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The map label for this gene is gap3 [H]

Identifier: 126696574

GI number: 126696574

Start: 1048311

End: 1049333

Strand: Direct

Name: gap3 [H]

Synonym: P9301_12361

Alternate gene names: 126696574

Gene position: 1048311-1049333 (Clockwise)

Preceding gene: 126696572

Following gene: 126696575

Centisome position: 63.85

GC content: 33.04

Gene sequence:

>1023_bases
ATGAAAATTGGAATTAATGGTTTTGGAAGAATTGGCAGATTAGTTTTCAGAGCATTATGGGATAGAGCTGATATAGAAAT
AACTCATATAAATGAGATAGCAGGAGATTCGAATGCTGCTGCGCATTTACTCGAATTCGATTCAGTCCATGGTAGATGGG
TGAAAGATATAAAGGTAAAAGAAGAAGAAATAATAATTGATGGAAAGAAATTAACCTACACATCTTTTAAAAATTACCTT
GATATTCCTTGGGAAAAATCTTCTGTAGATATTATTTTGGAATGTACAGGAAAGAATAAAAAGCCAGACAAACTAAATCC
CTATTTTGATACTCTTGGGATGAAAAGAGTAATAGTAGCTTGTCCAGTCAAAGGAATTGTTGCAGAAGCTGAATCACTGA
ATATTGTTTACGGTATAAATCAAAGTCTTTATGACCCTACCAAACATAAATTAGTAACTGCAGCATCCTGCACTACAAAT
TGTTTAGCTCCGATAGTAAAGGTAATTAATGAAAATTTTTCTATTAAACACGGTGCTATTACAACTATTCACGATGTAAC
GAACACTCAAGTTCCTGTAGATTTTTATAAAAGTGATCTGAGGAGAGCAAGAGGATGTATGCAAAGTTTAATACCTACTA
CCACTGGATCTGCTAAAGCTATCGCTGAGATCTTTCCAGAATTAAAAGGAAAATTAAATGGACATGCAGTAAGAGTTCCT
CTACTTAATGGTTCTTTAACAGATGCAGTTTTTGAATTAAATAAAGAAGTGACAACTGAACAAGTGAATATGGCACTAAA
GGAAGCTTCAGAAACTTATTTAAAAGGAATTCTTGGCTACGAAGAAAGACCTTTAGTTTCTGCAGATTATGTAAATGACT
CTAGAAGTTCAATAGTTGATAGTTTATCAACGATGGTTGTTAATTCAAATTTATTAAAGATATACGCTTGGTATGACAAC
GAGTGGGGTTACAGCTGCAGACTTGCAGATCTTACTGAATATGTAATCAAAAAAGAGATTTAA

Upstream 100 bases:

>100_bases
TCCCTAAATATAGCTTAAATAAAAAAGATTTCATTAATCAAAACAACTTGATACATCAAAATATTTTGATCTATAATTAA
TATAGAAAATTTCAACAGTG

Downstream 100 bases:

>100_bases
TTTATGTCTTTATGAAGTTATCTAATATTCAACAATATAGTGTTGTAACAGCAAACTATTGGGCGTTCACGCTTACTGAC
GGCGCATTAAGATTATTAGT

Product: putative glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWVKDIKVKEEEIIIDGKKLTYTSFKNYL
DIPWEKSSVDIILECTGKNKKPDKLNPYFDTLGMKRVIVACPVKGIVAEAESLNIVYGINQSLYDPTKHKLVTAASCTTN
CLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELKGKLNGHAVRVP
LLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNSNLLKIYAWYDN
EWGYSCRLADLTEYVIKKEI

Sequences:

>Translated_340_residues
MKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWVKDIKVKEEEIIIDGKKLTYTSFKNYL
DIPWEKSSVDIILECTGKNKKPDKLNPYFDTLGMKRVIVACPVKGIVAEAESLNIVYGINQSLYDPTKHKLVTAASCTTN
CLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELKGKLNGHAVRVP
LLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNSNLLKIYAWYDN
EWGYSCRLADLTEYVIKKEI
>Mature_340_residues
MKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWVKDIKVKEEEIIIDGKKLTYTSFKNYL
DIPWEKSSVDIILECTGKNKKPDKLNPYFDTLGMKRVIVACPVKGIVAEAESLNIVYGINQSLYDPTKHKLVTAASCTTN
CLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELKGKLNGHAVRVP
LLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNSNLLKIYAWYDN
EWGYSCRLADLTEYVIKKEI

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=39.1176470588235, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI7657116, Length=340, Percent_Identity=35.5882352941176, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=41.4201183431953, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=35.8208955223881, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=38.0116959064327, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=38.0116959064327, Blast_Score=243, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=38.3040935672515, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=38.0116959064327, Blast_Score=241, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6322409, Length=338, Percent_Identity=40.5325443786982, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=338, Percent_Identity=40.2366863905325, Blast_Score=271, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6322468, Length=338, Percent_Identity=39.0532544378698, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI85725000, Length=339, Percent_Identity=40.4129793510324, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI22023983, Length=339, Percent_Identity=40.4129793510324, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17933600, Length=339, Percent_Identity=40.117994100295, Blast_Score=254, Evalue=6e-68,
Organism=Drosophila melanogaster, GI18110149, Length=339, Percent_Identity=40.117994100295, Blast_Score=254, Evalue=6e-68,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=38.4384384384384, Blast_Score=245, Evalue=4e-65,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37950; Mature: 37950

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWVKDIKVK
CEECCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCCCCCEEEEEEEC
EEEIIIDGKKLTYTSFKNYLDIPWEKSSVDIILECTGKNKKPDKLNPYFDTLGMKRVIVA
CCEEEEECCEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCHHHEEEE
CPVKGIVAEAESLNIVYGINQSLYDPTKHKLVTAASCTTNCLAPIVKVINENFSIKHGAI
CCCHHHHCCCCCEEEEEECCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHCCCCCEECCCE
TTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELKGKLNGHAVRVP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
LLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHH
SLSTMVVNSNLLKIYAWYDNEWGYSCRLADLTEYVIKKEI
HHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWVKDIKVK
CEECCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCCCCCEEEEEEEC
EEEIIIDGKKLTYTSFKNYLDIPWEKSSVDIILECTGKNKKPDKLNPYFDTLGMKRVIVA
CCEEEEECCEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCHHHEEEE
CPVKGIVAEAESLNIVYGINQSLYDPTKHKLVTAASCTTNCLAPIVKVINENFSIKHGAI
CCCHHHHCCCCCEEEEEECCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHCCCCCEECCCE
TTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELKGKLNGHAVRVP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
LLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHH
SLSTMVVNSNLLKIYAWYDNEWGYSCRLADLTEYVIKKEI
HHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]