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The map label for this gene is galE [H]

Identifier: 126696762

GI number: 126696762

Start: 1191331

End: 1192389

Strand: Direct

Name: galE [H]

Synonym: P9301_14241

Alternate gene names: 126696762

Gene position: 1191331-1192389 (Clockwise)

Preceding gene: 126696757

Following gene: 126696765

Centisome position: 72.56

GC content: 29.27

Gene sequence:

>1059_bases
GTGAATAAAATAATTCTTGTCACTGGCGGTGCTGGCTTTATTGGAAGTCATACATGTTTGCTACTTTTAGAATCTGGATA
CAAGGTAGTAGTAATTGATTCCTTTATAAACAGTTCTTTGAATTCATTAGAAAGAGTTAAAAAAATTCTTATTAGTGATA
ACAATTTTTTTTCAAATAGATTAAAAATAGTAAAAGGAGATTTACGTGATTTTGAATGCATAAACAATATCTTTTTAAAA
TACAAGATTAACAAAGAAAAAATTGATGGGGTAATTCATTTCGCAGGTTTAAAAAACATTAAAGAATCCATATCTGATCC
TATTTCATATTGGGAAAATAATGTAACTGGAACTATAAATCTTTTGAAAGCTATGCATCATAACAATTGTAATTCAATTA
TATTTAGTAGCACTGCAGCATTATATGGTAAATCTGAGTCAAAGGTATTTAAAGAAACTTCTATAAAATCACCCATAAAT
CCATATGGAGAAACAAAGTTAGCGATTGAGAAATTGCTTAATGATCTTTATAAAAGCAACCCAAATTCTTGGAAAATAGC
CAATTTACGATACTTTAATCCAATTGGTTGTCATAACTCAGGCCAGATAGGAGAAAGCCCTTTAAATAAACCAACTAATA
TTTTCCCCTTAATTATCAAAGCCGCTTCAAAAGAAATAAAAAAAATTTCTATATTTGGAAATGACTGGCCTACTCATGAT
GGCACTGGAATTAGAGACTACATACATGTAATGGATCTTGCTGAAGGGCATATCAAAGCAATTGAATTTTTAATGTCAAA
AAATAAAGGGAATTTAATTAATTTAAATCTTGGTAGGGGTGTAGGAGTTTCAGTTCTTGAATTAATTAATACGTTTACCA
AAGTAAATAATGTAAATATTGAATATGAATTTGCTGAAAGAAGAGAGGGTGATGTACCTATTTCAATCGCAGATAATTGT
CTTGCCAAAACACTATTAAATTGGTGCCCTAAGAGAGATATTGAAGAAATGTGTATTGATGGATGGAAATGGAAACTATT
AAATCCGAAAGGATATTAA

Upstream 100 bases:

>100_bases
TGAGTGGAATTATAGGTTTCATTAATGAATTAAAAATTTTTAATCCTAAAGATAATACTATAAACTAGTGAGACAGATTA
TTTATTAATTTTGAAATAGA

Downstream 100 bases:

>100_bases
ATTATGAAAAACTAAAAATAATTAAACTTTTCAAAAAAACTTTAAGCTTAATTTATCAATAAGTTTAATTTCTCTGTCTA
AAACTTTGGCTGAATCGTAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNKIILVTGGAGFIGSHTCLLLLESGYKVVVIDSFINSSLNSLERVKKILISDNNFFSNRLKIVKGDLRDFECINNIFLK
YKINKEKIDGVIHFAGLKNIKESISDPISYWENNVTGTINLLKAMHHNNCNSIIFSSTAALYGKSESKVFKETSIKSPIN
PYGETKLAIEKLLNDLYKSNPNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHD
GTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNIEYEFAERREGDVPISIADNC
LAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY

Sequences:

>Translated_352_residues
MNKIILVTGGAGFIGSHTCLLLLESGYKVVVIDSFINSSLNSLERVKKILISDNNFFSNRLKIVKGDLRDFECINNIFLK
YKINKEKIDGVIHFAGLKNIKESISDPISYWENNVTGTINLLKAMHHNNCNSIIFSSTAALYGKSESKVFKETSIKSPIN
PYGETKLAIEKLLNDLYKSNPNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHD
GTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNIEYEFAERREGDVPISIADNC
LAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY
>Mature_352_residues
MNKIILVTGGAGFIGSHTCLLLLESGYKVVVIDSFINSSLNSLERVKKILISDNNFFSNRLKIVKGDLRDFECINNIFLK
YKINKEKIDGVIHFAGLKNIKESISDPISYWENNVTGTINLLKAMHHNNCNSIIFSSTAALYGKSESKVFKETSIKSPIN
PYGETKLAIEKLLNDLYKSNPNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHD
GTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNIEYEFAERREGDVPISIADNC
LAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=359, Percent_Identity=40.3899721448468, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI56118217, Length=359, Percent_Identity=40.3899721448468, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI189083684, Length=359, Percent_Identity=40.3899721448468, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI7657641, Length=289, Percent_Identity=28.3737024221453, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=349, Percent_Identity=44.1260744985673, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788353, Length=381, Percent_Identity=26.509186351706, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994969, Length=369, Percent_Identity=25.4742547425474, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=358, Percent_Identity=39.3854748603352, Blast_Score=258, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71982038, Length=360, Percent_Identity=39.1666666666667, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17539532, Length=339, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=357, Percent_Identity=43.4173669467787, Blast_Score=289, Evalue=5e-79,
Organism=Drosophila melanogaster, GI19923002, Length=355, Percent_Identity=41.9718309859155, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI21356223, Length=344, Percent_Identity=25, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 39568; Mature: 39568

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIILVTGGAGFIGSHTCLLLLESGYKVVVIDSFINSSLNSLERVKKILISDNNFFSNR
CCEEEEEECCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKIVKGDLRDFECINNIFLKYKINKEKIDGVIHFAGLKNIKESISDPISYWENNVTGTIN
CEEEECCCHHHHHHCCEEEEEEECHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
LLKAMHHNNCNSIIFSSTAALYGKSESKVFKETSIKSPINPYGETKLAIEKLLNDLYKSN
HHHHHHCCCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
PNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHD
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCC
GTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNI
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEE
EYEFAERREGDVPISIADNCLAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY
EEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MNKIILVTGGAGFIGSHTCLLLLESGYKVVVIDSFINSSLNSLERVKKILISDNNFFSNR
CCEEEEEECCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKIVKGDLRDFECINNIFLKYKINKEKIDGVIHFAGLKNIKESISDPISYWENNVTGTIN
CEEEECCCHHHHHHCCEEEEEEECHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
LLKAMHHNNCNSIIFSSTAALYGKSESKVFKETSIKSPINPYGETKLAIEKLLNDLYKSN
HHHHHHCCCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
PNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHD
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCC
GTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNI
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEE
EYEFAERREGDVPISIADNCLAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY
EEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]