAAGTAAGGAATCAAATTC
AAATTTAGCTAATATTGCTAGTTTCGCTTTCTCATTAATATCAAATAAACCTGGTGCTTTGCTTAAAGCAATAAATTATA
TTGCAGATTTTGGGTTTAATATGAGTAAGATTGAATCTAGACCTTCAAAAAGAGAACTAGGCGAATATATAATTTATATT
GATTTAGAAATAAATAATCAAAATAACATTGCAAATTTTCTTGAATTGAAAAATAAGCTAGAACCACTTTGTAATAATTT
AGTAGATTTTGGAAGTTATTTTTCTAAAAATATTGAACTAAATTAA

Upstream 100 bases:

>100_bases
GTGTTACAGAAAGCTTTAATTTCTGTTTAGCATCAAAAGACAATAGCATTTTCTATATTCCTCCAATGCTTATTTGATCA
CTTTTTTTTTAAGATTAATC

Downstream 100 bases:

>100_bases
TTTATCCTCTACATTTATAAACTCCAAACTCCATTAAACCTTTTCTAAATGCCCAGTTCATGAGAAGTATTGTTGGAATC
TCTCTAATCGACTTCAATAT

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRKQVAYLGPKGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYNICDAAVVPIENSVEGGVTATLDSLWKFPEIF
INKAIVLPIKHALISDGELSNISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSLIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
DLEINNQNNIANFLELKNKLEPLCNNLVDFGSYFSKNIELN

Sequences:

>Translated_281_residues
MRKQVAYLGPKGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYNICDAAVVPIENSVEGGVTATLDSLWKFPEIF
INKAIVLPIKHALISDGELSNISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSLIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
DLEINNQNNIANFLELKNKLEPLCNNLVDFGSYFSKNIELN
>Mature_281_residues
MRKQVAYLGPKGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYNICDAAVVPIENSVEGGVTATLDSLWKFPEIF
INKAIVLPIKHALISDGELSNISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSLIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
DLEINNQNNIANFLELKNKLEPLCNNLVDFGSYFSKNIELN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=282, Percent_Identity=29.4326241134752, Blast_Score=99, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324013, Length=319, Percent_Identity=28.2131661442006, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 30774; Mature: 30774

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKQVAYLGPKGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYNICDAAVVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCEEECCCC
SVEGGVTATLDSLWKFPEIFINKAIVLPIKHALISDGELSNISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHCCHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSLIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
EECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DLEINNQNNIANFLELKNKLEPLCNNLVDFGSYFSKNIELN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRKQVAYLGPKGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYNICDAAVVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCEEECCCC
SVEGGVTATLDSLWKFPEIFINKAIVLPIKHALISDGELSNISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHCCHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSLIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
EECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DLEINNQNNIANFLELKNKLEPLCNNLVDFGSYFSKNIELN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]