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The map label for this gene is trpB

Identifier: 126695522

GI number: 126695522

Start: 170284

End: 171528

Strand: Reverse

Name: trpB

Synonym: P9301_01841

Alternate gene names: 126695522

Gene position: 171528-170284 (Counterclockwise)

Preceding gene: 126695525

Following gene: 126695520

Centisome position: 10.45

GC content: 37.99

Gene sequence:

>1245_bases
GTGGTAAGTACATTTTCTCGCAAAGATCAGAATTATAAAAATGACGATTTAAATCAACCCTCTAAAGAGGGAAGATTTGG
AAAATATGGTGGTCAATATGTTCCTGAAACGCTAATGCCTGCTCTTTTTGAGCTTGAAACAGCTGCATCTAATGCATGGA
AAGATAAACTTTTTGTAGAAGAATTAAATCATCTCCTTAAGACTTATGTAGGAAGAGAAACACCACTTTATGAAGCCAAA
AGACTTACTGAACATTACAAAACTAAACAAGCAACCCCTAGAATATGGCTTAAAAGGGAAGATTTAAATCATACTGGGGC
TCACAAAATTAATAATGCCCTCGGACAAGCTTTACTTGCAATAAGAATGGGCAAAAAAAGAATAATTGCAGAAACTGGAG
CAGGTCAGCACGGAGTTGCTACGGCTACTGTTTGTGCGAGATTTGGCTTGAAATGTATTATCTACATGGGTGCTGAAGAT
ATAAAAAGGCAATCCCTTAACGTTTTCAGAATGAAACTTCTAGGAGCTGAAGTTAAAGTTGTAAATTCTGGAACTGCAAC
ACTTAAGGATGCCACTAGTGAAGCCATTAGAGATTGGGTTTCTAATGTCGAAACCACACACTACATTTTAGGATCTGTTG
CCGGCCCACACCCTTTCCCAAAGATTGTGCGAGATTTTCATGCAGTTATAGGTGAAGAAACTAAAAAACAATGTTTAGAA
TCATTTGGCTCTTTTCCCGATATTTTGCTTGCTTGTGTAGGTGGGGGATCAAATGCAATGGGGCTTTTCCATCCTTTTGT
TAAAGAAACTTCTGTGCGTCTTATTGGAGTTGAAGCCGCAGGAAGCGGAGTTGATACTGACAAACATGCTGCCACAATCA
CTAAAGGTTCAGTTGGAATTTTGCATGGATCAATGAGTCTTCTCTTGCAAGATGATAATGGTCAAGTACAAGAAGCTCAC
TCAATAAGTGCAGGTTTAGATTACCCTGGAGTAGGACCTGAACATAGCCATTTAAAAGAAATAGGTAGAGCAGAATATGG
ATCAGTCACAGATCAAGAAGCTTTAGACGCTTTAAAACTTGTTAGTGAACTAGAAGGAATTATTCCTGCACTTGAAACTT
CCCATGCCTTTGCTTGGTTAGATAAATTATGCCCTACTCTTGAAAAAGATACTCATATAGTTATCAATTGCTCTGGAAGA
GGCGACAAAGATGTTAATACTGTTGCATCTTCATTAGATATTTAA

Upstream 100 bases:

>100_bases
CTTGTGATTTTTTTTCTTGATTATCAAATTCGATCCAATTCTTTTTTCCCATTATTTTCAATATAATCTATAGTTAGTTA
ATACTTATTCTATAGAAAAA

Downstream 100 bases:

>100_bases
TCAATACCTTGGTATTGATGGGTCAATATATCTACTCCATCCATCAATACCCTCCTCCAAATTCCATATTTCGCTCACAA
TATTATTATCCAAGCACCAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MVSTFSRKDQNYKNDDLNQPSKEGRFGKYGGQYVPETLMPALFELETAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKTKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSFPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKEIGRAEYGSVTDQEALDALKLVSELEGIIPALETSHAFAWLDKLCPTLEKDTHIVINCSGR
GDKDVNTVASSLDI

Sequences:

>Translated_414_residues
MVSTFSRKDQNYKNDDLNQPSKEGRFGKYGGQYVPETLMPALFELETAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKTKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSFPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKEIGRAEYGSVTDQEALDALKLVSELEGIIPALETSHAFAWLDKLCPTLEKDTHIVINCSGR
GDKDVNTVASSLDI
>Mature_414_residues
MVSTFSRKDQNYKNDDLNQPSKEGRFGKYGGQYVPETLMPALFELETAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKTKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSFPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKEIGRAEYGSVTDQEALDALKLVSELEGIIPALETSHAFAWLDKLCPTLEKDTHIVINCSGR
GDKDVNTVASSLDI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.5104166666667, Blast_Score=435, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321412, Length=389, Percent_Identity=58.6118251928021, Blast_Score=470, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_PROM0 (A3PAN2)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090408.1
- ProteinModelPortal:   A3PAN2
- SMR:   A3PAN2
- STRING:   A3PAN2
- GeneID:   4912861
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_01841
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   PMAR167546:P9301ORF_0186-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 45079; Mature: 45079

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTFSRKDQNYKNDDLNQPSKEGRFGKYGGQYVPETLMPALFELETAASNAWKDKLFVE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELNHLLKTYVGRETPLYEAKRLTEHYKTKQATPRIWLKREDLNHTGAHKINNALGQALLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
IRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAEDIKRQSLNVFRMKLLGAEVKV
HHHCCHHEEEECCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
SFGSFPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGI
HHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHEEEECCCEEE
LHGSMSLLLQDDNGQVQEAHSISAGLDYPGVGPEHSHLKEIGRAEYGSVTDQEALDALKL
EECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
VSELEGIIPALETSHAFAWLDKLCPTLEKDTHIVINCSGRGDKDVNTVASSLDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MVSTFSRKDQNYKNDDLNQPSKEGRFGKYGGQYVPETLMPALFELETAASNAWKDKLFVE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELNHLLKTYVGRETPLYEAKRLTEHYKTKQATPRIWLKREDLNHTGAHKINNALGQALLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
IRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAEDIKRQSLNVFRMKLLGAEVKV
HHHCCHHEEEECCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
SFGSFPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGI
HHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHEEEECCCEEE
LHGSMSLLLQDDNGQVQEAHSISAGLDYPGVGPEHSHLKEIGRAEYGSVTDQEALDALKL
EECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
VSELEGIIPALETSHAFAWLDKLCPTLEKDTHIVINCSGRGDKDVNTVASSLDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA