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The map label for this gene is pilD [H]

Identifier: 126696026

GI number: 126696026

Start: 610596

End: 611399

Strand: Direct

Name: pilD [H]

Synonym: P9301_06881

Alternate gene names: 126696026

Gene position: 610596-611399 (Clockwise)

Preceding gene: 126696018

Following gene: 126696030

Centisome position: 37.19

GC content: 26.12

Gene sequence:

>804_bases
GTGGAAATAATATTGATATATTTGTTTGTAATTGGTTGTTGTATAGGAAGCTTTGTAAATGTAGTAATTTATAGATTACC
TTTAAATCAATCAATAGTTTATCCCAATAGTAGATGTCCGAAATGTAATTCAAGAATTAAATGGTTTGATAATATACCAA
TAATAAGTTGGCTTTTATTAAGAGGTAAATGCAGAGCTTGTAAGAATAAAATAGCTTTTTTTTACCCTAGTATTGAATTA
TTTATAGGCATTTTATTTTGTCTTAATCTATACTCTCAGCCAACAATTTATAGTCAACAACCTACAAATTTAATTATATT
TTTGGGATGTATTTTTAGTGTAATTTTATTTACCTTAGCAATATTAGATTTTAAATATTTTTGGCTTCCGCAAGTTCTTA
CTTCAGGAGGTTTTGTTTCAGGAATAATTACCTCTTTATATATTGATCTTAGCAATGATCTCTATCAATTTAATTATGTA
ATTTATACATTACTTGCTTCTTTATTAGGTTTTACATTTTTTAATTTATTAAGTCGTATAGGTAAAAAAATTTATAATAA
ACCCGTAATTGGAGGAGGGGATGCGAAACTAGGTGCCATGATTGGTTCTTGGTTAGGTATACAGGGATTATTTATATCTA
TATGGTTAGCATTTATATCGGCTGGTATTTTTGTGATTGTAGGTTTAATTTTTAAAAAAATAAAAAGGAATCAAAAAATA
CCTTTTGGGATTTTTTTAGCTTTGTCTGGATTGCTTGTTTGGTACTTTGGCAATGAGATATTTTTAGATATATTATTTTT
ATAA

Upstream 100 bases:

>100_bases
AAACATCAGTTGAGACATTAATTTGTTATTTACAAATAAAAATAGTAGAATTTTTTGAGTTTATTTCTAAAGCTTTCAGC
TTCACTATAAGGATTATCAA

Downstream 100 bases:

>100_bases
ATTATACAAGGATTTACCCCACAGTAGACATCATACTGAACATAGGTAAATACATAGCAATTAGAATGATTCCTACAAAA
ACAGCTACGAATATAATCAT

Product: leader peptidase (prepilin peptidase) / N-methyltransferase

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MEIILIYLFVIGCCIGSFVNVVIYRLPLNQSIVYPNSRCPKCNSRIKWFDNIPIISWLLLRGKCRACKNKIAFFYPSIEL
FIGILFCLNLYSQPTIYSQQPTNLIIFLGCIFSVILFTLAILDFKYFWLPQVLTSGGFVSGIITSLYIDLSNDLYQFNYV
IYTLLASLLGFTFFNLLSRIGKKIYNKPVIGGGDAKLGAMIGSWLGIQGLFISIWLAFISAGIFVIVGLIFKKIKRNQKI
PFGIFLALSGLLVWYFGNEIFLDILFL

Sequences:

>Translated_267_residues
MEIILIYLFVIGCCIGSFVNVVIYRLPLNQSIVYPNSRCPKCNSRIKWFDNIPIISWLLLRGKCRACKNKIAFFYPSIEL
FIGILFCLNLYSQPTIYSQQPTNLIIFLGCIFSVILFTLAILDFKYFWLPQVLTSGGFVSGIITSLYIDLSNDLYQFNYV
IYTLLASLLGFTFFNLLSRIGKKIYNKPVIGGGDAKLGAMIGSWLGIQGLFISIWLAFISAGIFVIVGLIFKKIKRNQKI
PFGIFLALSGLLVWYFGNEIFLDILFL
>Mature_267_residues
MEIILIYLFVIGCCIGSFVNVVIYRLPLNQSIVYPNSRCPKCNSRIKWFDNIPIISWLLLRGKCRACKNKIAFFYPSIEL
FIGILFCLNLYSQPTIYSQQPTNLIIFLGCIFSVILFTLAILDFKYFWLPQVLTSGGFVSGIITSLYIDLSNDLYQFNYV
IYTLLASLLGFTFFNLLSRIGKKIYNKPVIGGGDAKLGAMIGSWLGIQGLFISIWLAFISAGIFVIVGLIFKKIKRNQKI
PFGIFLALSGLLVWYFGNEIFLDILFL

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=265, Percent_Identity=31.3207547169811, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 30329; Mature: 30329

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA