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The map label for this gene is rpoC1

Identifier: 126697013

GI number: 126697013

Start: 1404027

End: 1405931

Strand: Reverse

Name: rpoC1

Synonym: P9301_16751

Alternate gene names: 126697013

Gene position: 1405931-1404027 (Counterclockwise)

Preceding gene: 126697014

Following gene: 126697012

Centisome position: 85.63

GC content: 36.96

Gene sequence:

>1905_bases
ATGACAAACAGCAACTTAAGAACTGAAAATCACTTTGATTACGTCAAAATTTCAATAGCTTCTCCACAAAGAATAATGGA
TTGGGGGCAGAGGACATTGCCCAATGGACAAGTAGTTGGTGAAGTCACTAAACCAGAGACTATAAATTACAGGACACTTA
AACCGGAAATGGATGGGTTGTTTTGTGAAAAGATTTTTGGGCCATCAAAAGATTGGGAATGCCATTGTGGAAAGTACAAA
AGGGTAAGACATCGCGGCATTGTTTGTGAAAGATGTGGGGTTGAAGTGACTGAAAGTCGAGTCAGAAGACATAGGATGGG
ATATATAAAACTTGCTGCGCCAGTTTCCCATGTTTGGTATTTGAAAGGAATACCTAGTTATGTTGCGATACTCTTGGATA
TCCCTCTTAGAGATGTAGAGCAAATAGTTTATTTTAATTGTTATGTTGTTTTAGACCCGGGTGATCATAAAGAACTTAAA
TATAAGCAATTACTCACTGAGGATGAATGGCTGGAAATTGAAGATGAAATTTATGCTGAAGATTCAACTATCGAAAATGA
ACCTTTTGTTGGAATTGGTGCAGAGGCACTCAAGCAATTACTTGAGGACCTTGATTTAAATCAGGTTGCTGAGGAGCTTA
GAGAAGAAATTACTAACAGCAAAGGGCAAAAGAGGGCAAAACTTATAAAAAGGATAAGAGTTATTGATAATTTCATTGCA
ACCAATGCTAAACCAGAATGGATGGTATTAGATGCAATCCCAGTTATACCTCCTGATCTTAGACCTATGGTTCAGCTTGA
TGGAGGAAGATTCGCAACTTCAGATTTAAACGACTTATATAGAAGAGTTATAAATAGAAATAATAGACTGGCTAGGCTTC
AAGAAATTTTAGCTCCTGAAATTATCGTAAGAAACGAAAAAAGAATGCTTCAGGAGGCAGTTGATGCCCTTATAGATAAT
GGAAGGAGAGGAAGAACTGTTGTTGGAGCAAATAATAGGGCTCTTAAGTCCCTAAGTGACATAATTGAAGGAAAACAAGG
AAGATTTAGACAGAATCTTCTTGGAAAGCGTGTTGACTATTCAGGAAGATCCGTAATAGTTGTGGGTCCAAAATTAAAAA
TGCATCAGTGTGGTCTTCCAAAAGAAATGGCGATAGAGCTCTTTCAACCTTTCGTAATTCATAGATTAATTCGACAAAAT
ATTGTAAATAATATTAAAGCTGCAAAAAAATTAATACAAAAAGCTGATGACGAAGTTATGCAGGTACTTCAGGAAGTAAT
TGAAGGTCATCCAATTCTCTTGAATAGAGCCCCTACGCTGCATCGTTTAGGAATTCAAGCTTTTGAACCGAAATTAGTTG
GAGGTAGAGCAATACAACTTCATCCTTTAGTTTGTCCTGCATTCAATGCTGACTTCGATGGAGATCAAATGGCAGTACAT
GTTCCTTTAGCTTTAGAGGCACAAACTGAAGCACGCATGCTTATGTTGGCCAGTAATAATATTCTTTCTCCTGCTACCGG
GGAACCAATTGTGACTCCATCACAAGATATGGTTTTGGGATCTTATTATCTAACGGCTCTGCAACCGAATTATCAAAAAC
CAGAATTCGGAGATAATAAGACTACTTTTGCTTCATTAGAAGATGTTATTTTTGCTTTTGAAGATAAAAGACTCAGCCTA
CACGAATGGATTTGGGTTAGATTTAATGGAGAGGTTGAAGATGAAGACGAAATGCGTAGTCCACAAAAAACTCAATTGCT
AGAAGATAGTTCAAGACTAGAGATCTGGAATTTAAGAAGGGACAGATTTGACTCTGATAATAACTTAATAAGCAGATTTA
TACTGACAACTGTTGGGAGAGTGGTTATGAACTATACCATCATCGATTCTGTATCTAAAACGTAA

Upstream 100 bases:

>100_bases
AATACTCCATCAAGACCTACTTACGAATCTCTCGGAACCTCAGAATATGAGGAAGATTAAATATCAAATTGAAACCATTT
TTAATTTAAATTAGCCAAAA

Downstream 100 bases:

>100_bases
TCTTTAAAAACTATTTTCATTTACTTAAAAATCATGACTTCATCTAAACCTAAAAAAACATCCAGAGTACGTAAAACTAC
TAAAAACTCTAAAAAGAATA

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSL
HEWIWVRFNGEVEDEDEMRSPQKTQLLEDSSRLEIWNLRRDRFDSDNNLISRFILTTVGRVVMNYTIIDSVSKT

Sequences:

>Translated_634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSL
HEWIWVRFNGEVEDEDEMRSPQKTQLLEDSSRLEIWNLRRDRFDSDNNLISRFILTTVGRVVMNYTIIDSVSKT
>Mature_633_residues
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKY
KQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIAT
NAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVHV
PLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSLH
EWIWVRFNGEVEDEDEMRSPQKTQLLEDSSRLEIWNLRRDRFDSDNNLISRFILTTVGRVVMNYTIIDSVSKT

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily

Homologues:

Organism=Homo sapiens, GI4505939, Length=490, Percent_Identity=26.9387755102041, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI39725938, Length=321, Percent_Identity=28.9719626168224, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=31.6964285714286, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI2367335, Length=524, Percent_Identity=62.2137404580153, Blast_Score=693, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=32.1428571428571, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=30.8196721311475, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71998295, Length=347, Percent_Identity=24.4956772334294, Blast_Score=96, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320061, Length=498, Percent_Identity=27.5100401606426, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=235, Percent_Identity=35.3191489361702, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324917, Length=266, Percent_Identity=25.187969924812, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17530899, Length=310, Percent_Identity=29.6774193548387, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360912, Length=526, Percent_Identity=26.425855513308, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17647875, Length=337, Percent_Identity=28.1899109792285, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC1_PROM0 (A3PEX3)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091899.1
- ProteinModelPortal:   A3PEX3
- SMR:   A3PEX3
- STRING:   A3PEX3
- GeneID:   4912529
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_16751
- eggNOG:   COG0086
- HOGENOM:   HBG285548
- OMA:   HVWYLKG
- ProtClustDB:   PRK02625
- BioCyc:   PMAR167546:P9301ORF_1707-MONOMER
- HAMAP:   MF_01323
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755
- SMART:   SM00663
- TIGRFAMs:   TIGR02387

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3

EC number: =2.7.7.6

Molecular weight: Translated: 72595; Mature: 72463

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNK
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
TTFASLEDVIFAFEDKRLSLHEWIWVRFNGEVEDEDEMRSPQKTQLLEDSSRLEIWNLRR
CHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCHHHHHHCCCCCEEEEECHH
DRFDSDNNLISRFILTTVGRVVMNYTIIDSVSKT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNK
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
TTFASLEDVIFAFEDKRLSLHEWIWVRFNGEVEDEDEMRSPQKTQLLEDSSRLEIWNLRR
CHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCHHHHHHCCCCCEEEEECHH
DRFDSDNNLISRFILTTVGRVVMNYTIIDSVSKT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA