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The map label for this gene is spoVD [H]

Identifier: 126695882

GI number: 126695882

Start: 473355

End: 475106

Strand: Direct

Name: spoVD [H]

Synonym: P9301_05441

Alternate gene names: 126695882

Gene position: 473355-475106 (Clockwise)

Preceding gene: 126695881

Following gene: 126695883

Centisome position: 28.83

GC content: 33.05

Gene sequence:

>1752_bases
ATGAAAAAATACAAAAAAATTGTTCGTCTAATTCCCCTTGATCAAAGAAGATTTAAATTTCTCTATATTTTTAGCTTACT
GTTAATTTTTTGTTTGTTTGGTAGGTTAGTTAAATTGCAAGTCTTTAACGCCTCTGATTTGCAAAGGAAAGCTAGATTAA
TACAATCTTCTAAAACTAACTCCTTAAAAAAAAGGAGATCAATCGTTGATAGAAATAATAGAGTAATTGCCTACGATAAA
CCGCTCTATAAATTATGGGCCCATCCAAAATATTTTAATTTTCCTGGTGATTCAATTAACAGAGTTCGCAGTATTGAAGA
AGTTACAGAAAAATTGTCACCTATATTGGGTATTAATGATGAAATACTCTTGAGGAAATTTAATAATAAAATGAGTGGTA
TCAAACTTTTGGATAAAATTGCGGAAGAAAAGGCAGAAGAAATCAAGAACCTTCAAATAAGCGGAATTGATTTGTTTAAA
TATTCTCAGAGATATTATCCACAAGGGGAACTTTACTCTAATATTGTCGGTTTTGTTAATGATGAGAATGTAGCTTCAGC
AGGTTTAGAACTACATTTAGATAATCAAATTAAAGTTTTCAATAAAAGTAATTTAATAAAAAGAGGAGGAGATGGAACTC
CTCTACCGGATAATTCAGCACCAGGTGATTTTATTTCTGATTACAAAAGTTTAGGCCTAACTATAGATTCAAGATTGCAG
AAAGCTTCATACAATGCTTTATCAAAGCAAATAAGCAAATGGAAAGCAAAGAAGGGATTTGCAATAGTTATGGATGTTAA
TGATGGTCGGATTCTCTCTTTGGTTACAGTCCCATCATATGATCCAAATAAATTTTGGCAGTATGATTCTGAACTCTTTA
GGGGGTGGTATTCTCAAGATTTATTTGAGCCAGGCTCAACTTTTAAACCTATTAATCTTGCCTTAGCTTTAGAAGAAAAA
GTCATCCAGAGAGATGGAGTAGTTGAAGATACTGGAGAGATTAATGTTGGAGGATGGACACTTTCTAATTGGGATAAAAA
AGGTAATGGATACATTGACTATCCAAAAGTTTTGCAGGTTTCAAGTAATGTTGCGATGGTAAAAATAATGCAAAATTTAG
ACCCCACAATTTATTGGGATTGGCTAAAAAATTTAGGTATAAATAAAAATTTAGAGACTGACTTATTTGAATCAACTGCT
GGCCAACTTAAGAGAAAAGATTTATTTGTAAATCAATCAATTGAGCCTGCTGTCACTTCTTTTGGTAAAGGTTTCTCAAT
CTCGCCACTTAAATTGATTCAACTTCATGCGGCTCTTGCAAATGGAGGTTTTGAAGTGACGCCTCATGTGACCTCAACTT
TCAAAGAAAGATTTAATAAAAATCCAAAAAAACAATTTTTTTCAGGCGAGGTTACTAAAACTGTTCTTGAATGGATGGAG
AGCGTAGTCGATAAAGGAAGTGGATCTGGAGTAAAAATCGAAGGTTATAGGATAGCGGGGAAAACGGGCACTTCTCAAAA
AGCCTTAAATGGTTCGTATACAAGCAAAAAAGTTTGTAGTTTTGTCGCAACCTTACCAGTTAATGATCCAAAATATGCTG
TCCTTGTAGTCGTTGATGAGCCATCTAAATCATATGCATATGGTTCAACTGTTGCAGTACCAGTTGCGAAAGAAATTATC
GAGACTTTGATAGTAATTGAAAAAATACCTCCTAAGATTAAAGATCATGGAATGATTGTTAAAAAACCCTAA

Upstream 100 bases:

>100_bases
ATATAGATAAACTTACTGAAAAAAAAGAAAGTACATTTAAGAAAAATTTAAATACCTTCATTGAAGGTTTTAGTGATAGC
AAATATCAGAGGGGATATTG

Downstream 100 bases:

>100_bases
AATTTTCCAATTTTATAAATTTTTAATTCACTATCTGATGAATTCATGAGGAATTAAAGCTAGTTTGTATATATATGACT
ACCTAGACATGAAATCAATT

Product: peptidoglycan synthetase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKYKKIVRLIPLDQRRFKFLYIFSLLLIFCLFGRLVKLQVFNASDLQRKARLIQSSKTNSLKKRRSIVDRNNRVIAYDK
PLYKLWAHPKYFNFPGDSINRVRSIEEVTEKLSPILGINDEILLRKFNNKMSGIKLLDKIAEEKAEEIKNLQISGIDLFK
YSQRYYPQGELYSNIVGFVNDENVASAGLELHLDNQIKVFNKSNLIKRGGDGTPLPDNSAPGDFISDYKSLGLTIDSRLQ
KASYNALSKQISKWKAKKGFAIVMDVNDGRILSLVTVPSYDPNKFWQYDSELFRGWYSQDLFEPGSTFKPINLALALEEK
VIQRDGVVEDTGEINVGGWTLSNWDKKGNGYIDYPKVLQVSSNVAMVKIMQNLDPTIYWDWLKNLGINKNLETDLFESTA
GQLKRKDLFVNQSIEPAVTSFGKGFSISPLKLIQLHAALANGGFEVTPHVTSTFKERFNKNPKKQFFSGEVTKTVLEWME
SVVDKGSGSGVKIEGYRIAGKTGTSQKALNGSYTSKKVCSFVATLPVNDPKYAVLVVVDEPSKSYAYGSTVAVPVAKEII
ETLIVIEKIPPKIKDHGMIVKKP

Sequences:

>Translated_583_residues
MKKYKKIVRLIPLDQRRFKFLYIFSLLLIFCLFGRLVKLQVFNASDLQRKARLIQSSKTNSLKKRRSIVDRNNRVIAYDK
PLYKLWAHPKYFNFPGDSINRVRSIEEVTEKLSPILGINDEILLRKFNNKMSGIKLLDKIAEEKAEEIKNLQISGIDLFK
YSQRYYPQGELYSNIVGFVNDENVASAGLELHLDNQIKVFNKSNLIKRGGDGTPLPDNSAPGDFISDYKSLGLTIDSRLQ
KASYNALSKQISKWKAKKGFAIVMDVNDGRILSLVTVPSYDPNKFWQYDSELFRGWYSQDLFEPGSTFKPINLALALEEK
VIQRDGVVEDTGEINVGGWTLSNWDKKGNGYIDYPKVLQVSSNVAMVKIMQNLDPTIYWDWLKNLGINKNLETDLFESTA
GQLKRKDLFVNQSIEPAVTSFGKGFSISPLKLIQLHAALANGGFEVTPHVTSTFKERFNKNPKKQFFSGEVTKTVLEWME
SVVDKGSGSGVKIEGYRIAGKTGTSQKALNGSYTSKKVCSFVATLPVNDPKYAVLVVVDEPSKSYAYGSTVAVPVAKEII
ETLIVIEKIPPKIKDHGMIVKKP
>Mature_583_residues
MKKYKKIVRLIPLDQRRFKFLYIFSLLLIFCLFGRLVKLQVFNASDLQRKARLIQSSKTNSLKKRRSIVDRNNRVIAYDK
PLYKLWAHPKYFNFPGDSINRVRSIEEVTEKLSPILGINDEILLRKFNNKMSGIKLLDKIAEEKAEEIKNLQISGIDLFK
YSQRYYPQGELYSNIVGFVNDENVASAGLELHLDNQIKVFNKSNLIKRGGDGTPLPDNSAPGDFISDYKSLGLTIDSRLQ
KASYNALSKQISKWKAKKGFAIVMDVNDGRILSLVTVPSYDPNKFWQYDSELFRGWYSQDLFEPGSTFKPINLALALEEK
VIQRDGVVEDTGEINVGGWTLSNWDKKGNGYIDYPKVLQVSSNVAMVKIMQNLDPTIYWDWLKNLGINKNLETDLFESTA
GQLKRKDLFVNQSIEPAVTSFGKGFSISPLKLIQLHAALANGGFEVTPHVTSTFKERFNKNPKKQFFSGEVTKTVLEWME
SVVDKGSGSGVKIEGYRIAGKTGTSQKALNGSYTSKKVCSFVATLPVNDPKYAVLVVVDEPSKSYAYGSTVAVPVAKEII
ETLIVIEKIPPKIKDHGMIVKKP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=567, Percent_Identity=29.2768959435626, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1786854, Length=597, Percent_Identity=22.1105527638191, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65789; Mature: 65789

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYKKIVRLIPLDQRRFKFLYIFSLLLIFCLFGRLVKLQVFNASDLQRKARLIQSSKTN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHCCCHH
SLKKRRSIVDRNNRVIAYDKPLYKLWAHPKYFNFPGDSINRVRSIEEVTEKLSPILGIND
HHHHHHHHHCCCCEEEEECCCHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
EILLRKFNNKMSGIKLLDKIAEEKAEEIKNLQISGIDLFKYSQRYYPQGELYSNIVGFVN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEECCEEHHHHHHHCCCCHHHHHHHHCCCC
DENVASAGLELHLDNQIKVFNKSNLIKRGGDGTPLPDNSAPGDFISDYKSLGLTIDSRLQ
CCCHHHCCEEEEECCEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KASYNALSKQISKWKAKKGFAIVMDVNDGRILSLVTVPSYDPNKFWQYDSELFRGWYSQD
HHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LFEPGSTFKPINLALALEEKVIQRDGVVEDTGEINVGGWTLSNWDKKGNGYIDYPKVLQV
HCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCEEECCCCCCCCCCCCCCHHEEE
SSNVAMVKIMQNLDPTIYWDWLKNLGINKNLETDLFESTAGQLKRKDLFVNQSIEPAVTS
CCCHHHHHHHHHCCCCEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHH
FGKGFSISPLKLIQLHAALANGGFEVTPHVTSTFKERFNKNPKKQFFSGEVTKTVLEWME
CCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
SVVDKGSGSGVKIEGYRIAGKTGTSQKALNGSYTSKKVCSFVATLPVNDPKYAVLVVVDE
HHHCCCCCCCEEEEEEEEECCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEC
PSKSYAYGSTVAVPVAKEIIETLIVIEKIPPKIKDHGMIVKKP
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MKKYKKIVRLIPLDQRRFKFLYIFSLLLIFCLFGRLVKLQVFNASDLQRKARLIQSSKTN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHCCCHH
SLKKRRSIVDRNNRVIAYDKPLYKLWAHPKYFNFPGDSINRVRSIEEVTEKLSPILGIND
HHHHHHHHHCCCCEEEEECCCHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
EILLRKFNNKMSGIKLLDKIAEEKAEEIKNLQISGIDLFKYSQRYYPQGELYSNIVGFVN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEECCEEHHHHHHHCCCCHHHHHHHHCCCC
DENVASAGLELHLDNQIKVFNKSNLIKRGGDGTPLPDNSAPGDFISDYKSLGLTIDSRLQ
CCCHHHCCEEEEECCEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KASYNALSKQISKWKAKKGFAIVMDVNDGRILSLVTVPSYDPNKFWQYDSELFRGWYSQD
HHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LFEPGSTFKPINLALALEEKVIQRDGVVEDTGEINVGGWTLSNWDKKGNGYIDYPKVLQV
HCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCEEECCCCCCCCCCCCCCHHEEE
SSNVAMVKIMQNLDPTIYWDWLKNLGINKNLETDLFESTAGQLKRKDLFVNQSIEPAVTS
CCCHHHHHHHHHCCCCEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHH
FGKGFSISPLKLIQLHAALANGGFEVTPHVTSTFKERFNKNPKKQFFSGEVTKTVLEWME
CCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
SVVDKGSGSGVKIEGYRIAGKTGTSQKALNGSYTSKKVCSFVATLPVNDPKYAVLVVVDE
HHHCCCCCCCEEEEEEEEECCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEC
PSKSYAYGSTVAVPVAKEIIETLIVIEKIPPKIKDHGMIVKKP
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]