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The map label for this gene is queF

Identifier: 126696989

GI number: 126696989

Start: 1381301

End: 1381711

Strand: Reverse

Name: queF

Synonym: P9301_16511

Alternate gene names: 126696989

Gene position: 1381711-1381301 (Counterclockwise)

Preceding gene: 126696992

Following gene: 126696985

Centisome position: 84.15

GC content: 28.71

Gene sequence:

>411_bases
ATGAGTAAAGCTAAATTGGATGATTCTACGCAAAGACCACTTTATGGTGAAAGAATTATTGAAGAATCAAAAATAATTTG
TTTCGATAATCCAAATAAAAAAAGAATTTATGAAATTTCTATTCAGTTACCTGAATTTACATGTAAGTGCCCCTTTTCTG
GTTATCCAGATTTTGCAAAGCTAAGTATTATTTATCAACCTAATTTGAAAGTATATGAGTTGAAGTCTTTAAAGCTTTAT
ATTAATAGTTTTAGAGATATAAAAATATCACATGAAGAGGTTGTAAATAGAATTATGGATGATTTAGTGAATGAGGGCTC
GCCTCACTGGATACATTTAAATGCTGCATTTAACCCTAGAGGGAATGTTTCAATGCAGTTAGATATTTTTAGTGGACAGA
AAAAAAATTAA

Upstream 100 bases:

>100_bases
TAATAGCTTTTGACTTATTCAATTGTAATACTTAAGCTTGTTGAGAATTTTGCAGATTTTGATCTTTTTATATAGGTTTA
ATAAATAAGTTCTACTAAAG

Downstream 100 bases:

>100_bases
AAATTTTTTATTTCTTCTGATAATTTAAAAAATTCTTTTTTAAACCCAACTAGATTTTTATTGCTAAGACCTCCAATGGA
TAAACTTTGTGATTCTTGAT

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSKAKLDDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAKLSIIYQPNLKVYELKSLKLY
INSFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPRGNVSMQLDIFSGQKKN

Sequences:

>Translated_136_residues
MSKAKLDDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAKLSIIYQPNLKVYELKSLKLY
INSFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPRGNVSMQLDIFSGQKKN
>Mature_135_residues
SKAKLDDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAKLSIIYQPNLKVYELKSLKLYI
NSFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPRGNVSMQLDIFSGQKKN

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_PROM0 (A3PEU9)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091875.1
- ProteinModelPortal:   A3PEU9
- SMR:   A3PEU9
- STRING:   A3PEU9
- GeneID:   4911000
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_16511
- eggNOG:   COG0780
- HOGENOM:   HBG294103
- OMA:   FRNAGIF
- ProtClustDB:   PRK13258
- BioCyc:   PMAR167546:P9301ORF_1682-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 15827; Mature: 15696

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAKLDDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAK
CCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEEEECCCEEEECCCCCCCCCEE
LSIIYQPNLKVYELKSLKLYINSFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPR
EEEEECCCCEEEEEEEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GNVSMQLDIFSGQKKN
CCEEEEEEECCCCCCC
>Mature Secondary Structure 
SKAKLDDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAK
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEEEECCCEEEECCCCCCCCCEE
LSIIYQPNLKVYELKSLKLYINSFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPR
EEEEECCCCEEEEEEEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GNVSMQLDIFSGQKKN
CCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA